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小鼠 anti-人 IgG (Fc Region) Antibody

ABIN614786 产品详细信息, 供应商: Log in to see
抗原
抗原表位
Fc Region
4763
2573
1886
1055
1007
843
304
273
35
34
31
8
7
7
3
3
2
2
1
1
1
1
1
1
适用

2817
2784
2375
1734
1463
781
607
425
365
338
331
324
307
290
169
148
126
114
41
29
27
25
12
11
9
8
6
5
5
4
4
4
4
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
宿主
小鼠
6775
4670
1876
825
703
396
88
54
52
21
9
8
5
5
2
1
1
克隆类型 (克隆位点)
单克隆 ()
应用范围
Immunofluorescence (IF)
Supplier
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免疫原 Fusion protein of human IgG Fc fragment
克隆位点 EM-07
亚型 IgG1
交叉反应 (详细) Species reactivity (tested):Human.
纯化方法 Protein A affinity Chromatography
纯度 > 95 % pure by SDS-PAGE
背景 Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75 % of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.Synonyms: Human Immunoglobulin G
分子量 150 kDa
研究领域 Immunology, Secondary Antibodies
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
限制 仅限研究用
浓度 1.0 mg/mL
缓冲液 PBS, pH ~7.4, 15 mM Sodium Azide
储存液 Sodium azide
注意事项 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
厂商提供的图像
Western Blotting (WB) image for Mouse anti-Human IgG (Fc Region) antibody (ABIN614786) Mouse anti-Human IgG (Fc Region) antibody
背景 Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." in: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." in: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." in: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).

Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).