anti-Insulin (INS) 抗体产品概述

Full name:
anti-Insulin 抗体 (INS)
在www.antibodies-online.cn可供1072 Insulin (INS) 抗体的36不同的供货商。 再加上,我们可以发Insulin 试剂盒 (219)Insulin 蛋白 (47)和数多这个蛋白质的别的产品。 总共1347 Insulin产品已列进来了。
别名:
AA986540, IDDM2, ILPR, Ins-2, ins1, ins1-a, InsII, Insulin, IRDN, Mody, Mody4, MODY10, proinsulin, xins, zgc:109842

所有可销售的anti-Insulin 抗体

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引用最多的anti-Insulin 抗体

  1. Cow (Bovine) Monoclonal Insulin Primary Antibody for EIA, IHC (p) - ABIN272321 : Roth, Klöppel, Madsen, Storch, Heitz: Distribution patterns of proinsulin and insulin in human insulinomas: an immunohistochemical analysis in 76 tumors. in Virchows Archiv. B, Cell pathology including molecular pathology 1993 (PubMed)
    Show all 3 references for 272321

  2. Cow (Bovine) Monoclonal Insulin Primary Antibody for IHC (p) - ABIN112181 : Madsen: Proinsulin-specific monoclonal antibodies. Immunocytochemical application as beta-cell markers and as probes for conversion. in Diabetes 1987 (PubMed)
    Show all 2 references for 112181

  3. Human Polyclonal Insulin Primary Antibody for EIA, FACS - ABIN372838 : Madsen, Knauf, Gotfredsen, Pilling, Sjögren, Andersen, Andersen, de Boer, Manova, Barlas, Vundavalli, Nyborg, Knudsen, Moelck, Fagin: GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation. in Endocrinology 2012 (PubMed)
    Show all 2 references for 372838

  4. Cow (Bovine) Monoclonal Insulin Primary Antibody for EIA, Func - ABIN111965 : Horejsí, Hilgert, Kristofová, Satayalai: Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor. in Immunology letters 1985 (PubMed)

  5. Human Monoclonal Insulin Primary Antibody for IHC (p) - ABIN616068 : Hilgert, Stolba, Kristofová, Stefanová, Bendlová, Lebl, Horejsí: A monoclonal antibody applicable for determination of C-peptide of human proinsulin by RIA. in Hybridoma 1991 (PubMed)

  6. Human Monoclonal Insulin Primary Antibody for IHC (p), IP - ABIN1107760 : Harper, Ullrich, Saunders: Localization of the human insulin gene to the distal end of the short arm of chromosome 11. in Proceedings of the National Academy of Sciences of the United States of America 1981 (PubMed)

  7. Cow (Bovine) Monoclonal Insulin Primary Antibody for EIA, IHC (fro) - ABIN112214 : Qin, Jiao, Chen, Zhou, Liang, Zhong: Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival. in Life sciences 2009 (PubMed)

更多抗Insulin的相互作用对抗体

Human Insulin (INS) interaction partners

  1. In pancreas sections from autoantibody-positive (Ab+) donors, insulin area and beta-cell mass are maintained before type 1 diabetes onset and that production of proinsulin increases. The pancreatic proinsulin-to-insulin area ratio was also increased in these donors with prediabetes

  2. microRNA-7 can differentiate human induced pluripotent stem cells into functional isletlike cell clusters secreting insulin in a short time.

  3. describe an alternative open reading frame within human insulin mRNA encoding a highly immunogenic polypeptide that is targeted by T cells in Type 1 Diabetes (T1D) patients. Cytotoxic T cells directed against the N-terminal peptide of this nonconventional product are present in the circulation of T1D patients, and such CD8 (显示 CD8A 抗体)(+) T cells are capable of killing human beta cells, and thereby may be diabetogenic.

  4. Insulin stimulation of Akt1 (显示 AKT1 抗体) and Akt2 (显示 AKT2 抗体) signaling in Cystic fibrosis (显示 S100A8 抗体) airway cells was diminished compared with that observed in airway cells expressing wild-type CFTR (显示 CFTR 抗体).

  5. The activation mechanism of insulin, IF-I, and IGF-II upon binding to corresponding receptors using molecular dynamics simulations has been reported.

  6. These data implicate the insulin-FoxM1 (显示 FOXM1 抗体)/PLK1 (显示 PLK1 抗体)/CENP-A (显示 CENPA 抗体) pathway-regulated mitotic cell-cycle progression as an essential component in the beta cell adaptation to delay and/or prevent progression to diabetes.

  7. The reproducibility of proinsulin:C-peptide ratio (PI:C) benefits from the automated simultaneous determination of both hormones. HOMA2-IR-corrected PI:C may serve as a minimally invasive alternative to the more tedious hyperglycemic clamp test

  8. Evening postprandial insulin and GIP (显示 GIP 抗体) responses and insulin resistance declined by over 30% after three meals that limited daily carbohydrate intake to 30% compared to no such changes after three 60%-carbohydrate meals, an effect that was independent of pre-meal exercise.

  9. The study results were suggestive of a positive association between Gly972Arg of IRS1 (显示 IRS1 抗体) and PCOS in the south Indian population, while INS, IRS2 (显示 IRS2 抗体), PPAR-G (显示 ARF6 抗体) and CAPN10 (显示 CAPN10 抗体) failed to show any association with PCOS in our studied population.

  10. We found inverse independent correlations between metabolic clearance rate of insulin (MCRI) and hepatic lipase (显示 LIPC 抗体) (P = 0.0004), insulin secretion (P = 0.0002), alanine aminotransferase (显示 ALT 抗体) (P = 0.0045), total fat mass (P = 0.014), and diabetes (P = 0.03). MCRI and apolipoprotein A-I (显示 APOA1 抗体) exhibited a positive independent correlation (P = 0.035).

Pig (Porcine) Insulin (INS) interaction partners

  1. Study used well-tempered bias exchange metadynamics simulations to determine the equilibrium ensembles of an insulin molecule under amyloidogenic conditions of low pH and high temperature. The folded state of a single insulin molecule was shown to be the most stable, longest-lived state even under amyloidogenic conditions.

  2. The findings are consistent with previous studies that indicate a link between Na,K-ATPase (显示 ATP1A1 抗体) activity and SFK signaling.

  3. PTPLAD1 (显示 PTPLAD1 抗体) and AMPK (显示 PRKAA1 抗体) are rapidly compartmentalized within the plasma membrane (PM) and Golgi/endosome fractions after insulin stimulation and that ATIC (显示 ATIC 抗体) later accumulates in the Golgi/endosome fraction.

  4. Pdx-1 (显示 PDX1 抗体), MafA (显示 MAFA 抗体) and NeuroD1 (显示 NEUROD1 抗体) bind to the A, C and E elements in the insulin promoter and regulate the transcriptional activity of the insulin promoter.

  5. The interplay of the adiponectin (显示 ADIPOQ 抗体) system, TNFalpha (显示 TNF 抗体) and insulin at a transcriptional level and, their effects on the adipogenic transcription factor PPARgamma (显示 PPARG 抗体), as well as on the activation of main insulin signaling pathways, is reported.

  6. Thermodynamics of insulin unfolding have been quantified by differential scanning calorimetry and thermal unfolding measurements to determine the extent and nature of their stabilization of the insulin hexamer.

  7. Exposing the hydrophobic core of insulin can induce the increase of amyloidogenicity and formation of higher-order polymerized fibrils, which is less toxic to membranes.

  8. Data suggest that a mutation in INS (C94Y) results a transgenic disease model for the investigation of permanent neonatal diabetes.

  9. The results show that modulation of plasma insulin levels by dietary carbohydrates seems possible in anabolic sows, but IGF-I (显示 IGF1 抗体) levels are less easily modified.

  10. insulin increased GCLc (显示 GCLC 抗体) promoter activity, which required a prerequisite increase or decrease in medium glucose

Cow (Bovine) Insulin (INS) interaction partners

  1. Insulin signaling role in skeletal muscle atrophy and autophagy in in transition and postpartum period

  2. Differences between human and bovine insulin kinetics under shear

  3. increased sensitivity to glucose clearance and skeletal muscle insulin signaling during dietary restriction

  4. Hormonal gene expression involved in residual feed intake in dairy cows may be related to the molecular regulation of the leptin (显示 LEP 抗体)-NPY (显示 NPY 抗体) and insulin signaling pathways.

  5. Raman spectra of amino acids by Density Functional Theory method have been calculated. Experimental Raman spectra of insulin has been done. The simulated Raman spectrum of insulin is obtained from amino acid spectrum.

  6. Contains Binding kinetics for insulin binding

  7. Using synchrotron radiation (SR), the crystal structures of T6 bovine insulin complexed with Ni(2 (显示 VMP1 抗体)+) and Cu(2+) were solved to 1.50 and 1.45 A resolution, respectively.

  8. Thermodynamics of insulin unfolding have been quantified by differential scanning calorimetry and thermal unfolding measurements to determine the extent and nature of their stabilization of the insulin hexamer.

  9. The present study examined the effect of insulin-mediated activation of the mammalian target of rapamycin (显示 FRAP1 抗体) complex 1 (MTORC1) signaling network on the proliferation of primary culture of theca-interstitial (T-I) cells.

  10. In-situ spectroscopic investigation of ultrasonic assisted unfolding and aggregation of insulin.

Rabbit Insulin (INS) interaction partners

  1. insulin supports early initiation of the mesodermal factor Brachyury (显示 TBX1 抗体) and the signalling molecules Wnt3a (显示 WNT3A 抗体) and Wnt4 (显示 WNT4 抗体) as well as the progression of mesoderm formation

  2. Data show that type 1 diabetic blastocyst did not express insulin mRNA.

Mouse (Murine) Insulin (INS) interaction partners

  1. report that EndMTs occur in the diabetic endothelium of Ins2Akita/wt mouse, and show that induction of sex determining region Y-box 2 (Sox2 (显示 SOX2 抗体)) is a mediator of excess BMP signaling that results in activation of EndMTs and increased vascular calcification

  2. Transplantation of transduced hematopoietic stem cells (HSCs) expressing proinsulin II prevents diabetes development.

  3. Wnt3a increased the expression of NeuroD1 and Ins2 in the hypothalamus.

  4. Data suggest that resveratrol acts on differentiating preadipocytes by inhibiting insulin signaling, mitochondrial biogenesis, and lipogenesis.

  5. have characterized the distinctive sex-specific phenotypes exhibited by the ApoE(-/-):Ins2(+/Akita) mouse model and present evidence for the action of sex hormones on pancreatic beta-cell function

  6. Data indicate that Src homology-2 domain containing protein B (SHB) deficiency causes a chronic increase in beta-cell focal adhesion kinase (FAK) activity that perturbs the normal insulin secretory characteristics of beta-cells.

  7. Mouse Ins2 and Ins1 promoters were transiently activated in mouse fetal hepatocytes of embryonic days 13.5 and 16.5, respectively.

  8. Data indicate that insulin/incomplete Freund's adjuvant (IFA) does not prevent but induces diabetes in RIP-CD80GP transgenic mice.

  9. RORalpha is a transcriptional activator of insulin.

  10. Mice deficient in coinhibitory PD-L1 (显示 CD274 抗体) or PD-1 (显示 PDCD1 抗体) molecules (PD-L1 (显示 CD274 抗体)(-/-) and PD-1 (显示 PDCD1 抗体)(-/-) mice), were used to study induction of preproinsulin (ppins)-specific CD8 (显示 CD8A 抗体) T-cell responses and experimental autoimmune diabetes.

Zebrafish Insulin (INS) interaction partners

  1. Temporal and spatial expression of two insulin genes (insa and insab) during early developmental stages.

  2. These findings suggest that GHRL (显示 GHRL 抗体) regulates INS synthesis by mediating its action on growth hormone secretagogue-receptor (显示 GHSR 抗体) in the central nervous system and partly involved in carbohydrate-glycogen (显示 GYS2 抗体) metabolism.

  3. Our results indicate that in adult tilapia insulin expression is not restricted to the endocrine pancreatic cells, but also occurs in endocrine cells of the pituitary gland and in the neuronal cells of the brain.

Insulin (INS) 抗原简介

Antigen Summary

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with Insulin (INS)

  • insulin (ins) 抗体
  • insulin precursor (PIN) 抗体
  • insulin (INS) 抗体
  • insulin (Ins) 抗体
  • insulin II (Ins2) 抗体
  • insulin-like (LOC100060077) 抗体
  • preproinsulin (ins) 抗体
  • AA986540 抗体
  • IDDM2 抗体
  • ILPR 抗体
  • Ins-2 抗体
  • ins1 抗体
  • ins1-a 抗体
  • InsII 抗体
  • Insulin 抗体
  • IRDN 抗体
  • Mody 抗体
  • Mody4 抗体
  • MODY10 抗体
  • proinsulin 抗体
  • xins 抗体
  • zgc:109842 抗体

Protein level used designations for anti-Insulin (INS) 抗体

insulin I , insulin , preproinsulin , proinsulin , insulin-2 , insa

GENE ID SPECIES
100101718 Xenopus (Silurana) tropicalis
100533403 Aplysia californica
3630 Homo sapiens
397415 Sus scrofa
280829 Bos taurus
100009181 Oryctolagus cuniculus
101684928 Mustela putorius furo
483665 Canis lupus familiaris
493804 Felis catus
100379579 Cavia porcellus
396145 Gallus gallus
101794427 Anas platyrhynchos
449570 Pan troglodytes
16334 Mus musculus
100060077 Equus caballus
30262 Danio rerio
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