Angiomotin (AMOT) ELISA试剂盒产品概述

Full name:
Angiomotin ELISA试剂盒 (AMOT)
在www.antibodies-online.cn可供24 Angiomotin (AMOT) ELISA试剂盒的8不同的供货商。 再加上,我们可以发Angiomotin 抗体 (98)Angiomotin 蛋白 (5)和数多这个蛋白质的别的产品。 总共139 Angiomotin产品已列进来了。
别名:
AMOTL2, C81439, CAG-2, D0Kist1, E230009N18Rik, mKIAA1071, RGD1564027, si:dkey-13f9.6, Sii6, wu:fj21a07

适于 Angiomotin 相互作用对的更多 ELISA 试剂盒

Cow (Bovine) Angiomotin (AMOT) interaction partners

  1. Amot and AmotL1 (显示 AMOTL1 ELISA试剂盒) have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot appears to control the cell polarity and AmotL1 (显示 AMOTL1 ELISA试剂盒) affects the stability of cell-cell junctions.

Zebrafish Angiomotin (AMOT) interaction partners

  1. Thus AMOT is a direct substrate of Lats1/2 mediating functions of the Hippo pathway in endothelial cell migration and angiogenesis.

  2. knockdown of Amot reduced the number of filopodia of endoth (显示 PDPN ELISA试剂盒)elial tip cells and severely impaired the migration of intersegmental vessels

  3. Amot and AmotL1 (显示 AMOTL2 ELISA试剂盒) have similar effects on endothelial migration and tight junction formation in vitro. In vivo Amot appears to control the cell polarity and AmotL1 (显示 AMOTL2 ELISA试剂盒) affects the stability of cell-cell junctions.

Human Angiomotin (AMOT) interaction partners

  1. AMOT may function as an oncogene (显示 RAB1A ELISA试剂盒) in the progression of colon cancer by activating the YAP (显示 YAP1 ELISA试剂盒)-ERK (显示 EPHB2 ELISA试剂盒)/PI3K (显示 PIK3CA ELISA试剂盒)-AKT (显示 AKT1 ELISA试剂盒) signaling pathway.

  2. The lncRNA SNHG12 promotes cell proliferation and migration by upregulating AMOT gene expression in osteosarcoma cells in vivo and in vitro.

  3. angiomotin and Merlin respectively interface cortical actin filaments and core kinases in Hippo signaling

  4. Study shows miR (显示 MLXIP ELISA试剂盒)-205 significantly downregulated and directly target the 3'-UTR (显示 UTS2R ELISA试剂盒) of AMOT in breast cancer. In vitro, miR (显示 MLXIP ELISA试剂盒)-205 regulates the proliferation and invasion of breast cancer cells through suppression of AMOT expression.

  5. Amot was highly expressed in breast cancer tissues and was important in the promotion of breast cancer cell proliferation and invasion. Amot knockdown in MCF-7 cells decreased the expression of YAP, YAP/TAZ and LATS1.

  6. experiments indicate that AMOT and other motin family members function together with NEDD4L to help complete immature virion assembly prior to ESCRT-mediated virus budding

  7. AMOT is a crucial suppressor of lung cancer metastasis and highlight its critical role as a tumor suppressor and its potential as a prognostic biomarker and therapeutic target for lung cancer.

  8. angiomotin proteins connect F-actin architecture to YAP (显示 YAP1 ELISA试剂盒) regulation.

  9. Scaffold proteins angiomotin (Amot) and angiomotin-related AmotL1 (显示 AMOTL1 ELISA试剂盒) and AmotL2 (显示 AMOTL2 ELISA试剂盒) were recently identified as negative regulators of YAP (显示 YAP1 ELISA试剂盒) and TAZ (显示 TAZ ELISA试剂盒) by preventing their nuclear translocation.

  10. Within the nucleus, Amot-p130 (显示 RBL2 ELISA试剂盒) was associated with the transcriptional complex containing Yap (显示 YAP1 ELISA试剂盒) and Teads (TEA domain family members) and contributed to the regulation of a subset of Yap (显示 YAP1 ELISA试剂盒) target genes, many of which are associated with tumorigenesis.

Mouse (Murine) Angiomotin (AMOT) interaction partners

  1. a new function of RNF146 (显示 RNF146 ELISA试剂盒) and tankyrase in stabilizing the Crumbs complex through downregulation of AMOT proteins at the apical membrane, is reported.

  2. AMOT is a crucial suppressor of lung cancer metastasis and highlight its critical role as a tumor suppressor and its potential as a prognostic biomarker and therapeutic target for lung cancer.

  3. Within the nucleus, Amot-p130 was associated with the transcriptional complex containing Yap (显示 YAP1 ELISA试剂盒) and Teads (TEA domain family members) and contributed to the regulation of a subset of Yap (显示 YAP1 ELISA试剂盒) target genes, many of which are associated with tumorigenesis.

  4. The loss of Angiomotin, together with Angiomotin-like 2 (显示 AMOTL2 ELISA试剂盒), leads to differentiation of inner cell mass cells and compromised peri (显示 POSTN ELISA试剂盒)-implantation development.

  5. The phosphorylation of S176 in the N-terminal domain of Amot is a critical step for activation of the Hippo pathway in adherens junctions and cell polarity disconnects the Hippo pathway from cell-cell adhesion by sequestering Amot from AJs.

  6. Amot, Amotl1 (显示 AMOTL1 ELISA试剂盒), and Amotl2 (显示 AMOTL2 ELISA试剂盒) are differentially expressed in uterine cells during the peri (显示 POSTN ELISA试剂盒)-implantation period.

  7. A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors.

  8. Depletion of Angiomotin in Nf2 (显示 NF2 ELISA试剂盒)(-/-) Schwann cells attenuates the Ras-MAPK (显示 MAPK1 ELISA试剂盒) signaling pathway, impedes cellular proliferation in vitro and tumorigenesis in vivo

  9. Angiomotin may promote neoplastic angiogenesis by both stimulating invasion as well as stabilizing established tubes.

  10. angiomotin, in addition to controlling cell motility, may play a role in the assembly of endothelial cell-cell junctions

Angiomotin (AMOT) 抗原简介

Antigen Summary

This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.

Alternative names and synonyms associated with Angiomotin (AMOT)

  • angiomotin (AMOT) Elisa Kit
  • angiomotin like 2 (AMOTL2) Elisa Kit
  • angiomotin (amot) Elisa Kit
  • angiomotin (Amot) Elisa Kit
  • AMOTL2 Elisa Kit
  • C81439 Elisa Kit
  • CAG-2 Elisa Kit
  • D0Kist1 Elisa Kit
  • E230009N18Rik Elisa Kit
  • mKIAA1071 Elisa Kit
  • RGD1564027 Elisa Kit
  • si:dkey-13f9.6 Elisa Kit
  • Sii6 Elisa Kit
  • wu:fj21a07 Elisa Kit

Protein level used designations for Angiomotin (AMOT) ELISA试剂盒

angiomotin like 2 , angiomotin-like protein 2 , angiomotin-like protein 2-like , angiomotin p130 isoform , angiomotin p80 isoform

GENE ID SPECIES
100054069 Equus caballus
424863 Gallus gallus
485669 Canis lupus familiaris
538514 Bos taurus
563421 Danio rerio
100402195 Callithrix jacchus
422336 Gallus gallus
154796 Homo sapiens
481022 Canis lupus familiaris
27494 Mus musculus
300289 Rattus norvegicus
100158213 Sus scrofa
535509 Bos taurus
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