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ADAM10 (ADAM10) ELISA试剂盒产品概述

Full name:
ADAM Metallopeptidase Domain 10 ELISA试剂盒 (ADAM10)
在www.antibodies-online.cn可供43 ADAM Metallopeptidase Domain 10 (ADAM10) ELISA试剂盒的12不同的供货商。 再加上,我们可以发ADAM10 抗体 (142)ADAM10 蛋白 (20)和数多这个蛋白质的别的产品。 总共209 ADAM10产品已列进来了。
别名:
1700031C13Rik, ad10, ADAM-10, ADAM 10, Adam10, cd156c, HsT18717, kuz, kuzbanian, LOC100219653, madm, wu:fc03d12, xadam10
list all ELISA KIts 基因 基因ID UniProt
ADAM10 11487 O35598
ADAM10 102 O14672
ADAM10 29650  

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引用最多的ADAM10 ELISA试剂盒

  1. Human ADAM10 ELISA Kit for Sandwich ELISA - ABIN414771 : Van Crombruggen, Holtappels, De Ruyck, Derycke, Tomassen, Bachert: RAGE processing in chronic airway conditions: involvement of Staphylococcus aureus and ECP. in The Journal of allergy and clinical immunology 2012 (PubMed)
    Show all 3 references for ABIN414771

适于 ADAM10 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. this study shows that during positive selection in the spleen, B-cell receptor signaling causes immature type 1 transitional B cells to become receptive to Notch (显示 NOTCH1 ELISA试剂盒) ligands via Taok3 (显示 TAOK3 ELISA试剂盒)-mediated surface expression of ADAM10

  2. Thus, Leda-1/Pianp is constitutively processed by proprotein convertases, sheddases including MMPs and ADAM10/17 and intramembrane protease gamma-secretase.

  3. ADAM10 was dispensable for alpha-toxin (显示 PLC ELISA试剂盒)-dependent xenophagic targeting of S. aureus, whereas a role for alpha-toxin (显示 PLC ELISA试剂盒) attack on the plasma membrane was confirmed.

  4. ADAM10 was essentially involved in maxillofacial bone development. ADAM10 conditional knock-out KO mice present craniofacial dysmorphia and bone defects. Impaired osteoblast differentiation,proliferation and apoptosis underlie the bone deformity.

  5. Newborn mice deficient in ADAM10 exhibited organ-specific vascular defects.

  6. Findings demonstrate the direct requirement of ADAM10 in cortical radial migration and reveal the underlying mechanism by linking ADAM10-initiated regulated intramembrane proteolysis of Notch (显示 NOTCH1 ELISA试剂盒) to the regulation of microtubule cytoskeleton through transcriptional control of Dcx (显示 DCX ELISA试剂盒) expression

  7. our data afford the new insight that miR (显示 MLXIP ELISA试剂盒)-103a inhibited abdominal aortic aneurysm (AAA (显示 AAAS ELISA试剂盒)) growth via targeting ADAM10, which might be a promising therapeutic strategy to alleviate AAA (显示 AAAS ELISA试剂盒).

  8. ADAM10 gene was predominantly expressed in the neurons of the cerebral cortex, hippocampus, thalamus and cerebellar granular cells in adult mouse CNS.

  9. Matrix metalloproteases ADAM10 and TACE (ADAM17) cleave AXL receptor tyrosine (显示 AXL ELISA试剂盒)kinase (Axl) in lupus-prone leukocytes.

  10. Loss of ADAM10 in murine liver results in hepatocyte necrosis and concomitant liver fibrosis. ADAM10 directly regulates expression of bile acid transporters but is dispensable for Notch2 (显示 NOTCH2 ELISA试剂盒)-dependent formation of the biliary system. Differentiation of liver progenitor cells to hepatocytes is augmented in the absence of ADAM10.

Human ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. 1,25D3 causes ectodomain shedding of TLR4 (显示 TLR4 ELISA试剂盒) and thereby decreases the responsiveness of cells to LPS (显示 IRF6 ELISA试剂盒). ADAM10, activated by extracellular Ca2 (显示 CA2 ELISA试剂盒)+ influx, was implicated in the ectodomain cleavage of TLR4 (显示 TLR4 ELISA试剂盒).

  2. The overexpression of MTERF4 induced a significant increase in the levels of APP protein and secreted Abeta 42 in HEK293-APPswe cells compared with control cells these results suggest that MTERF4 promotes the amyloidogenic processing of APP by inhibiting ADAM10 in HEK293-APPswe cells; therefore, MTERF4 may play an important role in the pathogenesis of Alzheimer's disease.

  3. Pre-incubation with simvastatin prior to treatment with IL-1beta (显示 IL1B ELISA试剂盒) + Oncostatin M (显示 OSM ELISA试剂盒) decreased the level of CD44 (显示 CD44 ELISA试剂盒) fragmentation, decreased the proportion of CD44 (显示 CD44 ELISA试剂盒) that transits into the lipid raft fractions, decreased ADAM10 activity and diminished the interaction between CD44 (显示 CD44 ELISA试剂盒) and ADAM10.

  4. ADAM17 (显示 ADAM17 ELISA试剂盒) and ADAM10 cleave Nectin-4 (显示 PVRL4 ELISA试剂盒) and release soluble Nectin-4 (显示 PVRL4 ELISA试剂盒) (sN4).

  5. Data show that mononuclear leukocytes (PBMC) AXL receptor tyrosine kinase (Axl (显示 AXL ELISA试剂盒)) is rescued by combined matrix metalloproteases ADAM10 and TACE (ADAM17 (显示 ADAM17 ELISA试剂盒)) inhibition.

  6. we found that ADAM10 expression was associated with a more rapid metastatic progression confirming its role in uveal melanoma metastasis.

  7. the TLR4 (显示 TLR4 ELISA试剂盒)/Gal-1 (显示 LGALS1 ELISA试剂盒) signaling pathway regulates lactate-mediated EMT (显示 ITK ELISA试剂盒) processes through the activation of ADAM10 and ADAM17 (显示 ADAM17 ELISA试剂盒) in colon cancer cells.

  8. Studies demonstrate a role for ADAM10 in the ectodomain shedding of LRP1 (显示 LRP1 ELISA试剂盒) in the brain and the clearance of Abeta (显示 APP ELISA试剂盒) across the blood-brain barrier, which may provide a novel strategy for attenuating Abeta (显示 APP ELISA试剂盒) accumulation in the AD brain

  9. In response to trastuzumab, both HER3 (显示 ERBB3 ELISA试剂盒) and the metalloprotease (显示 ADAM8 ELISA试剂盒) ADAM10 are simultaneously upregulated. The proteolytic activity of the latter then releases the HER3 (显示 ERBB3 ELISA试剂盒) ligand heregulin (显示 NRG1 ELISA试剂盒) from the cell surface to activate HER3 (显示 ERBB3 ELISA试剂盒) and confer resistance to trastuzumab by inducing compensatory growth factor receptor (显示 RYK ELISA试剂盒) signaling.

  10. Active ADAM10 promotes the carcinogenesis, invasion, metastasis and proliferation of ESCC and controls invasion and metastasis at least in part through the shedding of E-cadherin (显示 CDH1 ELISA试剂盒) activity.

Xenopus laevis ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. A dramatic decline in ephrinB2 (显示 EFNB2 ELISA试剂盒) protein levels on the absence of flotillin-1 (显示 FLOT1 ELISA试剂盒) expression is specific, and is partly the result of an increased susceptibility to cleavage by the metalloprotease (显示 ADAM8 ELISA试剂盒) ADAM10.

Pig (Porcine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. significantly increased expression of ADAM10 in the ISR versus non-ISR segment in diabetic minipigs

Cow (Bovine) ADAM Metallopeptidase Domain 10 (ADAM10) interaction partners

  1. Data show that ADAM10 and APLP2 (显示 APLP2 ELISA试剂盒) are expressed in proximal tubule cells, and that ADAM10 activity has a pronounced effect on expression of specific brush-border proteins.

  2. Intracellular trafficking of ADAM10 critically requires a novel sorting signal within its cytoplasmic domain.

  3. N-glycosylation is crucial for ADAM10 processing and resistance to proteolysis, and results suggest that it is required for full-enzyme activity.

ADAM10 抗原简介

Antigen Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin.

Alternative names and synonyms associated with ADAM10

  • a disintegrin and metalloprotease domain 10a (adam10a) Elisa Kit
  • ADAM metallopeptidase domain 10 (ADAM10) Elisa Kit
  • ADAM metallopeptidase domain 10 (LOC100219653) Elisa Kit
  • ADAM metallopeptidase domain 10 (Adam10) Elisa Kit
  • a disintegrin and metallopeptidase domain 10 (Adam10) Elisa Kit
  • ADAM metallopeptidase domain 10 (adam10) Elisa Kit
  • ADAM10 (LOC100101614) Elisa Kit
  • 1700031C13Rik Elisa Kit
  • ad10 Elisa Kit
  • ADAM-10 Elisa Kit
  • ADAM 10 Elisa Kit
  • Adam10 Elisa Kit
  • cd156c Elisa Kit
  • HsT18717 Elisa Kit
  • kuz Elisa Kit
  • kuzbanian Elisa Kit
  • LOC100219653 Elisa Kit
  • madm Elisa Kit
  • wu:fc03d12 Elisa Kit
  • xadam10 Elisa Kit

Protein level used designations for ADAM10

a disintegrin and metalloprotease domain 10a , ADAM metallopeptidase domain 10 , disintegrin and metalloproteinase domain-containing protein 10 , ADAM10 metallopeptidase , disintegrin and metalloproteinase domain-containing protein 10-like , ADAM 10 , a disintegrin and metalloprotease domain (ADAM) 10 , a disintegrin and metalloprotease domain 10 , kuzbanian protein homolog , mammalian disintegrin-metalloprotease , CDw156 , a disintegrin and metalloproteinase domain 10 , metalloprotease/disintegrin , xKuz , a disintegrin and metallopeptidase domain 10 , disintegrin-metalloproteinase , myelin-associated metalloproteinase

GENE ID SPECIES
566044 Danio rerio
701355 Macaca mulatta
746942 Pan troglodytes
100068314 Equus caballus
100169741 Pongo abelii
100219653 Taeniopygia guttata
100313545 Saccoglossus kowalevskii
100476350 Ailuropoda melanoleuca
100606667 Nomascus leucogenys
11487 Mus musculus
102 Homo sapiens
399187 Xenopus laevis
29650 Rattus norvegicus
374113 Gallus gallus
478321 Canis lupus familiaris
397345 Sus scrofa
282132 Bos taurus
100718999 Cavia porcellus
100101614 Oryctolagus cuniculus
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