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MED17 抗体 (Mediator Complex Subunit 17) (N-Term)

Details for Product anti-MED17 Antibody No. ABIN2778320, 供应商: Log in to see
抗原
  • crsp6
  • CRSP6
  • CRSP77
  • DRIP80
  • TRAP80
  • 77kDa
  • C330002H14Rik
  • Crsp6
  • Trap80
  • mediator of RNA polymerase II transcription subunit 17
  • Mediator of RNA polymerase II transcription subunit 17
  • mediator complex subunit 17
  • AOR_1_2446154
  • VDBG_01663
  • med17
  • MED17
  • Med17
Alternatives
anti-牛 MED17 抗体 for Western Blotting
抗原表位
N-Term
15
10
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8
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3
2
2
2
2
1
1
1
1
适用
牛, 犬, 豚鼠, 马, 人, 小鼠, 兔, 大鼠
79
29
21
2
1
1
1
1
1
1
1
1
宿主

60
19
克隆类型
多克隆
标记
This MED17 antibody is un-conjugated
4
4
4
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3
3
1
1
1
1
1
1
1
1
1
1
1
应用范围
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry (IHC), Western Blotting (WB)
61
36
13
12
12
9
8
3
1
Supplier
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免疫原 The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6
Blocking Peptide Blocking peptide for this product available: ABIN975330
序列 AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG
预测反应 Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
产品特性 This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.
纯化方法 Affinity Purified
别名 CRSP6 (MED17 Antibody 摘要)
背景 The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
Protein Size: 651
分子量 73 kDa
基因ID 9440
NCBI登录号 NM_004268, NP_004259
UniProt Q9NVC6
途径 Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
应用备注 Optimal working dilutions should be determined experimentally by the investigator.
说明

Antigen size: 651 AA

限制 仅限研究用
状态 Liquid
浓度 Lot specific
缓冲液 Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
厂商提供的图像
Western Blotting (WB) image for anti-MED17 抗体 (Mediator Complex Subunit 17) (N-Term) (ABIN2778320) WB Suggested Anti-CRSP6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-MED17 抗体 (Mediator Complex Subunit 17) (N-Term) (ABIN2778320) anti-Mediator Complex Subunit 17 (MED17) (N-Term) antibody (Image 2)
Chromatin Immunoprecipitation (ChIP) image for anti-MED17 抗体 (Mediator Complex Subunit 17) (N-Term) (ABIN2778320) Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-MED17 抗体 (Mediator Complex Subunit 17) (N-Term) (ABIN2778320) Rabbit Anti-MED17 Antibody ,Paraffin Embedded Tissue: Human neural cell
Cellul...
背景 Wang, Sharma, Ren, Fondell: "A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression." in: The Journal of biological chemistry, Vol. 277, Issue 45, pp. 42852-8, 2002 (PubMed).