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SLC1A6 抗体 (PE)

SLC1A6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal PE
产品编号 ABIN1712764
发货至: 中国
  • 抗原 See all SLC1A6 抗体
    SLC1A6 (Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6))
    适用
    • 44
    • 17
    • 10
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 43
    • 3
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 14
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC1A6 antibody is conjugated to PE
    应用范围
    • 30
    • 15
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EAAT4
    亚型
    IgG
    Top Product
    Discover our top product SLC1A6 Primary Antibody
  • 应用备注
    FCM(1:20-100)
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SLC1A6 (Solute Carrier Family 1 (High Affinity Aspartate/glutamate Transporter), Member 6 (SLC1A6))
    别名
    Eaat4 (SLC1A6 产品)
    别名
    SLC1A6 antibody, zgc:171923 antibody, EAAT4 antibody, solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 antibody, solute carrier family 1 member 6 antibody, excitatory amino acid transporter 4-like antibody, SLC1A6 antibody, slc1a6 antibody, LOC100224299 antibody, Slc1a6 antibody
    背景

    Synonyms: Excitatory amino acid transporter 4, High affinity neuronal glutamate transporter, MGC33092, MGC43671, Sodium dependent glutamate/aspartate transporter, Solute carrier family 1 high affinity aspartate/glutamate transporter member 6, Solute carrier family 1 member 6 ,EAA4_HUMAN.

    Background: Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.

    基因ID
    6511
    UniProt
    P48664
    途径
    Dicarboxylic Acid Transport
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