Use your antibodies-online credentials, if available.
抗Human YAP1 抗体:
抗Mouse (Murine) YAP1 抗体:
抗Rat (Rattus) YAP1 抗体:
Human Monoclonal YAP1 Primary Antibody for IF, IHC (p) - ABIN564526
Lau, Murray, Houshmandi, Xu, Gutmann, Yu: Merlin is a potent inhibitor of glioma growth. in Cancer research 2008
Show all 17 Pubmed References
Human Polyclonal YAP1 Primary Antibody for ChIP, ICC - ABIN258559
Kapoor, Yao, Ying, Hua, Liewen, Wang, Zhong, Wu, Sadanandam, Hu, Chang, Chu, Al-Khalil, Jiang, Xia, Fletcher-Sananikone, Lim, Horwitz, Viale, Pettazzoni, Sanchez, Wang, Protopopov, Zhang, Heffernan et al.: Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer. ... in Cell 2014
Show all 12 Pubmed References
Human Monoclonal YAP1 Primary Antibody for FACS, IHC - ABIN969574
Fernandez-L, Northcott, Dalton, Fraga, Ellison, Angers, Taylor, Kenney: YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation. in Genes & development 2009
Show all 2 Pubmed References
Human Polyclonal YAP1 Primary Antibody for IF (p), IHC (p) - ABIN701485
Li, Shang, Shu, Zhang, Ji, Sun, Li, Xie: gga-miR-375 plays a key role in tumorigenesis post subgroup J avian leukosis virus infection. in PLoS ONE 2014
Dog (Canine) Polyclonal YAP1 Primary Antibody for ELISA, WB - ABIN4219868
Zender, Spector, Xue, Flemming, Cordon-Cardo, Silke, Fan, Luk, Wigler, Hannon, Mu, Lucito, Powers, Lowe: Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. in Cell 2006
Human Polyclonal YAP1 Primary Antibody for ICC, IF - ABIN4366489
Li, Lim, Chen, McCabe, Kim, Zhang, Mao: Spinal expression of Hippo signaling components YAP and TAZ following peripheral nerve injury in rats. in Brain research 2013
YAP negatively regulates differentiation of Vascular smooth muscle cells (VSMCs) derived from cardiovascular progenitor cell (CVPC) by decreasing transcription of myocardin (显示 MYOCD 抗体) in a NKX2.5 (显示 NKX2-5 抗体)-dependent manner.
Studied the effect of TEAD4 (显示 TEAD4 抗体) acylation on its interaction with YAP and TAZ (显示 TAZ 抗体); found YAP and TAZ (显示 TAZ 抗体) bind in a similar manner to both acylated and non-acylated TEAD4 (显示 TEAD4 抗体). Also found TEAD4 (显示 TEAD4 抗体) acylation significantly enhances its stability.
Studies indicate that the transcriptional co-activators YAP and TAZ (显示 TAZ 抗体) recently emerged as key mediators of the biological effects that are observed in response to extracellular matrix (ECM (显示 MMRN1 抗体)) elasticity and cell shape.
results demonstrated that miR (显示 MLXIP 抗体)-195-5p was a potent suppressor of YAP1, and miR (显示 MLXIP 抗体)-195-5p-mediated downregulation of YAP1 significantly reduced tumor development in a mouse colorectal cancer xenograft model.
Data indicate an activation of Yes-associated protein 1 (YAP1) signaling after platelet incubation.
YAP expression and progesterone receptor (显示 PGR 抗体) status were independent favorable predictors of disease-free survival and overall survival, respectively, among patients with breast cancer.
Our findings suggest that LATS1 (显示 LATS1 抗体) is a potential candidate tumor suppressor and inhibits the growth and metastasis of gastric carcinoma cells via downregulation of the YAP signaling.
14-3-3zeta (显示 YWHAZ 抗体) recruited YAP and p-LATS (显示 LATS1 抗体) to form a complex under high cells density status and 14-3-3zeta (显示 YWHAZ 抗体) other than YAP or phospho-LATS (显示 LATS1 抗体) was the key regulatory molecule of this complex.
Together, these data illustrate that YAP/TAZ (显示 TAZ 抗体) signaling is responsive to hydrogel stiffness and degradability, but the outcome is dependent on the dimensionality of cell-biomaterial interactions.
adult human and mouse hearts had more Taz (显示 TAZ 抗体) than Yap1 by mRNA and protein expression and their increases in diseased hearts were proportional and did not change Yap1/Taz (显示 TAZ 抗体) ratio. Yap1, Taz (显示 TAZ 抗体), and Tead1 (显示 TEAD1 抗体) were accumulated in the nuclear fraction and cardiomyocyte nuclei of diseased hearts
Yap1 has a crucial role in controlling the limb regenerative capacity in Xenopus
YAP1 enhanced cementoblast mineralization in vitro. YAP1 exerted its effect on the cementoblast partly by regulating the Smad (显示 SMAD1 抗体)-dependent BMP and Erk1/2 (显示 MAPK1/3 抗体) signaling pathways.
A crucial role for YAP and TAZ (显示 TAZ 抗体) in the maintenance of the postnatal adrenal cortex.
v-Src (显示 SRC 抗体) prevents nuclear exclusion of YAP through a decrease in the phosphorylation of YAP at Ser127 in multinucleated cells.
Dystrophin-glycoprotein complex component dystroglycan 1 (Dag1) directly binds to the Hippo pathway effector Yap to inhibit cardiomyocyte proliferation in mice
P38 MAPK (显示 MAPK14 抗体)-mediated YAP activation controls mechanical-tension-induced pulmonary alveolar regeneration.
YAP1 exerted its effect on the chondrocyte differentiation by activating the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling pathway
Nuclear YAP does not play a significant physiological role during oocyte development in mammals.
identify the mesenchymal requirement of YAP/TAZ (显示 TAZ 抗体) in the gastrointestinal tract and highlight the functional interplays between Hippo and Hedgehog (显示 SHH 抗体) signaling underlying temporal and spatial control of tissue growth and specification in developing gut (显示 GUSB 抗体)
findings indicate that HIF-2alpha (显示 EPAS1 抗体) increases cancer cell growth by up-regulating YAP1 activity
found that epidermal YAP activity drives GLI2 (显示 GLI2 抗体) nuclear accumulation in the skin of YAP2-5SA-DeltaC mice, which depends on epidermal beta-catenin (显示 CTNNB1 抗体) activation
YAP activation is a hallmark of malignant brain tumours.
During vascular regression, Yap/Taz is activated by blood circulation in the endothelial cells. This leads to induction of Ctgf and actin polymerization. Interference with Yap/Taz activation decreased Ctgf production, which decreased actin polymerization and vascular regression.
that Yap1 entered the nucleus and promoted transcription in response to blood flow.
that Yap1 integrates the anabolic demands of tissue growth during development and tumorigenesis by reprogramming nitrogen metabolism to stimulate nucleotide biosynthesis
Amotl2a (显示 AMOTL2 抗体) function in the control of lateral line primordium cell proliferation is mediated together by the Hippo pathway effector Yap1 and the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) effector Lef1 (显示 LEF1 抗体).
data reveals that Yap is required for pronephric duct integrity, maintenance of baso-lateral cell polarity, and ciliogenesis during zebrafish kidney development
Yap/Taz (显示 TAZ 抗体)-Tead activity is necessary and sufficient for optic vesicle progenitors to adopt retinal pigment epithelium identity in zebrafish.
Yap is essential for fin regeneration and that its function is dependent on mechanical tension, conferred by a balancing act of cell density and cytoskeleton activity.
When transcriptional coactivators Yap and Taz (显示 TAZ 抗体) were restricted from interacting with Tead transcription factors through expression of a dominant negative transgene, cardiac precursors failed to migrate completely to the midline.
Yap coordinately regulates cell proliferation and apoptosis and is required for dorsoventral axis formation, gastrulation, cardiogenesis, hematopoiesis, and somitogenesis.
The data suggest that TEAD relocation and/or YAP degradation following its phosphorylation down-regulates IFNT gene transcription after conceptus attachment to the uterine endometrium.
This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
65 kDa Yes-associated protein
, yes-associated protein 2
, yorkie homolog
, Yes-associated protein 1, 65kDa
, Yes-associated protein 1, 65 kD
, yes-associated protein, 65 kDa