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Myoferlin 抗体 (C-Term)

MYOF 适用: 人, 小鼠, Cow, 兔, 大鼠, 斑马鱼, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2782797
发货至: 中国
  • 抗原 See all Myoferlin (MYOF) 抗体
    Myoferlin (MYOF)
    抗原表位
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 小鼠, Cow, 兔, 大鼠, 斑马鱼, 犬, 豚鼠, 马
    宿主
    • 7
    • 4
    克隆类型
    • 8
    • 3
    多克隆
    标记
    • 11
    This Myoferlin antibody is un-conjugated
    应用范围
    • 11
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    QTEFRIPPRL IIQIWDNDKF SLDDYLGFLE LDLRHTIIPA KSPEKCRLDM
    预测反应
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%
    产品特性
    This is a rabbit polyclonal antibody against FER1L3. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human FER1L3
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 2061 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Myoferlin (MYOF)
    别名
    FER1L3 (MYOF 产品)
    别名
    FER1L3 antibody, 2310004N10Rik antibody, 2310051D19Rik antibody, E030042N20Rik antibody, Fer1l3 antibody, RGD1564216 antibody, zgc:63504 antibody, fer1l3 antibody, myoferlin antibody, MYOF antibody, Myof antibody, myof antibody, LOC100380767 antibody
    背景
    Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. FER1L3 is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length natures have not been determined.
    Alias Symbols: FLJ36571, FLJ90777, MYOF, FER1L3
    Protein Interaction Partner: UBC, SUMO2, SUMO3, RPA3, RPA2, RPA1, MATR3, ILF2, ATP6V1B1, CDK2, Kdr, Dnm2, ISG15, SUMO1,
    Protein Size: 2061
    分子量
    235 kDa
    基因ID
    26509
    NCBI登录号
    NM_013451, NP_038479
    UniProt
    Q9NZM1
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