anti-ABCC5 (ABCC5) 抗体产品概述

Full name:
anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 抗体 (ABCC5)
在www.antibodies-online.cn可供94 ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5) 抗体的16不同的供货商。 再加上,我们可以发ABCC5 试剂盒 (5)ABCC5 蛋白 (4)和数多这个蛋白质的别的产品。 总共106 ABCC5产品已列进来了。
别名:
2900011L11Rik, ABC33, Abcc5a, Abcc5b, AI132311, EG636260, EST277145, Gm7175, MOAT-C, MOATC, Mrp5, pABC11, SMRP

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引用最多的anti-ABCC5 抗体

  1. Human Monoclonal ABCC5 Primary Antibody for IHC (fro), IF - ABIN1105175 : Borst, de Wolf, van de Wetering: Multidrug resistance-associated proteins 3, 4, and 5. in Pflügers Archiv : European journal of physiology 2007 (PubMed)
    Show all 3 references for 1105175

  2. Human Monoclonal ABCC5 Primary Antibody for IHC (fro), IF - ABIN1105177 : Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997 (PubMed)
    Show all 2 references for 1105177

  3. Human Monoclonal ABCC5 Primary Antibody for IHC (fro), IF - ABIN1105176 : Scheffer, Kool, Heijn, de Haas, Pijnenborg, Wijnholds, van Helvoort, de Jong, Hooijberg, Mol, van der Linden, de Vree, van der Valk, Elferink, Borst, Scheper: Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. in Cancer research 2000 (PubMed)
    Show all 2 references for 1105176

  4. Human Polyclonal ABCC5 Primary Antibody for IHC (p), IHC - ABIN409071 : Meyer Zu Schwabedissen, Grube, Heydrich, Linnemann, Fusch, Kroemer, Jedlitschky et al.: Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ... in The American journal of pathology 2005 (PubMed)

  5. Human Polyclonal ABCC5 Primary Antibody for FACS, IHC (p) - ABIN652519 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

更多抗ABCC5的相互作用对抗体

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5) interaction partners

  1. These findings enrich the allelic spectrum of ABCC5 in PACG. We identified no tagging SNP responsible for the association of the whole region.

  2. Survivors of childhood acute lymphoblastic leukemia treated with doxorubicin with the ABCC5 TT-1629 genotype had an average of 8-12% reduction of ventricular ejection and shortening fractions.

  3. our work indicated that decreased SLC34A2 (显示 SLC34A2 抗体) expression sensitized BCSCs to doxorubicin via SLC34A2 (显示 SLC34A2 抗体)-Bmi1 (显示 BMI1 抗体)-ABCC5 signaling and shed new light on understanding the mechanism of chemoresistance in BCSCs. This study not only bridges the missing link between stem cell-related transcription factor (Bmi1 (显示 BMI1 抗体)) and ABC transporter (显示 ABCG2 抗体) (ABCC5) but also contributes to development of potential therapeutics against breast cancer.

  4. Deletions of ABCC5 predict good tumor response to neoadjuvant chemotherapy in breast cancer.

  5. genetic association study in population in Mexico: Data suggest SNPs in ABCC5 (3933+313T>C) are not associated with adverse reactions to methotrexate; they protect against myelosuppression in pediatric patients with ALL (acute lymphoblastic leukemia).

  6. We identified several genes (FasL (显示 FASL 抗体), MSH2 (显示 MSH2 抗体), ABCC5, CASP3 (显示 CASP3 抗体), and CYP3A4 (显示 CYP3A4 抗体))that showed association with PFS in patients with osteosarcoma. These pharmacogenetic risk factors might be useful to predict treatment outcome

  7. ABCC5 is a general glutamate (显示 GRIN1 抗体) conjugate and analog transporter that affects the disposition of endogenous metabolites, toxins, and drugs.

  8. The present study investigated the time course and dose dependency of the induction of three efflux proteins, P-gp (显示 ABCB4 抗体), MRP1 (显示 MDM4 抗体) and MRP5, in response to gemcitabine exposure in Capan-2 pancreatic cancer cell line at transcriptional and translational levels.

  9. cCMP is a substrate for MRP5

  10. The blockade of ABC transporter (显示 ABCG2 抗体) MRP5 could help to improve drug effectiveness, reduce tumour growth and prevent recurrence in glioblastoma multiforme.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5) interaction partners

  1. ABCC5 is a general glutamate (显示 GRIN1 抗体) conjugate and analog transporter that affects the disposition of endogenous metabolites, toxins, and drugs.

  2. Deficiency of MKP5 (显示 DUSP10 抗体) resulted in increased inflammatory activation in macrophages. These findings thus demonstrate that MKP5 (显示 DUSP10 抗体) critically controls inflammation in white adipose tissue and the development of metabolic disorders

  3. Reduced cGMP export as a consequence of decreased MRP5 expression can attenuate heart failure in sepsis.

ABCC5 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear.

Alternative names and synonyms associated with ABCC5

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (ABCC5) 抗体
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5) 抗体
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 5 (Abcc5) 抗体
  • immunoglobulin heavy variable 9-4 (Ighv9-4) 抗体
  • 2900011L11Rik 抗体
  • ABC33 抗体
  • Abcc5a 抗体
  • Abcc5b 抗体
  • AI132311 抗体
  • EG636260 抗体
  • EST277145 抗体
  • Gm7175 抗体
  • MOAT-C 抗体
  • MOATC 抗体
  • Mrp5 抗体
  • pABC11 抗体
  • SMRP 抗体

Protein level used designations for ABCC5

ATP-binding cassette sub-family C member 5 , canalicular multispecific organic anion transporter C , multi-specific organic anion transporter C , multidrug resistance-associated protein 5 , ATP-binding cassette, sub-family C (CFTR/MRP), member 5a , ATP-binding cassette, sub-family C (CFTR/MRP), member 5b , ATP-binding cassette, sub-family C, member 5 , MOAT-C , SMRP , ATP-binding cassette sub-family C (CFTR/MRP) member 5a , ATP-binding cassette, sub-family C (CFTR/MRP), member 5

GENE ID SPECIES
10057 Homo sapiens
27416 Mus musculus
116721 Rattus norvegicus
636260 Mus musculus
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