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ELAVL1 抗体

ELAVL1 适用: 人, 小鼠, 大鼠, 斑马鱼 WB, IHC, ELISA, IP, ChIP 宿主: 小鼠 Monoclonal 19F12 unconjugated
产品编号 ABIN577055
发货至: 中国
  • 抗原 See all ELAVL1 抗体
    ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
    适用
    • 55
    • 28
    • 26
    • 15
    • 15
    • 14
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 斑马鱼
    宿主
    • 42
    • 13
    小鼠
    克隆类型
    • 34
    • 21
    单克隆
    标记
    • 23
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ELAVL1 antibody is un-conjugated
    应用范围
    • 29
    • 21
    • 16
    • 16
    • 10
    • 7
    • 6
    • 5
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP)
    特异性
    Greater than 95%
    纯化方法
    Purified IgG
    纯度
    > 98 %
    免疫原
    Synthetic Peptide
    克隆位点
    19F12
    亚型
    IgG1
    Top Product
    Discover our top product ELAVL1 Primary Antibody
  • 应用备注
    Works on IHC at 1/2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1mg/ml
    缓冲液
    PBS /glycerol
    储存条件
    -20 °C
  • Ni, Zhou, Song, Chen, Wang, Du, Zhang: "ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection." in: Communications biology, Vol. 4, Issue 1, pp. 251, (2021) (PubMed).

    Li, Lu, Dai, Torregroza, Hla, Evans: "Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1." in: Blood, Vol. 123, Issue 9, pp. 1384-92, (2014) (PubMed).

    Chang, Lu, Li, Hsieh, Xiong, Ghosh, Evans, Elemento, Hla: "Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis." in: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4908-21, (2013) (PubMed).

    García-Domínguez, Morello, Cisneros, Kontoyiannis, Frade: "Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis." in: Molecular biology of the cell, Vol. 22, Issue 8, pp. 1227-39, (2011) (PubMed).

  • 抗原
    ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
    别名
    HuR (ELAVL1 产品)
    别名
    ELAV1 antibody, HUR antibody, Hua antibody, MelG antibody, HuR antibody, 2410055N02Rik antibody, W91709 antibody, elra antibody, fa25f08 antibody, fb59a02 antibody, fc60g02 antibody, hua antibody, wu:fa25f08 antibody, wu:fb59a02 antibody, wu:fc60g02 antibody, zHuA antibody, Elavl1 antibody, Xel-1 antibody, elav1 antibody, elrA antibody, hur antibody, melg antibody, p36 antibody, ElrA antibody, elavl1 antibody, elavl1-a antibody, elavl1-b antibody, ELAV like RNA binding protein 1 antibody, ELAV-like protein 1 antibody, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R) antibody, ELAV like RNA binding protein 1a antibody, ELAV like RNA binding protein 1 L homeolog antibody, ELAV like RNA binding protein 1 S homeolog antibody, ELAVL1 antibody, Elavl1 antibody, elav1 antibody, elavl1a antibody, elavl1.L antibody, elavl1.S antibody
    背景
    HuR (also called Elavl-1 or HuA) is a protein that binds to specific AU-rich elements in a mRNA and thereby upregulates its expression. The protein contains three RRM type RNA binding domains. The first and second RNA binding domains interact with the AU-rich element. HuR is a member of a family of proteins called the elav-like proteins. The other members, HuD, HuC, and HEL-N1 are predominantly expressed in neurons. Monoclonal 19F12 was designed by CLONEGENE and was generated against a unique HuR peptide and does not react with HuD, HuC, or Hel-N1.
    途径
    AMPK Signaling
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