ANTXR1 抗体 (Middle Region)
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- 抗原 See all ANTXR1 抗体
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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抗原表位
- Middle Region
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适用
- 人, 小鼠, 大鼠, 犬, 兔, Cow, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANTXR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- VRWGEKGSTE EGAKLEKAKN ARVKMPEQEY EFPEPRNLNN NMRRPSSPRK
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against ANTXR1. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ANTXR1
- Top Product
- Discover our top product ANTXR1 Primary Antibody
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anti-anthrax Toxin Receptor 1 (ANTXR1) (Tyr382) antibody
ANTXR1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (pTyr382) antibodyANTXR1 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (C-Term) antibodyVerified ANTXR1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Internal Region) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (Internal Region) antibodyANTXR1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 481-497) antibodyANTXR1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 200C1339(SB20) unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 315-564) antibodyANTXR1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) antibodyANTXR1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-anthrax Toxin Receptor 1 (ANTXR1) (AA 481-497) antibodyANTXR1 适用: 人, 犬, 兔, 猴 WB 宿主: 小鼠 Monoclonal 200C1339(SB20) unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 564 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
- 别名
- ANTXR1 (ANTXR1 产品)
- 别名
- ANTXR1 antibody, ATR antibody, TEM8 antibody, 2310008J16Rik antibody, 2810405N18Rik antibody, Antrx1 antibody, Tem8 antibody, anthrax toxin receptor 1 antibody, ANTXR1 antibody, Antxr1 antibody
- 背景
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ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. ANTXR1 has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.
Alias Symbols: ATR, FLJ10601, FLJ11298, FLJ21776, TEM8
Protein Interaction Partner: UBC, ELAVL1, Mad2l1, HDAC2, LRP6, BCL2L1,
Protein Size: 564 - 分子量
- 60 kDa
- 基因ID
- 84168
- NCBI登录号
- NM_032208, NP_115584
- UniProt
- Q9H6X2
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