anti-CYLD (CYLD) 抗体产品概述

Full name:
anti-Cylindromatosis (Turban Tumor Syndrome) 抗体 (CYLD)
在www.antibodies-online.cn可供79 Cylindromatosis (Turban Tumor Syndrome) (CYLD) 抗体的18不同的供货商。 再加上,我们可以发CYLD 试剂盒 (9)CYLD 蛋白 (8)和数多这个蛋白质的别的产品。 总共99 CYLD产品已列进来了。
2010013M14Rik, 2900009M21Rik, BRSS, C130039D01Rik, CDMT, cyld, CYLD1, CYLDI, EAC, LRRGT00003, MFT, MFT1, mKIAA0849, Rp1, Rp1h, SBS, TEM, USPL2

最受欢迎的抗anti-CYLD (CYLD) 抗体


抗Rat (Rattus) CYLD 抗体:

抗Mouse (Murine) CYLD 抗体:

抗Human CYLD 抗体:

所有可销售的anti-CYLD 抗体


引用最多的anti-CYLD 抗体

  1. Mouse (Murine) Polyclonal CYLD Primary Antibody for ELISA, WB - ABIN188848 : Massoumi, Chmielarska, Hennecke, Pfeifer, Fässler: Cyld inhibits tumor cell proliferation by blocking Bcl-3-dependent NF-kappaB signaling. in Cell 2006 (PubMed)

  2. Human Polyclonal CYLD Primary Antibody for ICC, IF - ABIN252428 : Moranta, Regueiro, March, Llobet, Margareto, Larrarte, Larrate, Garmendia, Bengoechea: Klebsiella pneumoniae capsule polysaccharide impedes the expression of beta-defensins by airway epithelial cells. in Infection and immunity 2010 (PubMed)


Zebrafish Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. The crystal structures representing the catalytic states of zebrafish CYLD for Met1 (显示 DNMT1 抗体)- and Lys63-linked Ub chains and two distinct precatalytic states for Met1 (显示 DNMT1 抗体)-linked chains are presented.

Mouse (Murine) Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. TLR4 (显示 TLR4 抗体) activates CASPASE-8 (显示 CASP8 抗体) to cleave and remove the deubiquitinase cylindromatosis (CYLD) in a TRIF (显示 RNF138 抗体)- and RIPK1 (显示 RIPK1 抗体)-dependent manner to disable necroptosis in macrophages.

  2. CYLD contributes to the transdifferentiation of adventitial fibroblasts via deubiquitinating Nox4 (显示 NOX4 抗体) and may play a role in vascular remodeling.

  3. this study shows that by polarization of the T cell cytokine response, CYLD can favor the development of allergic airway disease

  4. Our findings underscore a critical tumor-suppressing role for functional intestinal epithelial CYLD in colitis-associated carcinogenesis

  5. Deubiquitinase CYLD negatively regulates MyD88 (显示 MYD88 抗体)-mediated signaling by directly interacting with MyD88 (显示 MYD88 抗体) and deubiquitinating nontypeable Haemophilus influenzae (NTHi)-induced K63-linked polyubiquitination of MyD88 (显示 MYD88 抗体) at lysine 231.

  6. CYLD interrupts the ERK (显示 EPHB2 抗体)- and p38 (显示 CRK 抗体)-/AP-1 (显示 JUN 抗体) and c-Myc (显示 MYC 抗体) pathways to suppress Nrf2 (显示 NFE2L2 抗体)-operated antioxidative capacity, thereby enhancing oxidative stress in the heart.

  7. Our data demonstrate that inefficient negative selection in the thymus of CYLD(ex7/8) mice result from a defect in mTEC maturation.

  8. The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells.

  9. Data show that the in utero death of NF-NF (显示 NFASC 抗体)-kappaB (显示 NFKB1 抗体) essential modulator (NEMO (显示 IKBKG 抗体)) and cylindromatosis protein double mutant mice is mediated by TNF (显示 TNF 抗体) receptor 1 (TNFR1 (显示 TNFRSF1A 抗体)) signaling and can be rescued by TNFR1 (显示 TNFRSF1A 抗体) deficiency.

  10. CYLD is a central regulator of apoptotic cell death in murine hepatocytes by controlling NF-kappaB (显示 NFKB1 抗体) dependent anti-apoptotic signaling.

Human Cylindromatosis (Turban Tumor Syndrome) (CYLD) interaction partners

  1. The data reveal SPATA2 (显示 SPATA2 抗体) as a high-affinity binding partner of CYLD and HOIP (显示 RNF31 抗体), and a regulatory component of linear ubiquitin chain assembly complex-mediated NF-kappaB (显示 NFKB1 抗体) signaling.

  2. The current investigations identified a subset of HPV-positive HNSCCs with mutations in the genes TRAF3 (显示 TRAF3 抗体) (tumor necrosis factor (显示 TNF 抗体) receptor-associated factor 3) and CYLD (cylindromatosis lysine 63 deubiquitinase). Defects in TRAF3 (显示 TRAF3 抗体) and CYLD correlated with the activation of transcriptional factor nuclear factor kappaB, episomal HPV status of tumors, and improved patient survival.

  3. The predicted PUB domain in the N-terminus of SPATA2 interacts with the USP domain of CYLD and SPATA2 is required for recruitment of CYLD to the TNF-alpha receptor-associated signaling complexes.

  4. STAT3 (显示 STAT3 抗体) and miR (显示 MLXIP 抗体)-181b control each other's expression in a positive feedback loop that regulates SFCs via CYLD pathway.

  5. CYLD Promotes TNF-alpha (显示 TNF 抗体)-Induced Cell Necrosis Mediated by RIP-1 (显示 UQCRFS1 抗体) in Human Lung Cancer Cells

  6. Low CYLD expression is associated with hepatocellular carcinoma.

  7. miR20a directly repressed the expression of CYLD, leading to activation of the NFkappaB (显示 NFKB1 抗体) pathway and the downstream targets, livin (显示 BIRC7 抗体) and survivin (显示 BIRC5 抗体), which potentially induced GC chemoresistance.

  8. Data show that cylindromatosis (CYLD) overexpression and livin (显示 BIRC7 抗体) knockdown might improve gemcitabine chemosensitivity by decreasing autophagy and increasing apoptosis in bladder cancer (BCa (显示 BLNK 抗体)) cells.

  9. aberrantly expressed miR (显示 MLXIP 抗体)-130b may regulate cell apoptosis and proliferation of human gastric cancer cells via CYLD, which appears to be a promising therapeutic target for gastric cancer

  10. These results demonstrate the involvement of histone deacetylases in the down regulation of Cyld expression in hepatocellular carcinoma cells.

CYLD 抗原简介

Antigen Summary

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternative names and synonyms associated with CYLD

  • cylindromatosis (turban tumor syndrome) (CYLD) 抗体
  • cylindromatosis (turban tumor syndrome), a (cylda) 抗体
  • ubiquitin carboxyl-terminal hydrolase CYLD (LOC100362727) 抗体
  • cylindromatosis (turban tumor syndrome) (Cyld) 抗体
  • 2010013M14Rik 抗体
  • 2900009M21Rik 抗体
  • BRSS 抗体
  • C130039D01Rik 抗体
  • CDMT 抗体
  • cyld 抗体
  • CYLD1 抗体
  • CYLDI 抗体
  • EAC 抗体
  • LRRGT00003 抗体
  • MFT 抗体
  • MFT1 抗体
  • mKIAA0849 抗体
  • Rp1 抗体
  • Rp1h 抗体
  • SBS 抗体
  • TEM 抗体
  • USPL2 抗体

Protein level used designations for CYLD

cylindromatosis (turban tumor syndrome) , probable ubiquitin carboxyl-terminal hydrolase CYLD-like , ubiquitin carboxyl-terminal hydrolase CYLD , deubiquitinating enzyme CYLD , ubiquitin thioesterase CYLD , ubiquitin thiolesterase CYLD , ubiquitin-specific-processing protease CYLD , probable ubiquitin carboxyl-terminal hydrolase CYLD , retinitis pigmentosa 1 homolog , ubiquitin specific peptidase like 2

100050308 Equus caballus
556823 Danio rerio
100467467 Ailuropoda melanoleuca
100547998 Meleagris gallopavo
100362727 Rattus norvegicus
74256 Mus musculus
312937 Rattus norvegicus
1540 Homo sapiens
611649 Canis lupus familiaris
536421 Bos taurus
415725 Gallus gallus
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