KCNMB4 抗体 (Middle Region)
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- 抗原 See all KCNMB4 抗体
- KCNMB4 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 4 (KCNMB4))
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抗原表位
- Middle Region
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNMB4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 特异性
- KCNMB4 antibody was raised against the middle region of KCNMB4
- 纯化方法
- Affinity purified
- 免疫原
- KCNMB4 antibody was raised using the middle region of KCNMB4 corresponding to a region with amino acids TCGADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCK
- Top Product
- Discover our top product KCNMB4 Primary Antibody
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- 应用备注
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
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KCNMB4 Blocking Peptide, catalog no. 33R-8994, is also available for use as a blocking control in assays to test for specificity of this KCNMB4 antibody
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of KCNMB4 antibody in PBS
- 浓度
- Lot specific
- 缓冲液
- PBS
- 注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- 抗原
- KCNMB4 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, beta Member 4 (KCNMB4))
- 别名
- KCNMB4 (KCNMB4 产品)
- 别名
- 1700058G18Rik antibody, 2900045G12Rik antibody, kcnmb4 antibody, potassium calcium-activated channel subfamily M regulatory beta subunit 4 antibody, potassium large conductance calcium-activated channel, subfamily M, beta member 4 antibody, potassium channel subfamily M regulatory beta subunit 4 antibody, Kcnmb4 antibody, KCNMB4 antibody, kcnmb4 antibody
- 背景
- KCNMB4 is the regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. KCNMB4 modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. KCNMB4 decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. KCNMB4 may decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. KCNMB4 makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.
- 分子量
- 24 kDa (MW of target protein)
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