Osteoprotegerin 抗体 (N-Term)
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- 抗原 See all Osteoprotegerin (TNFRSF11B) 抗体
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, 兔, 犬, Pig, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Osteoprotegerin antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- LDISIKWTTQ ETFPPKYLHY DEETSHQLLC DKCPPGTYLK QHCTAKWKTV
- 预测反应
- Dog: 78%, Horse: 78%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 78%, Rat: 78%
- 产品特性
- This is a rabbit polyclonal antibody against TNFRSF11B. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF11B
- Top Product
- Discover our top product TNFRSF11B Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 401 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
- 别名
- TNFRSF11B (TNFRSF11B 产品)
- 别名
- CD254 antibody, ODF antibody, OPGL antibody, OPTB2 antibody, RANKL antibody, TRANCE antibody, hRANKL2 antibody, sOdf antibody, OCIF antibody, OPG antibody, TR1 antibody, Opg antibody, ocif antibody, opg antibody, tr1 antibody, TNF superfamily member 11 antibody, TNF receptor superfamily member 11b antibody, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) antibody, TNF receptor superfamily member 11B antibody, tumor necrosis factor receptor superfamily member 11b S homeolog antibody, tumor necrosis factor receptor superfamily, member 11b antibody, TNFSF11 antibody, TNFRSF11B antibody, Tnfrsf11b antibody, tnfrsf11b.S antibody
- 物质类
- Chemical
- 背景
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TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
Alias Symbols: OPG, TR1, OCIF
Protein Interaction Partner: TNFSF13, TNFSF10, TNFSF11, VWF, VTN, THBS1, FN1,
Protein Size: 401 - 分子量
- 46 kDa
- 基因ID
- 4982
- NCBI登录号
- NM_002546, NP_002537
- UniProt
- O00300
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