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KSHVORF62 抗体

适用: Human Herpesvirus 8 (HHV-8) WB, ELISA, IHC 宿主: 小鼠 Monoclonal 5B7B6 unconjugated
产品编号 ABIN969255
发货至: 中国
  • 抗原
    KSHVORF62
    适用
    Human Herpesvirus 8 (HHV-8)
    宿主
    • 1
    小鼠
    克隆类型
    • 2
    单克隆
    标记
    • 2
    非结合性
    应用范围
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human KSHV ORF62 expressed in E. coli.
    克隆位点
    5B7B6
    亚型
    IgM
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Holyfield: "Spit Tobacco Prevention Network (STOPN)." in: Texas nursing, Vol. 74, Issue 10, pp. 9, (2002) (PubMed).

    Wu, Lo, Yu, Stoops, Forghani, Zhou: "Three-dimensional structure of the human herpesvirus 8 capsid." in: Journal of virology, Vol. 74, Issue 20, pp. 9646-54, (2000) (PubMed).

    Nakamura, Oguri, Tabe, Igari: "[Epidemiological study on Staphylococcus epidermidis isolated from bloodstream and blood vessel catheter]." in: Kansenshōgaku zasshi. The Journal of the Japanese Association for Infectious Diseases, Vol. 74, Issue 2, pp. 96-103, (2000) (PubMed).

  • 抗原
    KSHVORF62
    物质类
    Viral Protein
    背景

    Description: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. At least five major proteins are likely to be involved in the assembly of the HHV-8 capsid, including a protease (encoded by ORF17), the major capsid protein (encoded by ORF25), and three other smaller capsid proteins (encoded by ORF62, ORF26, and ORF65). Previous structural studies have shown that the HSV-1 triplex is a monomer of VP19c and a dimer of VP23 and that the HCMV triplex is similarly composed of a monomer and a dimer. By analogy, the KSHV triplexes are likely also composed of a monomer of the ORF62 protein and a dimer of the ORF26 protein, which are the respective homologs of VP19c and VP23.

    Aliases: ORF62

    基因ID
    4961461
    HGNC
    4961461
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