Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
预测反应
B, M, Rat
纯化方法
This antibody is purified through a protein A column, followed by peptide affinity purification.
免疫原
This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human RASGRP2.
CALDAG-GEFI antibody, CDC25L antibody, xrasgrp2 antibody, RASGRP2 antibody, Caldaggef1 antibody, CalDAG-GEFI antibody, rasgrp2 antibody, RAS guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog antibody, RAS, guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog antibody, RASGRP2 antibody, rasgrp2.S antibody, Rasgrp2 antibody, rasgrp2.L antibody
背景
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.