ATP7A 抗体 (AA 42-61) (PE)
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- 抗原 See all ATP7A 抗体
- ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
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抗原表位
- AA 42-61
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ATP7A antibody is conjugated to PE
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Detects ~180 kDa in rat brain membrane preparations.
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Protein G Purified
- 免疫原
- Synthetic peptide amino acids 42-61 (cytoplasmic C-terminus) of human Copper- transporting ATPase1
- 克隆位点
- S60-4
- 亚型
- IgG2b
- Top Product
- Discover our top product ATP7A Primary Antibody
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anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (HRP)
ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 HRP
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (FITC)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 FITC
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Biotin)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Biotin
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (APC)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 APC
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (PerCP)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 PerCP
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Atto 488)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Atto 488
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Atto 594)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Atto 594
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Atto 390)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Atto 390
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 242-285) antibodyATP7A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) antibodyATP7A 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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- WB (1:500)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- 说明
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1 μg/ml of ABIN2485196 was sufficient for detection of Copper-transporting ATPase1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat IgG:HRP as the secondary antibody.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Conjugated antibodies should be stored at 4°C
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- 抗原
- ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
- 别名
- ATP7A (ATP7A 产品)
- 别名
- ATP7A antibody, cal antibody, wu:fc43e01 antibody, zgc:153422 antibody, zgc:158633 antibody, DDBDRAFT_0218568 antibody, DDBDRAFT_0235190 antibody, DDB_0218568 antibody, DDB_0235190 antibody, atpase antibody, Atp7a antibody, kal antibody, atp7a antibody, DSMAX antibody, MK antibody, MNK antibody, SMAX3 antibody, Blo antibody, DXHXS1608e antibody, I14 antibody, Mo antibody, blotchy antibody, br antibody, brindled antibody, mottled antibody, Mnk antibody, ATPase copper transporting alpha antibody, ATPase, Cu++ transporting, alpha polypeptide antibody, P-type ATPase antibody, ATP synthase subunit a antibody, copper-transporting ATPase 1 antibody, ATP7A antibody, atp7a antibody, LOC100049514 antibody, Atp7a antibody, LOC412379 antibody
- 背景
- The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7A (also known as Copper-transporting ATPase 1) functions as a transmembrane copper-trans locating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney. Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo. Although ATP7A is not detectable in most normal tissues, it is expressed in a considerable fraction of many common tumor types. Increased expression of ATP7A renders cells resistant to cisplatin and carboplatin. Mutations in the ATP7A gene result in Menkes disease, which is fatal in early childhood. Mutations in the ATP7B gene lead to the autosomal recessive disorder, Wilson disease, characterized by neurological symptoms and hepatic damage.
- 基因ID
- 538
- NCBI登录号
- NP_000043
- UniProt
- Q04656
- 途径
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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