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KDM3A 抗体

KDM3A 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1-00E-12 unconjugated
产品编号 ABIN969228
发货至: 中国
  • 抗原 See all KDM3A 抗体
    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
    适用
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    宿主
    • 31
    • 15
    小鼠
    克隆类型
    • 31
    • 15
    单克隆
    标记
    • 31
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    This KDM3A antibody is un-conjugated
    应用范围
    • 37
    • 23
    • 21
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human KDM3A expressed in E. coli.
    克隆位点
    1-00E-12
    亚型
    IgG1
    Top Product
    Discover our top product KDM3A Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, (2005) (PubMed).

    Nagase, Ishikawa, Suyama, Kikuno, Miyajima, Tanaka, Kotani, Nomura, Ohara: "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 5, pp. 277-86, (1999) (PubMed).

  • 抗原
    KDM3A (Lysine (K)-Specific Demethylase 3A (KDM3A))
    别名
    KDM3A (KDM3A 产品)
    别名
    JHDM2A antibody, JHMD2A antibody, JMJD1 antibody, JMJD1A antibody, TSGA antibody, tsga antibody, jmjd1 antibody, jhdm2a antibody, jhmd2a antibody, jmjd1a antibody, 1700105C21Rik antibody, C230043E16Rik antibody, JHDM2a antibody, Jmjd1 antibody, Jmjd1a antibody, KDM2A antibody, TGSA antibody, Tsga antibody, mKIAA0742 antibody, KDM3A antibody, kdm3a antibody, lysine demethylase 3A antibody, lysine (K)-specific demethylase 3A antibody, lysine-specific demethylase 3A antibody, lysine (K)-specific demethylase 3A S homeolog antibody, KDM3A antibody, kdm3a antibody, Kdm3a antibody, LOC100453519 antibody, kdm3a.S antibody
    背景

    Description: This gene encodes a zinc finger protein that contains a jumonji domain and may play a role in hormone-dependent transcriptional activation. JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and α-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.

    Aliases: TSGA, JMJD1, JHDM2A, JHMD2A, JMJD1A, KIAA0742, DKFZp686A24246, DKFZp686P07111, KDM3A

    分子量
    147 kDa
    基因ID
    55818
    HGNC
    55818
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Warburg Effect
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