(1 reference)-
- 抗原
- MAPK1/2
-
抗原表位
- C-Term
- 适用
- 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- 非结合性
-
应用范围
- Western Blotting (WB)
- 特异性
- Specific for the ~42k - 44k ERK/MAPK protein. Immunolabeling is blocked by the peptide used as antigen.
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- mouse
- 纯化方法
- Antigen Affinity Purified from Pooled Serum
- 免疫原
- Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH
-
anti-MAPK1/2 (pThr202), (pTyr204) antibody
适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
- 100 μL in 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
- 储存条件
- -20 °C
-
-
: "Initial analysis of peripheral lymphocytic extracellular signal related kinase activation in autism." in: Journal of psychiatric research, Vol. 84, pp. 153-160, (2017) (PubMed).
-
: "Initial analysis of peripheral lymphocytic extracellular signal related kinase activation in autism." in: Journal of psychiatric research, Vol. 84, pp. 153-160, (2017) (PubMed).
-
- 抗原
- MAPK1/2
- 背景
- Extracellular-Signal Regulated Kinase/Mitogen-Activated Protein Kinase (ERK/MAPK) is an integral component of cellular signaling during mitogenesis and differentiation of mitotic cells and also is thought to play a key role in learning and memory (Adams and Sweatt, 2002, Ahn, 1993, Tanoue and Nishida, 2003, Johnson and Lapadat, 2002). The activity of this kinase is regulated by dual phosphorylation at Thr202 and Tyr204 (Ahn, 1993). Anti-ERK/MAPK Western blot of rat hippocampal homogenate showing specific immunolabeling of ~42-44k ERK/MAPK protein.
- 分子量
- 42/44 kDa
- 基因ID
- 116590
- UniProt
- P63086
-
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