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Human Monoclonal CXCL1 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900741
Meen, Øynebråten, Reine, Duelli, Svennevig, Pejler, Jenssen, Kolset: Serglycin is a major proteoglycan in polarized human endothelial cells and is implicated in the secretion of the chemokine GROalpha/CXCL1. in The Journal of biological chemistry 2011
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Human Monoclonal CXCL1 Primary Antibody for CyTOF, ELISA (Capture) - ABIN4900740
Oladipo, Conlon, OGrady, Purcell, Wilson, Maxwell, Johnston, Stevenson, Kay, Wilson, Waugh: The expression and prognostic impact of CXC-chemokines in stage II and III colorectal cancer epithelial and stromal tissue. in British journal of cancer 2011
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Human Polyclonal CXCL1 Primary Antibody for WB - ABIN3044150
Xu, Zhu, Zhang, Tian, Zhang, Wu, Gao: NF?B-mediated CXCL1 production in spinal cord astrocytes contributes to the maintenance of bone cancer pain in mice. in Journal of neuroinflammation 2014
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Human Polyclonal CXCL1 Primary Antibody for IHC, IHC (p) - ABIN4316223
Yeh, Shun, Kuo, Jung, Hsieh, Chiu, Chen, Hsu, Yang, Chia: Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis. in Infection and immunity 2015
Mouse (Murine) Polyclonal CXCL1 Primary Antibody for IF (p), IHC (p) - ABIN2173443
Ito, Katano, Kawai, Yagoto, Takahashi, Ka, Ogura, Takahashi, Ito: A Novel Xenogeneic Graft-Versus-Host Disease Model for Investigating the Pathological Role of Human CD4(+) or CD8(+) T Cells Using Immunodeficient NOG Mice. in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2016
Rat (Rattus) Polyclonal CXCL1 Primary Antibody for Func, ELISA - ABIN2473131
Vallès, Grijpink-Ongering, de Bree, Tuinstra, Ronken: Differential regulation of the CXCR2 chemokine network in rat brain trauma: implications for neuroimmune interactions and neuronal survival. in Neurobiology of disease 2006
Human Polyclonal CXCL1 Primary Antibody for ELISA - ABIN4274952
Kawanishi, Matsui, Ito, Watanabe, Takahashi, Nishizawa, Nishiyama, Kamoto, Mikami, Tanaka, Jung, Akiyama, Nobumasa, Guilford, Reeve, Okuno, Tsujimoto, Nakamura, Ogawa: Secreted CXCL1 is a potential mediator and marker of the tumor invasion of bladder cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008
this study demonstrates that in vivo blocking of CXCL1 and CXCL2 (显示 CXCL2 抗体) can significantly reduce the Mycobacterium tuberculosis-induced bioactive IL-1beta (显示 IL1B 抗体) production
RelA (显示 NFkBP65 抗体) has a role in regulating OIS in preneoplastic lesions; the RelA (显示 NFkBP65 抗体)/CXCL1/CXCR2 (显示 CXCR2 抗体) axis is an essential mechanism of tumor surveillance in pancreatic ductal adenocarcinoma
CXCL1 contributed to rapid neutrophil recruitment during Bacillus cereus endophthalmitis. In CXCL1-knockout mice, retinal function was greater and neutrophil influx was less than in control mice, confirming its role in ocular inflammation.
Interferon-gamma (IFN-gamma (显示 IFNG 抗体)) up-regulated interleukin 6 (IL-6 (显示 IL6 抗体)) and CXCL1 chemokine (显示 CCL1 抗体) (CXCL1) production of bone marrow mesenchymal stem cells (mBM-MSC (显示 MSC 抗体)).
MMP7 (显示 MMP7 抗体) shedding of syndecan-1 (显示 SDC1 抗体)/CXCL1 complexes functions as a checkpoint that restricts neutrophil activation at sites of epithelial injury.
Data show that loss of loss of matrix metalloproteinase-3 (MMP-3 (显示 MMP3 抗体)) repressed the upregulation of the chemokines monocyte chemoattractant protein (MCP)-1 (显示 CPT1B 抗体) and (C-X-C motif) ligand 1 (CXCL1).
CXCR2 (显示 CXCR2 抗体)/CXCL1 axis promotes granulocytic myeloid-derived suppressor cells recruitment and facilitates arginase I (显示 ARG1 抗体) expression and activity of these cells at maternal-fetal interface
The novel findings reveal the critical role of NLRP12 (显示 NLRP12 抗体)-IL-17A (显示 IL17A 抗体)-CXCL1 axis in host defense by modulating neutrophil recruitment against Klebsiella pneumoniae.
Nlrp12 (显示 NLRP12 抗体) deficiency caused increased neutrophil migration towards the chemokine (显示 CCL1 抗体) CXCL1 and the neutrophil parasite Leishmania major, revealing NLRP12 (显示 NLRP12 抗体) as a negative regulator of directed neutrophil migration under these conditions.
CXCL1 monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 (显示 CXCR2 抗体) activation
Taken together, the present study indicates that IL-33 (显示 IL33 抗体) localized in the human atherosclerotic plaque increases GRO-alpha mRNA expression and protein secretion via activation of ERK1/2 (显示 MAPK1/3 抗体), JNK (显示 MAPK8 抗体), and NF-kappaB (显示 NFKB1 抗体) in HUVECs, suggesting that IL-33 (显示 IL33 抗体) plays an important role in the pathophysiology and development of atherosclerosis.
Study provides the first evidence that primary malignant cell-secreted VEGFA (显示 VEGFA 抗体) stimulates tumor-associated macrophages to produce CXCL1, which recruits CXCR2 (显示 CXCR2 抗体)-positive MDSCs to form a premetastatic niche to promote liver metastases.
the presence of elevated circulating levels of VEGF (显示 VEGFA 抗体) and CXCL1 are predictive of liver and lung metastasis, respectively of colorectal cancer.
This study describe elevated levels of CXCL1 and it receptor in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma, relative to other pediatric brain tumors and normal cerebral tissue.
The expressions of CXCL1 in cancer cells and CXCR2 (显示 CXCR2 抗体) in stromal cells are useful prognostic factors for gastric cancer patients
CXCL1 secreted by tumor-associated lymphatic endothelial cells promotes lymph node metastasis of gastric cancer through integrin beta1/FAK (显示 PTK2 抗体)/AKT (显示 AKT1 抗体) signaling pathway.
S100A9 (显示 S100A9 抗体) and S100A12 (显示 S100A12 抗体) may have a role in the pathogenesis of pneumonia: S100A9 (显示 S100A9 抗体) and CXCL1 may contribute solely in mild pneumonia, and CCL5 (显示 CCL5 抗体) and CXCL11 (显示 CXCL11 抗体) may contribute in severe pneumonia.
These findings support a role for CXCL1 and IL-8 (显示 IL8 抗体) in cystic fibrosis (显示 S100A8 抗体) lung disease severity and identify STAT3 (显示 STAT3 抗体) as a modulating pathway.
Results suggest that CXCL1 is a key molecular link between senescence of stromal fibroblasts and tumor growth.
Increased IL-8 (显示 IL8 抗体) and CXCL1 transcription in T84 and THP-1 (显示 GLI2 抗体) cells compared to that in wild-type EPEC.
This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
, growth-regulated alpha protein
, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
, melanoma growth stimulatory activity homolog
, C-X-C motif chemokine 1
, cytokine-induced neutrophil chemoattractant 1
, platelet-derived growth factor-inducible protein KC
, GRO1 oncogene
, secretory protein N51
, growth regulated protein GRO
, growth regulated
, GRO1 oncogene (melanoma growth stimulating activity, alpha)
, GRO1 oncogene (melanoma growth-stimulating activity)
, MGSA alpha
, fibroblast secretory protein
, melanoma growth stimulatory activity alpha
, neutrophil-activating protein 3
, growth related gene 1
, growth-regulated protein homolog alpha