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Our results indicate that TRIM25 (显示 TRIM25 ELISA试剂盒) is associated with cisplatin resistance and 14-3-3sigma-MDM2 (显示 MDM2 ELISA试剂盒)-p53 (显示 TP53 ELISA试剂盒) signaling pathway is involved in this process, suggesting targeting TRIM25 (显示 TRIM25 ELISA试剂盒) may be a potential strategy for the reversal of cisplatin resistance.
Up-regulation of 14-3-3zeta (显示 YWHAZ ELISA试剂盒) in response to pVHL (显示 VHL ELISA试剂盒) is important for the recruitment of PI3K (显示 PIK3CA ELISA试剂盒) to the cell membrane and for stabilization of soluble beta-catenin (显示 CTNNB1 ELISA试剂盒).
The 14-3-3 family is dysregulated in schizophrenia, perhaps owing to specific regulatory mechanisms; the expression of the 14-3-3 epsilon (显示 YWHAE ELISA试剂盒), theta and zeta isoforms could be useful indicators of disease severity.
High urine 14-3-3 expression is associated with Advanced Stage in Patients with Clear Cell Renal Cell Carcinoma.
Levels of 14-3-3 protein (显示 YWHAE ELISA试剂盒) predict poorer radiographic outcomes in inflammatory polyarthritis patients.
Study shows that 14-3-3 zeta (显示 YWHAZ ELISA试剂盒)/delta is important in the extracellular vesicles mediated induction of colon malignant phenotype, suggesting its role as a potential target for therapeutic interventions.
the effects of cell viability, migration and invasion were mediated in 14-3-3zeta (显示 YWHAZ ELISA试剂盒)-dependent manner while that of cell apoptosis was mediated in 14-3-3zeta (显示 YWHAZ ELISA试剂盒)-independent manner.
14-3-3zeta (显示 YWHAZ ELISA试剂盒) reduces DNA damage by interacting with and stabilizing proliferating cell nuclear antigen (显示 PCNA ELISA试剂盒)
phosphorylation of HS1 (显示 EEF1A2 ELISA试剂盒) tyrosines at positions 222, 378 and 397 was required for transendothelial migration of NK cells.
Mimitin and 14-3-3 protein zeta/delta (显示 YWHAZ ELISA试剂盒) are potential markers of paclitaxel resistance and prognostic factors in ovarian cancer.
analysis of phosphorylation-dependent interactions of AQP2 (显示 AQP2 ELISA试剂盒) with 14-3-3theta; and -zeta
Data show that IkappaB kinase (显示 CHUK ELISA试剂盒) (IKK (显示 CHUK ELISA试剂盒)) phosphorylation of the TPL-2 (显示 MAP3K8 ELISA试剂盒) kinase (TPL-2 (显示 MAP3K8 ELISA试剂盒)) induces 14-3-3 association with TPL-2 (显示 MAP3K8 ELISA试剂盒), stimulating its MEK (显示 MDK ELISA试剂盒) kinase activity, which is essential for TPL-2 (显示 MAP3K8 ELISA试剂盒) activation of ERK-1 (显示 MAPK3 ELISA试剂盒)/2.
There is a scaffolding role for 14-3-3theta in assisting the delivery of Cx43 (显示 GJA1 ELISA试剂盒) and integrin alpha5 to the plasma membrane for the formation of mechanosensitive hemichannels in osteocytes.
14-3-3 negatively regulates the RGC downstream of the PI3-kinase (显示 PIK3CA ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒) signaling pathway
14-3-3 theta is a new and important regulatory protein (显示 TGFB1 ELISA试剂盒) in the TLR-2 (显示 TLR2 ELISA试剂盒) and TLR-4 (显示 TLR4 ELISA试剂盒) signaling suppressing the MyD88 (显示 MYD88 ELISA试剂盒)-dependent pathway
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease.
14-3-3 protein tau
, 14-3-3 tau
, 14-3-3 theta
, 14-3-3 protein theta
, 14-3-3 protein T-cell
, tyrosine 3/tryptophan 5 -monooxygenase activation protein, theta polypeptide
, cerebellar 14-3-3 theta protein
, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 2