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Chemokine (C-C Motif) Ligand 8 (CCL8) (Middle Region) 抗体

ABIN2792194 产品详细信息, 供应商: Log in to see
抗原
  • HC14
  • MCP-2
  • MCP2
  • SCYA10
  • SCYA8
  • 1810063B20Rik
  • AB023418
  • Mcp2
  • Scya8
  • chemokine (C-C motif) ligand 8
  • monocyte chemoattractant protein-2 precursor
  • CCL8
  • Ccl8
  • MCP-2
抗原表位
Middle Region
15
6
6
5
2
1
1
1
适用

91
51
3
2
1
宿主

72
39
15
1
克隆类型
多克隆
标记
非结合性
15
7
6
4
4
3
3
3
3
3
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
应用范围
Western Blotting (WB)
101
57
15
14
8
7
4
4
4
3
2
1
1
Supplier
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免疫原 The immunogen is a synthetic peptide directed towards the middle region of human CCL8
序列 SYTRITNIQC PKEAVIFKTK RGKEVCADPK ERWVRDSMKH LDQIFQNLKP
预测反应 Human: 100%
产品特性 This is a rabbit polyclonal antibody against CCL8. It was validated on Western Blot using a cell lysate as a positive control.
纯化方法 Affinity Purified
别名 CCL8 (CCL8 Antibody 摘要)
背景 CCL8 gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HC14, MCP-2, MCP2, SCYA10, SCYA8
Protein Interaction Partner: ACKR2, ACKR4, CCR5, CCR3, CCR2, CCR1, MMP3, VCAN, ACKR1,
Protein Size: 99
分子量 9 kDa
基因ID 6355
NCBI登录号 NM_005623, NP_005614
UniProt P80075
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 99 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (Middle Region) 抗体 (ABIN2792194) anti-Chemokine (C-C Motif) Ligand 8 (CCL8) (Middle Region) antibody
背景 Hori, Naishiro, Sohma, Suzuki, Hatakeyama, Yamamoto, Sonoda, Mizue, Imai, Tsutsumi, Kokai: "CCL8 is a potential molecular candidate for the diagnosis of graft-versus-host disease." in: Blood, Vol. 111, Issue 8, pp. 4403-12, 2008 (PubMed).