电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CARD14 抗体 (C-Term)

CARD14 适用: 人 IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1449966
发货至: 中国
  • 抗原 See all CARD14 抗体
    CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
    抗原表位
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 33
    • 21
    • 4
    宿主
    • 29
    • 3
    • 1
    克隆类型
    • 31
    • 2
    多克隆
    标记
    • 15
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARD14 antibody is un-conjugated
    应用范围
    • 24
    • 14
    • 13
    • 13
    • 6
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    纯化方法
    Affinity Chromatography purified via peptide column
    免疫原
    14 amino acid synthetic peptide near the carboxy terminus of Human CARMA2
    亚型
    IgG
    Top Product
    Discover our top product CARD14 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CARD14 (Caspase Recruitment Domain Family, Member 14 (CARD14))
    别名
    CARD14 / CARMA2 (CARD14 产品)
    别名
    BIMP2 antibody, CARMA2 antibody, PRP antibody, PSORS2 antibody, PSS1 antibody, Bimp2 antibody, caspase recruitment domain family member 14 antibody, caspase recruitment domain family, member 14 antibody, CARD14 antibody, Card14 antibody
    背景
    CARMA proteins belong to the membrane-associated guan-ylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARMA1, CARMA2, and CARMA3 share high degrees of sequence and functional homology, but their tissue-specific distribution suggests that they serve distinct biological functions in different cell types. As with CARMA1, the CARD domain of CARMA2 has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kB activation. When expressed in cells, this protein activated NF-kB and induced the phosphorylation of BCL10 Alternative splicing of CARMA2 results in isoforms that possess differential effects on NF-kB activation and endoplasmic reticulum stress-induced cell death.Synonyms: CARD-containing MAGUK protein 2, Caspase recruitment domain-containing protein 14
    基因ID
    79092
    NCBI登录号
    NP_077015
You are here:
客服