ARAP1 抗体 (AA 1190-1450)
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- 抗原 See all ARAP1 抗体
- ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))
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抗原表位
- AA 1190-1450
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ARAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 特异性
- The antibody ARAP1-2 reacts with C-terminal part of ARAP1 (intracellular epitope), a 160 kDa adaptor protein.
- 交叉反应 (详细)
- Human
- 纯化方法
- Purified by protein-A affinity chromatography.
- 纯度
- > 95 % (by SDS-PAGE)
- 免疫原
- His6-tagged protein corresponding to amino acids 1190-1450 of human ARAP1
- 克隆位点
- ARAP1-2
- 亚型
- IgG1
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- 应用备注
- Western blotting: Recommended dilution: 2 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 3, pp. 423-36, (2008) (PubMed).
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Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 3, pp. 423-36, (2008) (PubMed).
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- 抗原
- ARAP1 (ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))
- 别名
- ARAP1 (ARAP1 产品)
- 别名
- CENTD2 antibody, ARAP1 antibody, Ci-ArfGAP-8 antibody, 2410002L19Rik antibody, Centd2 antibody, mKIAA0782 antibody, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 antibody, centaurin, delta 2 antibody, ARAP1 antibody, centd2 antibody, Arap1 antibody
- 背景
- ArfGAP with RhoGAP domain, ankyrin repeat and PH d,ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.,CED2, CENTD2
- 基因ID
- 116985
- UniProt
- Q96P48
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