L-Selectin 抗体
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北京 101111
Quick Overview for L-Selectin 抗体 (ABIN135253)
抗原
See all L-Selectin (SELL) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat Anti-Mouse CD62L-LE/AF
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特异性
- Mouse CD62L, Mr 74 kDa on lymphocytes and Mr 95 kDa on neutrophils
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产品特性
- Low Endotoxin/Azide Free Anti-Mouse CD62L antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, blocking, and cytotoxicity assays.
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内毒素水平
- Low Endotoxin
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免疫原
- C3H/eb cloned mouse B cell lymphoma 38C-13
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.4
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- L-Selectin (SELL) (Selectin L (SELL))
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别名
- CD62L
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背景
- CD62L, also known as L-selectin, is a type I transmembrane glycoprotein with lectin-like and Epidermal Growth Factor-like domains. It binds to sialylated oligosaccharide determinants on high endothelial venules (HEV) in peripheral lymph nodes. In the mouse, CD62L is expressed on most thymocytes and on peripheral leukocytes, including B and T lymphocytes, neutrophils, monocytes and eosinophils. This member of the selectin family of cell adhesion molecules appears to be required for lymphocyte homing to peripheral lymph nodes and for leukocyte extravasation at sites of inflammation. Expression of CD62L on lymphocytes and neutrophils is rapidly down-regulated upon cell activation and the level of CD62L expression, along with other markers, distinguishes naive T cells from effector/memory T cells.
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基因ID
- 20343
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UniProt
- P18337
抗原
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