电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

ARR3 抗体

ARR3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498372
发货至: 中国
  • 抗原 See all ARR3 抗体
    ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))
    适用
    • 19
    • 11
    • 2
    • 1
    宿主
    • 15
    • 3
    • 1
    克隆类型
    • 18
    • 1
    多克隆
    标记
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARR3 antibody is un-conjugated
    应用范围
    • 11
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Arrestin-C protein. (region surrounding Glu374)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product ARR3 Primary Antibody
  • 应用备注
    Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ARR3 (Arrestin 3, Retinal (X-Arrestin) (ARR3))
    别名
    Arrestin C / ARR3 (ARR3 产品)
    别名
    ARRX antibody, arr3 antibody, si:bz46j2.6 antibody, zgc:73331 antibody, Arr4 antibody, Car antibody, Carfl antibody, Carr antibody, arr3l antibody, c-arrestin antibody, zgc:92697 antibody, arrestin 3 antibody, arrestin 3, retinal (X-arrestin) L homeolog antibody, arrestin 3, retinal (X-arrestin) antibody, arrestin 3b, retinal (X-arrestin) antibody, arrestin 3, retinal antibody, arrestin 3a, retinal (X-arrestin) antibody, ARR3 antibody, arr3.L antibody, arr3 antibody, arr3b antibody, Arr3 antibody, arr3a antibody
    背景
    Members of Arrestin/beta-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Arrestin-C, also known as retinal cone Arrestin-3, X-Arrestin or cArr, is a member of the Arrestin family of proteins. It is predominantly found in the retina and pineal gland and localizes to the inner and outer segments of red-, green- and blue-cone photoreceptors and the inner plexiform regions. Two Arrestin-C isoforms exist due to alternative splicing. Isoform 1 is the mature full length protein and isoform 2 is truncated, ending with an arginine for amino acid residue 359. Arrestin-C expression is stimulated by retinoic acid. It may play a role in retina-specific signal transduction and bind to photoactivated-phosphorylated red/green opsins. In addition, Arrestin-C forms homodimers and oligomers with beta-Arrestins and may regulate beta-Arrestin mediated signaling.Synonyms: ARRX, C-ARR, C-Arrestin, CAR, Cone arrestin, Retinal cone arrestin-3, X-arrestin
    分子量
    approx. 40 kDa
    基因ID
    407
    NCBI登录号
    NP_004303
    UniProt
    P36575
    途径
    Phototransduction, Thromboxane A2 Receptor Signaling
客服