anti-MAP2K6 (MAP2K6) 抗体产品概述

Full name:
anti-Mitogen-Activated Protein Kinase Kinase 6 抗体 (MAP2K6)
在www.antibodies-online.cn可供215 Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) 抗体的26不同的供货商。 再加上,我们可以发MAP2K6 试剂盒 (22)MAP2K6 蛋白 (18)和数多这个蛋白质的别的产品。 总共270 MAP2K6产品已列进来了。
列出全部抗体 基因 基因ID UniProt
MAP2K6 5608 P52564
MAP2K6 114495  
MAP2K6 26399 P70236



最受欢迎的抗anti-MAP2K6 (MAP2K6) 抗体


抗Human MAP2K6 抗体:

抗Rat (Rattus) MAP2K6 抗体:

抗Mouse (Murine) MAP2K6 抗体:

所有可销售的anti-MAP2K6 抗体


引用最多的anti-MAP2K6 抗体

  1. Human Monoclonal MAP2K6 Primary Antibody for IF, WB - ABIN393607 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 393607

  2. Human Polyclonal MAP2K6 Primary Antibody for IF, IHC (p) - ABIN197354 : Wang, Chen, Liao, Deng, Zhou, Huang, Sun: Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence. in Molecular and cellular biology 2002 (PubMed)
    Show all 2 references for 197354

  3. Human Polyclonal MAP2K6 Primary Antibody for IF, IHC (p) - ABIN196864 : Raingeaud, Whitmarsh, Barrett, Dérijard, Davis: MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. in Molecular and cellular biology 1996 (PubMed)
    Show all 2 references for 196864

  4. Human Monoclonal MAP2K6 Primary Antibody for ICC, FACS - ABIN969269 : Arning, Monté, Hansen, Wieczorek, Jagiello, Akkad, Andrich, Kraus, Saft, Epplen: ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease. in Journal of molecular medicine (Berlin, Germany) 2008 (PubMed)

  5. Human Polyclonal MAP2K6 Primary Antibody for IF (p), IHC (p) - ABIN681568 : Shi, Zhan, Zhao, Wang, Ma: Effects of Fluoride on the Expression of p38MAPK Signaling Pathway-Related Genes and Proteins in Spleen Lymphocytes of Mice. in Biological trace element research 2016 (PubMed)


Human Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) interaction partners

  1. Data indicate that mitogen-activated protein kinase kinase 6 (MKK6) levels were substantially higher in monocytes than in neutrophils.

  2. Data show significant increase in the expression of MKK6 in Esophageal, Stomach, and Colon cancers as compared to controls.

  3. uncover a new mechanism of deactivation of MKK6-p38 (显示 CRK 抗体) and substantiate a novel regulatory role of FBXO31 (显示 FBXO5 抗体) in stress response

  4. Serine phosphorylation of p66shc (显示 SHC1 抗体) is carried out by active MKK6. beta-Amyloid-induced ROS (显示 ROS1 抗体) production and apoptosis increased in the presence of MKK6 and p66shc (显示 SHC1 抗体), which directly associate.

  5. The models confirmed the reaction order, revealed processivity in the phosphorylation of MEK6 by ASK1 (显示 MAP3K5 抗体), and suggested that the order of phosphorylation is dictated by both binding and catalysis rates.

  6. crystal structure of human non-phosphorylated MAP2K6 (npMAP2K6) complexed with an ATP analogue was determined at 2.6 A resolution and represents an auto-inhibition state of MAP2K6

  7. Data suggest aberrant MAP2K protein (MKK3 (显示 MAP2K3 抗体), MKK4 (显示 MAP2K4 抗体), MKK6, and MKK7 (显示 MAP2K7 抗体)) expression indicates that altered cellular signal transduction mediated via JNK (显示 MAPK8 抗体) and p38 (显示 CRK 抗体) may be common in bladder cancer.

  8. the balance between MKK6 and MKK3 (显示 MAP2K3 抗体) mediates p38 MAPK (显示 MAPK14 抗体) associated resistance to cisplatin in NSCLC

  9. activation by mechanical stretch induces HMGB1 (显示 HMGB1 抗体) and cytokine expression in A549 cells

  10. Results suggest that the p38alpha (显示 MAPK14 抗体), MAPK (显示 MAPK1 抗体), and MKK6 play prominent roles in IL-1beta (显示 IL1B 抗体) and C/EBP-beta (显示 CEBPB 抗体)-mediated C3 gene expression in astrocytes.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) interaction partners

  1. MKK3 (显示 MAP2K3 抗体) and MKK6 differentially regulate bone loss due to estrogen withdrawal. MKK3 (显示 MAP2K3 抗体) directly mediates osteoclastogenesis while MKK6 likely contributes to pro-inflammatory cytokine production that promotes osteoclast formation.

  2. Activation of distinct p38MAPK (显示 MAPK14 抗体) isoforms is regulated by the selective and synchronized action of two kinases, MKK3 (显示 MAP2K3 抗体) and MKK6, in response to cell stress.

  3. MKK6 is downreglated in peripheral CD4 (显示 CD4 抗体)(+)T cells

  4. p38alpha (显示 MAPK14 抗体) can negatively regulate the stability of the MKK6 mRNA and thus control the steady-state concentration of one of its upstream activators

  5. Involvement of MKK6 in apoptotic cell death in thymocytes.

  6. MKK6 is one of three different protein kinases which activate p38 MAPK (显示 MAPK14 抗体) in vitro.

  7. MKK3 (显示 MAP2K3 抗体) and MKK6 are rapidly activated during engagement of the Type I IFN receptor and play important roles in Type I IFN signaling and the generation of IFN responses

  8. increased activity of Sox9 (显示 SOX9 抗体) accounts at least in part for the phenotype caused by constitutive activation of MKK6 in chondrocytes

  9. These results indicate that TAK1 (显示 NR2C2 抗体) and MKK6 constitute the p38 (显示 CRK 抗体) signalling pathway to participate to Oc differentiation by RANKL (显示 TNFSF11 抗体) through p65 (显示 NFkBP65 抗体) phosphorylation and NFATc1 (显示 NFATC1 抗体) induction.

  10. All these results suggest that DGK (显示 DGUOK 抗体) may play a role in glucose transport in the skeletal muscle cells through modulating a MKK3 (显示 MAP2K3 抗体)/6-p38 (显示 CRK 抗体) signaling pathway.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6) interaction partners

  1. Arabidopsis MPK4 (显示 MAPK4 抗体) can interact with and be phosphorylated by the cytokinesis-related MAP kinase (显示 MAPK1 抗体) kinase, AtMKK6.

  2. AtMKK6-AtMPK13 (显示 MAPK1/3 抗体) module positively regulates lateral root formation.

  3. Plants with mutations in the MKK6/ANQ gene exhibit severe defects in cytokinesis.

MAP2K6 抗原简介

Antigen Summary

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Alternative names and synonyms associated with MAP2K6

  • mitogen-activated protein kinase kinase 6 (MAP2K6) 抗体
  • mitogen-activated protein kinase kinase 6 (Map2k6) 抗体
  • mitogen-activated protein kinase kinase 6 (MKK6) 抗体
  • mitogen-activated protein kinase kinase 6 (map2k6) 抗体
  • ANQ1 抗体
  • ATMKK6 抗体
  • map2k3 抗体
  • MAP kinase kinase 6 抗体
  • MAPKK6 抗体
  • MEK6 抗体
  • MIK19.2 抗体
  • MIK19_2 抗体
  • MKK3 抗体
  • Mkk6 抗体
  • Prkmk6 抗体
  • SAPKK-3 抗体
  • SAPKK3 抗体
  • zMKK3 抗体

Protein level used designations for MAP2K6

MAPK/ERK kinase 6 , MAPKK 6 , MEK 6 , SAPK kinase 3 , dual specificity mitogen-activated protein kinase kinase 6 , protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6) , stress-activated protein kinase kinase 3 , MAP kinase kinase 6 , mitogen activated protein kinase kinase 6 , protein kinase, mitogen activated, kinase 6 , mitogen-activated protein kinase kinase 3

5608 Homo sapiens
114495 Rattus norvegicus
26399 Mus musculus
286883 Bos taurus
417445 Gallus gallus
100355230 Oryctolagus cuniculus
100731419 Cavia porcellus
835759 Arabidopsis thaliana
65239 Danio rerio
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