anti-GNB1 (GNB1) 抗体产品概述

在www.antibodies-online.cn可供61 Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1) 抗体的13不同的供货商。 再加上,我们可以发GNB1 试剂盒 (30)GNB1 蛋白 (4)和数多这个蛋白质的别的产品。 总共100 GNB1产品已列进来了。
别名:
AA409223, C77571, Gnb-1, XGB1, xgbeta1
列出全部抗体 基因 基因ID UniProt
GNB1 14688 P62874
GNB1 2782 P62873
GNB1 24400 P54311

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更多抗GNB1的相互作用对抗体

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1) interaction partners

  1. Data, including data from studies using transgenic/knockout mice, suggest that Ppp1ca (显示 PPP1CA 抗体) and Gnb1 interact in quiescent platelets; then, Ppp1ca (显示 PPP1CA 抗体) and Plcb3 (显示 PLCB3 抗体) interact during platelet aggregation; thus, Gnb1 enlists Ppp1ca (显示 PPP1CA 抗体) to modulate G protein-coupled receptor (显示 GPR34 抗体) signaling. (Ppp1ca (显示 PPP1CA 抗体) = protein phosphatase 1 (显示 PPP1CB 抗体), catalytic subunit alpha; Gnb1 = guanine nucleotide-binding protein (显示 TRIM23 抗体), subunit beta-1; Plcb3 (显示 PLCB3 抗体) = phospholipase C (显示 PLC 抗体), subunit beta-3)

  2. It was concluded that GIRK2 (显示 KCNJ6 抗体), through its dual responsiveness to G protein beta (显示 GNB3 抗体)-gamma and Na+, mediates a form of neuronal inhibition that is amplifiable in the setting of excess electrical activity.

  3. During corticogenesis, a cilium-transduced, noncanonical IGF-1R (显示 IGF1R 抗体)-Gbetagamma-phospho(T94)Tctex-1 (显示 DYNLT1 抗体) signaling pathway promotes the proliferation of neural progenitors through modulation of ciliary resorption and G1 length.

  4. ectopically expressed cTalpha (显示 PCYT1A 抗体) 1) forms a heterotrimeric complex with rod Gbeta (显示 SUCLG2 抗体)(1)gamma(1), and substitutes equally for rTalpha in generating photoresponses initiated by either rhodopsin (显示 RHO 抗体) or S-cone opsin (显示 RHO 抗体)

  5. Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (显示 GNAO1 抗体)) upon activation of mGluR6 (显示 GRM6 抗体) closes the TRPM1 (显示 TRPM1 抗体) channel, perhaps via a direct interaction.

  6. WDR26 (显示 WDR26 抗体) is a novel Gbetagamma-binding protein that is required for the efficacy of Gbetagamma signaling and leukocyte migration

  7. Our data suggest that the G-protein beta(1)gamma(2) dimer may play an important regulatory role in skeletal muscle excitation-contraction coupling.

  8. G protein subunits beta1 and beta2 have different roles in neutrophil function, as revealed by gene expression silencing in primary mouse neutrophils

  9. G betagamma binds HDAC5 (显示 HDAC5 抗体) and inhibits its transcriptional co-repression activity

  10. G protein betagamma subunits stimulate type V and VI adenylyl cyclases

Human Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1) interaction partners

  1. Germline De Novo Mutations in GNB1 Cause Severe Neurodevelopmental Disability, Hypotonia, and Seizures.

  2. we demonstrate a pathogenic role of de novo and autosomal dominant mutations in GNB1 as a cause of Global developmental delay and provide insights how perturbation in heterotrimeric G protein function contributes to the disease

  3. PhLP1 binding stabilizes the Gbeta (显示 SUCLG2 抗体) fold, disrupting interactions with CCT (显示 FLVCR2 抗体) and releasing a PhLP1-Gbeta (显示 SUCLG2 抗体) dimer for assembly with Ggamma.

  4. GNB1 and GNB2 alterations confer transformed and resistance phenotypes across a range of human tumors and may be targetable with inhibitors of G protein signaling.

  5. Data indicate that endogenous mTOR (显示 FRAP1 抗体) interacts with Gbetagamma.

  6. During corticogenesis, a cilium-transduced, noncanonical IGF-1R (显示 IGF1R 抗体)-Gbetagamma-phospho(T94)Tctex-1 (显示 DYNLT1 抗体) signaling pathway promotes the proliferation of neural progenitors through modulation of ciliary resorption and G1 length.

  7. GNB1 plays an important role in the mTOR (显示 FRAP1 抗体)-related anti-apoptosis pathway and can potentially be targeted in the treatment of human breast cancer.

  8. Findings suggest a wide-ranging mechanism by which direct interaction of Gbetagamma with specific chromatin bound transcription factors regulates functional gene networks in response to GPCR (显示 NMUR1 抗体) activation in cells including the angiotensin II type 1 receptor (显示 AGTR1 抗体).

  9. This study provided evidence that GNB1 gene polymorphisms are related to rapid virological response in HCV-1 and HCV-2 (显示 BMPER 抗体) infected patients. GNB1 may play an important role in activating the antiviral response prior to treatment.

  10. WDR26 (显示 WDR26 抗体) is a novel Gbetagamma-binding protein that is required for the efficacy of Gbetagamma signaling and leukocyte migration

Xenopus laevis Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1) interaction partners

  1. Gbeta1gamma2-mediated epithelial sodium channel (ENaC (显示 SCNN1A 抗体)) inhibition involves activation of phospholipase C-beta (显示 PLCb4 抗体) and its enzymatic products that induce protein kinase C (显示 PKC 抗体) and ERK1/2 (显示 MAPK1/3 抗体) signaling pathways.

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1) interaction partners

  1. Data suggest that a hetero-multimer complex forms between light-activated rhodopsin (显示 RHO 抗体) and light-activated heterotrimeric transducin (显示 GNAT1 抗体) (T-alpha-1, Gnb1, Gngt1 (显示 GNGT1 抗体)); the stoichiometry is 1:1 rhodopsin:transducin. The complex appears to form on native rod outer segment membranes upon light activation.

  2. The PIP2-induced orientation of the GRK2 (显示 ADRBK1 抗体)-Gbeta1gamma2 complex is therefore most likely caused by specific interactions between PIP2 and the GRK2 (显示 ADRBK1 抗体) PH domain.

  3. determined the crystallographic structure of GRK2 in complex with G protein beta1gamma2 subunits

  4. conclude that GNB1 constitutes over 99% of the GNbeta expressed in bovine rod outer segments and displays structural heterogeneity that is due to post-translational modification, some of which is due to phosphorylation of GNB1.

GNB1 抗原简介

Antigen Summary

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals.

Alternative names and synonyms associated with GNB1

  • guanine nucleotide binding protein (G protein), beta 1 (Gnb1) 抗体
  • guanine nucleotide binding protein (G protein), beta polypeptide 1 (GNB1) 抗体
  • guanine nucleotide binding protein (G protein), beta polypeptide 1 (Gnb1) 抗体
  • guanine nucleotide binding protein (G protein), beta polypeptide 1 (gnb1) 抗体
  • AA409223 抗体
  • C77571 抗体
  • Gnb-1 抗体
  • XGB1 抗体
  • xgbeta1 抗体

Protein level used designations for GNB1

guanine nucleotide binding protein, beta 1 , guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 , transducin beta chain 1 , G protein, beta-1 subunit , beta subunit, signal-transducing proteins GS/GI , guanine nucleotide-binding protein G(I)/G(S)/G(T) beta subunit 1 , Guanine nucleotide-binding protein beta 1 , guanine nucleotide binding protein (G protein), beta 1 , guanine nucleotide-binding protein, beta-1 subunit , rod transducin , beta 1 subunit of heterotrimeric GTP-binding protein

GENE ID SPECIES
14688 Mus musculus
2782 Homo sapiens
24400 Rattus norvegicus
403912 Canis lupus familiaris
399330 Xenopus laevis
281201 Bos taurus
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