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CMKLR1 抗体 (AA 151-250)

CMKLR1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IF (cc), IF (p), FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1715118
发货至: 中国
  • 抗原 See all CMKLR1 抗体
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    抗原表位
    • 15
    • 15
    • 14
    • 11
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-250
    适用
    • 68
    • 41
    • 23
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Pig
    宿主
    • 70
    • 3
    • 2
    克隆类型
    • 68
    • 6
    • 1
    多克隆
    标记
    • 31
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CMKLR1 antibody is un-conjugated
    应用范围
    • 61
    • 28
    • 25
    • 25
    • 19
    • 12
    • 9
    • 9
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, Pig, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from mouse CMKLR1
    亚型
    IgG
    Top Product
    Discover our top product CMKLR1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Qu, Zhang, Yao, Song, Nikolic-Paterson, Li: "Resolvins E1 and D1 inhibit interstitial fibrosis in the obstructed kidney via inhibition of local fibroblast proliferation." in: The Journal of pathology, Vol. 228, Issue 4, pp. 506-19, (2014) (PubMed).

    Peng, Yu, Liu, Li, He, Cheng, Ye: "The Chemerin Receptor CMKLR1 is a Functional Receptor for Amyloid-? Peptide." in: Journal of Alzheimer's disease : JAD, (2014) (PubMed).

  • 抗原
    CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))
    别名
    CMKLR1 (CMKLR1 产品)
    别名
    CHEMERINR antibody, ChemR23 antibody, DEZ antibody, RVER1 antibody, Gpcr27 antibody, mcmklr1 antibody, si:ch211-240b21.3 antibody, CMLKR1 antibody, Cmklr-1 antibody, GPCR antibody, chemerin chemokine-like receptor 1 antibody, chemokine-like receptor 1 antibody, CMKLR1 antibody, Cmklr1 antibody, cmklr1 antibody
    背景

    Synonyms: DEZ, Gpcr27, ChemR23, mcmklr1, Chemokine-like receptor 1, G-protein coupled receptor DEZ, Cmklr1

    Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B (By similarity). Positively regulates adipogenesis and adipocyte metabolism.

    基因ID
    14747
    UniProt
    P97468
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