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VTCN1 抗体

VTCN1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN1077428
发货至: 中国
  • 抗原 See all VTCN1 抗体
    VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
    适用
    • 78
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    人, 小鼠
    宿主
    • 70
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    • 2
    克隆类型
    • 67
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    • 1
    单克隆
    标记
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    This VTCN1 antibody is un-conjugated
    应用范围
    • 54
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    • 27
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    Western Blotting (WB), ELISA
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    Rabbit polyclonal VTCN1 antibody was raised against an 18 amino acid peptide near the center of human VTCN1.
    亚型
    IgG
    Top Product
    Discover our top product VTCN1 Primary Antibody
  • 应用备注
    VTCN1 antibody can be used for detection of VTCN1 by Western blot at 1 - 2 μg/mL.
    说明

    (IN) V-set domain containing T cell activation inhibitor 1

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    储存条件
    4 °C/-20 °C
    储存方法
    VTCN1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
    有效期
    12 months
  • 抗原
    VTCN1 (V-Set Domain Containing T Cell Activation Inhibitor 1 (VTCN1))
    别名
    VTCN1 (VTCN1 产品)
    别名
    B7h4 antibody, B7s1 antibody, B7x antibody, BC032925 antibody, B7-H4 antibody, B7H4 antibody, B7S1 antibody, B7X antibody, B7h.5 antibody, PRO1291 antibody, VCTN1 antibody, RGD1311204 antibody, V set domain containing T cell activation inhibitor 1 L homeolog antibody, V-set domain containing T cell activation inhibitor 1 antibody, V-set domain containing T-cell activation inhibitor 1 antibody, V set domain containing T cell activation inhibitor 1 antibody, vtcn1.L antibody, VTCN1 antibody, vtcn1 antibody, Vtcn1 antibody
    背景
    T cell immunity plays a critical role in host immune surveillance of tumour cell growth and metastatic spread. VTCN1, also known as B7-H4, is a member of the B7 family of immune regulatory molecules. Expressed primarily on the membrane of lymphoid cells, VTCN1 is an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of VTCN1 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumour cells suppress T cell immunity and facilitate tumour progression. VTCN1 may thus be a useful biomarker for the early detection of ovarian cancer.
    Synonyms: V-set domain containing T cell activation inhibitor 1, T cell costimulatory molecule B7x, B7-H4, B7H4, B7S1, B7X
    分子量
    31 kDa (calculated)
    基因ID
    79679
    NCBI登录号
    NP_078902
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