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DLG1 抗体 (AA 801-904)

DLG1 适用: 人 ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387516
发货至: 中国
  • 抗原 See all DLG1 抗体
    DLG1 (Discs, Large Homolog 1 (DLG1))
    抗原表位
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 801-904
    适用
    • 27
    • 19
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 23
    • 8
    • 1
    • 1
    克隆类型
    • 25
    • 8
    多克隆
    标记
    • 22
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLG1 antibody is un-conjugated
    应用范围
    • 20
    • 11
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SAP97
    亚型
    IgG
    Top Product
    Discover our top product DLG1 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Lowe, Usowicz, Hodge: "Neuronal overexpression of Alzheimer's disease and Down's syndrome associated DYRK1A/minibrain gene alters motor decline, neurodegeneration and synaptic plasticity in Drosophila." in: Neurobiology of disease, Vol. 125, pp. 107-114, (2019) (PubMed).

  • 抗原
    DLG1 (Discs, Large Homolog 1 (DLG1))
    别名
    SAP97 (DLG1 产品)
    别名
    DLG1 antibody, Dlgh1 antibody, SAP97 antibody, B130052P05Rik antibody, E-dlg/SAP97 antibody, SAP-97 antibody, mKIAA4187 antibody, DLGH1 antibody, dJ1061C18.1.1 antibody, hdlg antibody, discs large MAGUK scaffold protein 1 antibody, discs, large homolog 1 (Drosophila) antibody, DLG1 antibody, Dlg1 antibody
    背景

    Synonyms: Discs large homolog 1, Disks large homolog 1, DLG 1, DLG1, DLG1_HUMAN, DLGH 1, DLGH1, HDLG, Presynaptic protein SAP97, SAP 97, SAP-97, SAP97, Synapse associated protein 97, Synapse-associated protein 97

    Background: The discs large (dlg) tumor suppressor gene was first identified in Drosophila through genetic analysis of germline mutations. Several mammalian homologs were subsequently identified and categorized into a protein family designated MAGUK (membrane-associated guanylate kinase homolog). The mammalian homolog of dlg, SAP 97, is also known as hdlg-1 (human) and NE-dlg (neuronal and endocrine). The rat synaptic protein SAP 90 (also designated PSD-95) also shares homology with these proteins. MAGUKs are localized at the membrane-cytoskeleton interface and contain several distinct domains which suggest a role for these proteins in intracellular signal transduction. Interaction of hdlg-1 and NE-dlg with the tumor suppresor protein APC suggest that MAGUK proteins may also play a role in regulation of growth.

    基因ID
    1739
    途径
    Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
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