CD180 抗体
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- 抗原 See all CD180 抗体
- CD180 (CD180 Molecule (CD180))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD180 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- 特异性
- This antibody detects CD180.
- 交叉反应 （详细）
- Species reactivity (tested):Human
- 纯化方法
- Protein-A affinity chromatography
- 纯度
- > 95 % pure by SDS-PAGE
- 免疫原
- Human tonsillar B cells
- 克隆位点
- G28-8
- 亚型
- IgG1
- Top Product
- Discover our top product CD180 Primary Antibody
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anti-CD180 Molecule (CD180) antibody
CD180 适用: 人 FACS, IP, Func 宿主: 小鼠 Monoclonal G28-8 unconjugated
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal G28-8 unconjugated
anti-CD180 Molecule (CD180) (Internal Region) antibodyCD180 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) antibody (APC)CD180 适用: 人 FACS 宿主: 小鼠 Monoclonal G28-8 APC
anti-CD180 Molecule (CD180) antibody (PE)CD180 适用: 人 FACS 宿主: 小鼠 Monoclonal G28-8 PE
anti-CD180 Molecule (CD180) antibodyCD180 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) (C-Term) antibodyCD180 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-CD180 Molecule (CD180) (N-Term) antibodyCD180 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS with 15 mM sodium azide, approx. pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- CD180 (CD180 Molecule (CD180))
- 别名
- CD180 / RP105 (CD180 产品)
- 别名
- Ly78 antibody, CD180 antibody, LY64 antibody, RP105 antibody, F630107B15 antibody, CD180 molecule antibody, CD180 antigen antibody, Cd180 antibody, CD180 antibody
- 背景
- CD180, also known as RP105 (or Bgp95, LY64) is a type I membrane glycoprotein of Toll-like receptor (TLR) family. Its cytoplasmic tail is short and unlike the TLRs, it lacks the TIR domain. CD180 expression is dependent on the coexpression of its helper molecule, MD-1 , and mirrors that of TLR4 on antigen-presenting cells. CD180 regulates recognition of LPS and signaling in B cells, via interacting directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligands. Ligation of CD180 by monoclonal antibodies leads to B cell activation, upregulation of CD80/CD86, and increase in cell size.Synonyms: LY64, Lymphocyte antigen 64, Radioprotective 105 kDa protein
- 基因ID
- 4064
- NCBI登录号
- NP_005573
- UniProt
- Q99467
- 途径
- Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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