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DHPS 抗体

DHPS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499058
发货至: 中国
  • 抗原 See all DHPS 抗体
    DHPS (Deoxyhypusine Synthase (DHPS))
    适用
    • 58
    • 15
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 57
    • 2
    克隆类型
    • 59
    多克隆
    标记
    • 23
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DHPS antibody is un-conjugated
    应用范围
    • 47
    • 25
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of DHS protein. (region surrounding Leu87)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product DHPS Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DHPS (Deoxyhypusine Synthase (DHPS))
    Abstract
    DHPS 产品
    别名
    MGC76269 antibody, zgc:56018 antibody, zgc:77325 antibody, wu:fb52g04 antibody, wu:fj48f12 antibody, zgc:111900 antibody, MGC82178 antibody, DDBDRAFT_0186679 antibody, DDBDRAFT_0266388 antibody, DDB_0186679 antibody, DDB_0266388 antibody, DHS antibody, DS antibody, MIG13 antibody, Dhs antibody, DYS antibody, EDA22 antibody, K18J17.7 antibody, K18J17_7 antibody, deoxyhypusine synthase antibody, embryo sac development arrest 22 antibody, deoxyhypusine synthase antibody, deoxyhypusine synthase S homeolog antibody, Deoxyhypusine synthase antibody, DHPS antibody, dhps antibody, dhps.S antibody, SHELL_RS05250 antibody, PF14_0125 antibody, CNJ02480 antibody, Tb10.70.4900 antibody, Tb927.1.870 antibody, MMAH_RS09430 antibody, TAGG_RS03310 antibody, TAGG_RS05175 antibody, Mesil_2448 antibody, Trad_0088 antibody, Igag_1842 antibody, Desac_0724 antibody, MZHIL_RS05480 antibody, MZHIL_RS05835 antibody, MZHIL_RS06250 antibody, Dhps antibody, DHS antibody
    背景
    Deoxyhypusine synthase (DHS) is crucial for the posttranslational formation of hypusine, a modification of a specific lysine residue in eukaryotic initiation factor 5A (eIF-5A). Hypusine is formed by posttranslational modifications involving two enzymatic steps catalyzed by DHS and deoxyhypusine hydroxylase (DOHH). eIF-5A is essential for eukaryotic cell proliferation. DHS, which belongs to the deoxyhypusine synthase family of proteins, is important for the first step in the hypusine biosynthesis pathway. It acts as a catalyst for the NAD-dependent oxidative cleavage of spermidine and the ensuing transfer of the butylamine moiety of spermidine to the eIF-5A protein, to create the intermediate deoxyhypusine residue.
    分子量
    approx. 45 kDa
    基因ID
    1725
    NCBI登录号
    NP_001921
    UniProt
    P49366
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