KCNA1 抗体 (Middle Region)
(2 references)-
- 抗原 See all KCNA1 抗体
- KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, Pig, 犬, 马, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCNA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ISIVIFCLET LPELKDDKDF TGTVHRIDNT TVIYNSNIFT DPFFIVETLC
- 预测反应
- Dog: 100%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against KCNA1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human KCNA1
- Top Product
- Discover our top product KCNA1 Primary Antibody
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anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) (AA 7-150) antibody
KCNA1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) antibodyKCNA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) (AA 410-495) antibodyKCNA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) (AA 1-495) antibodyKCNA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) (1st Extracellular Loop), (AA 193-206) antibodyKCNA1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, LCI, FACS 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) (1st Extracellular Loop), (AA 193-206) antibody (Atto 594)KCNA1 适用: 人, 小鼠, 大鼠 IHC, IF, ICC, LCI 宿主: 兔 Polyclonal Atto 594
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) antibodyKCNA1 适用: 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) antibodyKCNA1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1) (AA 179-228) antibodyKCNA1 适用: 人, Pig, 犬, 马, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 495 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation." in: Basic research in cardiology, Vol. 110, Issue 5, pp. 505, (2015) (PubMed).
: "Clinical spectrum of voltage-gated potassium channel autoimmunity." in: Neurology, Vol. 70, Issue 20, pp. 1883-90, (2008) (PubMed).
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: "Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation." in: Basic research in cardiology, Vol. 110, Issue 5, pp. 505, (2015) (PubMed).
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- 抗原
- KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))
- 别名
- KCNA1 (KCNA1 产品)
- 别名
- AEMK antibody, EA1 antibody, HBK1 antibody, HUK1 antibody, KV1.1 antibody, MBK1 antibody, MK1 antibody, RBK1 antibody, KCNA1 antibody, AI840627 antibody, Kca1-1 antibody, Kv1.1 antibody, Mk-1 antibody, Shak antibody, mceph antibody, Kcna antibody, Kcpvd antibody, potassium voltage-gated channel subfamily A member 1 antibody, potassium voltage-gated channel, shaker-related subfamily, member 1 antibody, fragile site, aphidicolin type, common, fra(12)(q24) antibody, KCNA1 antibody, Kcna1 antibody, FRA12E antibody
- 背景
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KCNA1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). Sequence Note: This RefSeq record was created largely from genomic sequence because transcripts were not available for the entire length of the gene. This transcript is supported by sequences from mouse. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MGC126782, MGC138385, MK1, RBK1
Protein Interaction Partner: KCNRG, KCNE4, DLG4, DLG1, KCNA4, KCNA3, KCNA2, RTN4, CNTNAP1,
Protein Size: 495 - 分子量
- 56 kDa
- 基因ID
- 3736
- NCBI登录号
- NM_000217, NP_000208
- UniProt
- Q09470
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