anti-CRTC2 (CRTC2) 抗体产品概述

Full name:
anti-CREB Regulated Transcription Coactivator 2 抗体 (CRTC2)
在www.antibodies-online.cn可供178 CREB Regulated Transcription Coactivator 2 (CRTC2) 抗体的23不同的供货商。 再加上,我们可以发CRTC2 蛋白 (5)和数多这个蛋白质的别的产品。 总共197 CRTC2产品已列进来了。
别名:
4632407F12Rik, CRTC2, mTORC2, RGD1308903, TORC-2, Torc2

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引用最多的anti-CRTC2 抗体

  1. Human Monoclonal CRTC2 Primary Antibody for ICC, FACS - ABIN969067 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)
    Show all 3 references for 969067

  2. Human Polyclonal CRTC2 Primary Antibody for WB - ABIN658088 : Nakatsu, Sakoda, Kushiyama, Ono, Fujishiro, Horike, Yoneda, Ohno, Tsuchiya, Kamata, Tahara, Isobe, Nishimura, Katagiri, Oka, Fukushima, Takahashi, Kurihara, Uchida, Asano: Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity. in The Journal of biological chemistry 2010 (PubMed)
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  3. Human Polyclonal CRTC2 Primary Antibody for IHC (p), WB - ABIN658242 : Kaizuka, Hara, Oshiro, Kikkawa, Yonezawa, Takehana, Iemura, Natsume, Mizushima: Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly. in The Journal of biological chemistry 2010 (PubMed)
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  4. Human Polyclonal CRTC2 Primary Antibody for ICC, IF - ABIN256688 : Jeanneteau, Lambert, Ismaili, Bath, Lee, Garabedian, Chao: BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
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  5. Human Polyclonal CRTC2 Primary Antibody for IF (p), IHC (p) - ABIN745988 : Tian, Zhao, Sun, Zhi, Cheng, Zhou, Hu: CRTC2 enhances HBV transcription and replication by inducing PGC1? expression. in Virology journal 2014 (PubMed)
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  6. Human Polyclonal CRTC2 Primary Antibody for ICC, IF - ABIN151246 : Liu, Coello, Grinevich, Aguilera: Involvement of transducer of regulated cAMP response element-binding protein activity on corticotropin releasing hormone transcription. in Endocrinology 2010 (PubMed)

更多抗CRTC2的相互作用对抗体

Human CREB Regulated Transcription Coactivator 2 (CRTC2) interaction partners

  1. CRTC2 polymorphism as a risk factor for the incidence of metabolic syndrome in transplant recipients after solid organ transplantation.

  2. CRTC2 strongly enhances GR-induced transcriptional activity of glucocorticoid-responsive genes.

  3. Our results establish a role for CRTC2 as a lymphoma tumor suppressor gene

  4. the high expression of CRTC2 and PROM1 may play an important role in the occurrence and hereditary, and also advance the potential pathways that integrate genetic variants in the development of NSCLC.

  5. The data from the current study demonstrated novel PROM1 and CRTC2 mutations, which could promote lung cancer development.

  6. These results clearly indicate that non-phosphorylated CRTC2 strongly enhances hepatitis b virus biosynthesis through inducing PGC1alpha expression.

  7. Phosphorylation of CRTC2 at its AMPK (显示 PRKAA1 抗体) target site, Ser (显示 SIGLEC1 抗体) 171, dictated its subcellular localization, and the activation of aromatase (显示 CYP19A1 抗体) PII in preadipocytes.

  8. CRTC2 enhances CREB (显示 CREB1 抗体) phosphorylation through an association with the protein arginine methyltransferase 5 (PRMT5 (显示 PRMT5 抗体)).

  9. Mechanism of CREB (显示 CREB1 抗体) recognition and coactivation by the CREB (显示 CREB1 抗体)-regulated transcriptional coactivator CRTC2

  10. The lipogenic effects of GIP (显示 GIP 抗体) in the presence of insulin (显示 INS 抗体) are therefore at least partially mediated by upregulation of adipocyte LPL (显示 LCP1 抗体) gene transcription through a pathway involving PI3-K (显示 PIK3CA 抗体)/PKB (显示 AKT1 抗体)/AMPK (显示 PRKAA1 抗体)-dependent CREB (显示 CREB1 抗体)/TORC2 activation.

Mouse (Murine) CREB Regulated Transcription Coactivator 2 (CRTC2) interaction partners

  1. CRTC2 play a role in hepatic cholesterol synthesis through SREBP-2 (显示 SREBF2 抗体).

  2. Catecholaminergic deletion of Rictor (显示 RICTOR 抗体) increases water, sucrose, and morphine intake but not preference in a two-bottle choice assay in stress-naive mice, and these effects are maintained after stress. Ventral Tegmental Area-specific knockout of Rictor (显示 RICTOR 抗体) increases water and sucrose intake after physical CSDS, but does not alter consummatory behavior in the absence of stress.

  3. Three mouse CRTCs (Crtc1 (显示 CRTC1 抗体), Crtc2 and Crtc3 (显示 CRTC3 抗体)) exhibit distinct patterns of 14-3-3 (显示 YWHAQ 抗体) binding at three conserved sites corresponding to S70, S171 (显示 NUMB 抗体), and S275 (in CRTC2).

  4. the protein expression of adipose tissue CRTC 2 was reduced in mice with a combined application of change to general diet and exercise. In addition, while the protein expressions of lipase (显示 LIPG 抗体) ATGL (显示 PNPLA2 抗体) and HSL (显示 LIPE 抗体) were reduced in the mice fed with the high fat diet continually after obesity was induced

  5. CRTC2 promotes Th17 cell differentiation via stimulation of IL-17A (显示 IL17A 抗体) and IL-17F (显示 IL17F 抗体) expression by binding to CREB (显示 CREB1 抗体) over both promoters. CRTC2-mutant mice have decreased Th17 cells, and they are protected from experimental autoimmune encephalitis.

  6. chronic increases in CRTC2 activity in the liver are indeed sufficient to promote hepatic insulin (显示 INS 抗体) resistance and to disrupt glucose homeostasis

  7. cAMP, SIK (显示 SIK1 抗体) and CRTC mediate StAR expression through activation of individual StAR gene loci.

  8. RICTOR (显示 RICTOR 抗体)/mTORC2 is important for interactions between vasculature, adipocytes, and brain to tune physiological outcomes, such as blood pressure and locomotor activity.

  9. CREB regulated transcription coactivator 2 (CRTC2) functions as a mediator of mTOR (显示 FRAP1 抗体) signalling to modulate COPII-dependent SREBP1 (显示 SREBF1 抗体) processing

  10. Translational activation of CREB (显示 CREB1 抗体) is caused by elevated phospho-elF2alpha (显示 EIF2S1 抗体).

CRTC2 抗原简介

Antigen Summary

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.

Alternative names and synonyms associated with CRTC2

  • CREB regulated transcription coactivator 2 (CRTC2) 抗体
  • CREB regulated transcription coactivator 2 (LOC100358960) 抗体
  • CREB regulated transcription coactivator 2 (Crtc2) 抗体
  • 4632407F12Rik 抗体
  • CRTC2 抗体
  • mTORC2 抗体
  • RGD1308903 抗体
  • TORC-2 抗体
  • Torc2 抗体

Protein level used designations for CRTC2

CREB regulated transcription coactivator 2 , CREB-regulated transcription coactivator 2 , CREB-regulated transcription coactivator 2-like , transducer of regulated cAMP response element-binding protein (CREB) 2 , TORC-2 , transducer of CREB protein 2 , transducer of regulated cAMP response element-binding protein 2

GENE ID SPECIES
612305 Canis lupus familiaris
715908 Macaca mulatta
100056571 Equus caballus
100151904 Sus scrofa
100358960 Oryctolagus cuniculus
100472270 Ailuropoda melanoleuca
100019951 Monodelphis domestica
100597840 Nomascus leucogenys
200186 Homo sapiens
74343 Mus musculus
310615 Rattus norvegicus
540959 Bos taurus
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