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CD53 抗体 (PE)

CD53 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-53 PE
产品编号 ABIN303518
发货至: 中国
  • 抗原 See all CD53 抗体
    CD53
    适用
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    宿主
    • 43
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    小鼠
    克隆类型
    • 42
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    单克隆
    标记
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    This CD53 antibody is conjugated to PE
    应用范围
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    • 29
    • 25
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    Flow Cytometry (FACS)
    纯化方法
    Size-exclusion chromatography
    免疫原
    Leukocytes of pacient suffering from a LGL-type leukemia
    克隆位点
    MEM-53
    亚型
    IgG1
    Top Product
    Discover our top product CD53 Primary Antibody
  • 应用备注
    Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 10^6 cells in a suspension.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Dilute only prior to immediate use
    储存条件
    4 °C
    储存方法
    Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
  • 抗原
    CD53
    别名
    CD53 (CD53 产品)
    别名
    AI323659 antibody, Ox-44 antibody, Tspan25 antibody, MOX44 antibody, TSPAN25 antibody, OX44 antibody, CD53 antigen antibody, CD53 molecule antibody, Cd53 molecule antibody, Cd53 antibody, CD53 antibody
    背景
    CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.Synonyms: Cell surface glycoprotein CD53, Leukocyte surface antigen CD53, MOX44, TSPAN25, Tetraspanin-25
    基因ID
    963
    NCBI登录号
    NP_000551
    UniProt
    P19397
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