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GAMT 抗体 (AA 101-200)

GAMT 适用: 人 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1713803
发货至: 中国
  • 抗原 See all GAMT 抗体
    GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
    抗原表位
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    适用
    • 24
    • 21
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 38
    • 2
    克隆类型
    • 39
    • 1
    多克隆
    标记
    • 21
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GAMT antibody is un-conjugated
    应用范围
    • 22
    • 10
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GAMT
    亚型
    IgG
    Top Product
    Discover our top product GAMT Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    GAMT (Guanidinoacetate N-Methyltransferase (GAMT))
    别名
    GAMT (GAMT 产品)
    别名
    gamt antibody, zgc:123136 antibody, CCDS2 antibody, PIG2 antibody, TP53I2 antibody, AA571402 antibody, Spintz1 antibody, MGC75698 antibody, GAMT antibody, GMT antibody, guanidinoacetate N-methyltransferase L homeolog antibody, guanidinoacetate N-methyltransferase S homeolog antibody, guanidinoacetate N-methyltransferase antibody, guanidinoacetate methyltransferase antibody, gamt.L antibody, gamt.S antibody, gamt antibody, GAMT antibody, Gamt antibody
    背景

    Synonyms: PIG2, CCDS2, TP53I2, HEL-S-20, Guanidinoacetate N-methyltransferase, GAMT

    Background: In the creatine biosynthesis pathway, glycine is converted to guanidinoacetate by amidinotransferase, and guanidinoacetate is then converted to creatine by Guanidinoacetate N-methyltransferase (GAMT). GAMT, a methyltransferase, uses S-adenosylmethionine as the methyl donor for this reaction. Methyltransferases are a type of transferase enzyme which transfers a methyl group to nucleic bases in DNA or amino acids in protein. Encoding a 236 amino acid protein, the human GAMT gene maps to chromosome 19p13.3. Defects in the GAMT gene leads to GAMT deficiency, which is associated with guanidinoacetate accumulation and decreased levels of creatine excretion in brain. Such biochemical changes are thought to lead to various neurological syndromes and muscular hypotonia.

    基因ID
    2593
    UniProt
    Q14353
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