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GABRA1 抗体 (Middle Region)

GABRA1 适用: 大鼠, 人, 小鼠, Cow, 犬, 兔, 马, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501360
发货至: 中国
  • 抗原 See all GABRA1 抗体
    GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
    抗原表位
    • 20
    • 19
    • 19
    • 19
    • 15
    • 15
    • 15
    • 14
    • 11
    • 11
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 130
    • 106
    • 85
    • 14
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠, 人, 小鼠, Cow, 犬, 兔, 马, 豚鼠, 斑马鱼
    宿主
    • 99
    • 73
    • 2
    克隆类型
    • 99
    • 75
    多克隆
    标记
    • 54
    • 12
    • 11
    • 11
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    This GABRA1 antibody is un-conjugated
    应用范围
    • 164
    • 79
    • 73
    • 67
    • 31
    • 28
    • 26
    • 26
    • 17
    • 12
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    YDLLGQTVDS GIVQSSTGEY VVMTTHFHLK RKIGYFVIQT YLPCIMTVIL
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against GABRA1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human GABRA1
    Top Product
    Discover our top product GABRA1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 456 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
    别名
    GABRA1 (GABRA1 产品)
    别名
    ECA4 antibody, EJM antibody, EJM5 antibody, zgc:153566 antibody, Gabra-1 antibody, gamma-aminobutyric acid type A receptor alpha1 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 1 antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 antibody, gamma-aminobutyric acid receptor subunit alpha-1 antibody, GABRA1 antibody, Gabra1 antibody, gabra1 antibody, LOC100653509 antibody
    背景
    GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene.
    Alias Symbols: ECA4, EJM, EJM5
    Protein Interaction Partner: UBQLN1, PRKCG, PRKCD, PPP3CA,
    Protein Size: 456
    分子量
    52 kDa
    基因ID
    2554
    NCBI登录号
    NM_000806, NP_000797
    UniProt
    P14867
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