anti-YAP1 (YAP1) 抗体产品概述

在www.antibodies-online.cn可供244 Yes-Associated Protein 1 (YAP1) 抗体的24不同的供货商。 再加上,我们可以发YAP1 试剂盒 (26)YAP1 蛋白 (10)和数多这个蛋白质的别的产品。 总共293 YAP1产品已列进来了。
别名:
AI325207, cb194, HCCA1, HCCA2, sb:cb194, si:ch211-181p1.5, si:dkey-3b8.3, wu:fc18c04, xyap, yap, YAP1, yap2, yap65, yki, Yorkie, YY1AP, zgc:158380
列出全部抗体 基因 基因ID UniProt
YAP1 10413 P46937
YAP1 22601 P46938
YAP1 363014 Q2EJA0

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更多抗YAP1的相互作用对抗体

Human Yes-Associated Protein 1 (YAP1) interaction partners

  1. Studies indicate that the transcriptional co-activators YAP and TAZ (显示 TAZ 抗体) recently emerged as key mediators of the biological effects that are observed in response to extracellular matrix (ECM (显示 MMRN1 抗体)) elasticity and cell shape.

  2. This identifies the YAP1/TEAD1 (显示 TEAD1 抗体) complex as the representative dysregulated profile of Hippo signaling in OS and provides proof-of-principle that targeting TEAD1 (显示 TEAD1 抗体) may be a therapeutic strategy of osteosarcoma.

  3. a stiffness-dependent YAP/TAZ (显示 TAZ 抗体)-mediated positive feedback loop that drives remodeling phenotypes in pulmonary artery smooth muscle cells via reduced COX-2 (显示 COX2 抗体) and prostaglandin activity.

  4. Study found that LPS (显示 IRF6 抗体)-induced activation and nuclear accumulation of YAP accelerated human pulmonary micro-vascular endothelial cell apoptosis.

  5. ETAR (显示 EDNRA 抗体) stimulation acted via downstream G-protein Galphaq (显示 GNAQ 抗体)/11 and Rho GTPase (显示 RACGAP1 抗体) to suppress the Hippo pathway, thus leading to YAP/TAZ (显示 TAZ 抗体) activation, which was required for ETAR (显示 EDNRA 抗体)-induced tumorigenesis. Overall, these results indicate a critical role of the YAP/TAZ (显示 TAZ 抗体) axis in ETAR (显示 EDNRA 抗体) signaling

  6. Various studies show that in human cancers, the Hippo pathway is frequently deregulated allowing YAP1 and TAZ (显示 TAZ 抗体) to escape the inhibition by the Hippo pathway. The upregulation of YAP1 and TAZ (显示 TAZ 抗体) induces epithelial-mesenchymal transition and increases drug resistance in cancer cells. [review]

  7. MiR (显示 MLXIP 抗体)-590-5p is downregulated in A375 cells, and inhibits the invasion and migration of A375 cells by directly regulating the expression of YAP1.

  8. High YAP1 expression is associated with gastric cancer.

  9. establish a new cancer stem cell signalling pathway downstream of mtp53 in which AKT2 (显示 AKT2 抗体) regulates WIP (显示 WIPF1 抗体) and controls YAP/TAZ (显示 TAZ 抗体) stability.

  10. Results show that MiR (显示 MLXIP 抗体)-424-3p directly and negatively regulates YAP1 in non-small cell lung cancer cells through binding its 3'-untranslated region.

Mouse (Murine) Yes-Associated Protein 1 (YAP1) interaction partners

  1. These results suggest that YAP promotes muscle differentiation by activating the Abl (显示 ABL1 抗体)/Src (显示 SRC 抗体)/MEKK3 (显示 MAP3K3 抗体)/MEK5 (显示 MAP2K5 抗体)/ERK5 (显示 MAPK7 抗体) kinase cascade.

  2. data demonstrate that Yap1 is a required factor for proper differentiation of mouse embryonic stem cells, while remaining dispensable for self-renewal

  3. these results identify a novel function of YAP in neocortical astrocytic differentiation and proliferation, and reveal a BMP2 (显示 BMP2 抗体)-YAP-SMAD1 (显示 SMAD1 抗体) pathway underlying astrocytic differentiation in the developing mouse neocortex.

  4. Wnt/beta-catenin signaling via Axin2 is required for myogenesis and, together with YAP/Taz and Tead1, active in IIa/IIx muscle fibers

  5. Epicardial YAP/TAZ (显示 TAZ 抗体) orchestrate an immunosuppressive response following myocardial infarction

  6. YAP negatively regulated an antiviral immune response. YAP deficiency resulted in enhanced innate immunity, a diminished viral load, and morbidity in vivo. YAP blocked dimerization of the transcription factor IRF3 (显示 IRF3 抗体) and impeded translocation of IRF3 (显示 IRF3 抗体) to the nucleus after viral infection.

  7. the transcription regulators YAP and TAZ (显示 TAZ 抗体) localise to the nucleus in the basal layer of skin and are elevated upon wound healing.

  8. Yap and Taz (显示 TAZ 抗体) are activated in Schwann cells by mechanical stimuli and regulate Schwann cell proliferation and transcription of basal lamina receptor genes

  9. This paper explored the role of Yes-associated protein (Yap) in neuromuscular junction (NMJ) formation and regeneration. Yap is a major effector of the Hippo pathway that regulates cell proliferation and differentiation during development and restricts tissue growth in adult animals. However, its role in synapse formation remains poorly understood.

  10. Yap determines the regional fate of the RPE (显示 RPE 抗体) during early eye development. Yap is essential for maintaining apical polarity and cell to cell adhesion. Yap regulates the proliferation and survival of retinal progenitor cells. Yap has an evolutionarily conserved, instructive role in regional specification, maintenance of junctional integrity and precise regulation of cell proliferation during neuroepithelial development.

Zebrafish Yes-Associated Protein 1 (YAP1) interaction partners

  1. During vascular regression, Yap/Taz is activated by blood circulation in the endothelial cells. This leads to induction of Ctgf and actin polymerization. Interference with Yap/Taz activation decreased Ctgf production, which decreased actin polymerization and vascular regression.

  2. that Yap1 entered the nucleus and promoted transcription in response to blood flow.

  3. that Yap1 integrates the anabolic demands of tissue growth during development and tumorigenesis by reprogramming nitrogen metabolism to stimulate nucleotide biosynthesis

  4. Amotl2a (显示 AMOTL2 抗体) function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 and the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) effector Lef1 (显示 LEF1 抗体).

  5. data reveals that Yap is required for pronephric duct integrity, maintenance of baso-lateral cell polarity, and ciliogenesis during zebrafish kidney development

  6. Yap/Taz (显示 TAZ 抗体)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.

  7. Yap is essential for fin regeneration and that its function is dependent on mechanical tension, conferred by a balancing act of cell density and cytoskeleton activity.

  8. When transcriptional coactivators Yap and Taz (显示 TAZ 抗体) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.

  9. Yap coordinately regulates cell proliferation and apoptosis and is required for dorsoventral axis formation, gastrulation, cardiogenesis, hematopoiesis, and somitogenesis.

  10. zebrafish yap is required for the development of the brain, eyes, and neural crest during embryogenesis.

Xenopus laevis Yes-Associated Protein 1 (YAP1) interaction partners

  1. Yap1 has a crucial role in controlling the limb regenerative capacity in Xenopus

YAP1 抗原简介

Antigen Summary

The encoded gene product presumably interacts with YY1 protein\; however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with YAP1

  • Yes-associated protein 1 (YAP1) 抗体
  • Yes-associated protein 1, 65kDa (YAP1) 抗体
  • Yes-associated protein 1, 65kDa (LOC787360) 抗体
  • Yes-associated protein 1, 65kDa (LOC100219556) 抗体
  • yes-associated protein 1 (Yap1) 抗体
  • Yes-associated protein 1 (yap1) 抗体
  • Yes-associated protein 1 (Yap1) 抗体
  • YY1 associated protein 1 (YY1AP1) 抗体
  • AI325207 抗体
  • cb194 抗体
  • HCCA1 抗体
  • HCCA2 抗体
  • sb:cb194 抗体
  • si:ch211-181p1.5 抗体
  • si:dkey-3b8.3 抗体
  • wu:fc18c04 抗体
  • xyap 抗体
  • yap 抗体
  • YAP1 抗体
  • yap2 抗体
  • yap65 抗体
  • yki 抗体
  • Yorkie 抗体
  • YY1AP 抗体
  • zgc:158380 抗体

Protein level used designations for YAP1

Yes-associated protein 1, 65kDa , Yes-associated protein 1, 65 kD , 65 kDa Yes-associated protein , yes-associated protein 2 , yorkie homolog , yes-associated protein, 65 kDa , yap , YY1-associated protein 1 , hepatocellular carcinoma susceptibility protein , hepatocellular carcinoma-associated protein 2

GENE ID SPECIES
100068834 Equus caballus
451506 Pan troglodytes
617423 Bos taurus
787360 Bos taurus
100219556 Taeniopygia guttata
10413 Homo sapiens
22601 Mus musculus
363014 Rattus norvegicus
561411 Danio rerio
100381098 Xenopus laevis
396171 Gallus gallus
479465 Canis lupus familiaris
100336629 Bos taurus
100726570 Cavia porcellus
100913160 Ovis aries
55249 Homo sapiens
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