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抗Human MKRN1 抗体:
抗Rat (Rattus) MKRN1 抗体:
抗Mouse (Murine) MKRN1 抗体:
Human Polyclonal MKRN1 Primary Antibody for ICC, IF - ABIN188614
Ko, Lee, Yeh, Yang, Oh, Moon, Song: MKRN1 induces degradation of West Nile virus capsid protein by functioning as an E3 ligase. in Journal of virology 2009
Human Polyclonal MKRN1 Primary Antibody for ELISA, WB - ABIN4334837
Kim, Park, Kang, Oh, Lee, Muller, Chung: Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. in Genes & development 2005
In combination testing, MKRN1 + HPV showed the highest sensitivity and specificity levels. The MKRN1 biomarker may be a useful adjunct in primary cervical cytology screening.
EGFR (显示 EGFR 抗体)/PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体)-mediated ubiquitination and degradation of PTEN (显示 PTEN 抗体) are dependent on the MKRN1 E3 ligase.
Results verified MKRN1 as an ubiquitin E3 ligase of p14ARF (显示 CDKN2A 抗体), it potentially regulates cellular aging and tumorigenesis in gastric cancer.
MKRN1 could induce WNV capsid protein ubiquitination and degradation in a proteasome-dependent manner
MKRN1 may represent a nuclear protein with multiple nuclear functions, including regulating RNA polymerase II-catalyzed transcription.
Data indicate that MKRN1 is a novel modulator of p53 (显示 TP53 抗体) and p21 (显示 CDKN1A 抗体), preferentially leading cells to p53 (显示 TP53 抗体)-dependent apoptosis by suppressing p21 (显示 CDKN1A 抗体).
Makorin 1 is a novel SEREX antigen of esophageal squamous cell carcinoma
Systems-level analyses support a role for the E3 ligase MKRN1 as a ribonucleoprotein within the embryonic stem cell gene regulatory network
MKRN1 is an elusive PPARgamma (显示 PPARG 抗体) E3 ligase that targets PPARgamma (显示 PPARG 抗体) for proteasomal degradation by ubiquitin-dependent pathways, and further depict MKRN1 as a novel target for diseases involving PPARgamma (显示 PPARG 抗体).
Mutagenesis reduces transcription of Makorin1-pseudogene, resulting in destabilization of Makorin1 mRNA in trans by way of a cis (显示 CISH 抗体)-acting RNA decay element within the 5' region of Makorin1 that is homologous between Makorin1 and Makorin1-pseudogene
Mkrn1-p1 is not imprinted, and neither it or its source Mkrn1 gene relates to the original imprinted transgene phenotype
The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000
makorin ring finger protein 1
, makorin, ring finger protein, 1
, E3 ubiquitin-protein ligase makorin-1-like
, e3 ubiquitin-protein ligase makorin-1-like
, MGC84269 protein
, makorin 1
, E3 ubiquitin-protein ligase makorin-1
, RING finger protein 61