MICA 蛋白 (MICA)产品概述

Full name:
MHC Class I Polypeptide-Related Sequence A 蛋白 (MICA)
在www.antibodies-online.cn可供18 MHC Class I Polypeptide-Related Sequence A (MICA) 蛋白的8不同的供货商。 再加上,我们可以发MICA 抗体 (152)MICA 试剂盒 (31)和数多这个蛋白质的别的产品。 总共213 MICA产品已列进来了。
FLJ60820, Ica, MGC111087, MIC-A, mICA, PERB11.1
列出全部蛋白 基因 基因ID UniProt
小鼠 MICA MICA 71775 Q9DBD0
MICA 4276  


按照种类MICA 蛋白 (MICA)


引用最多的MICA 蛋白

  1. Human MICA Protein expressed in HEK-293 Cells - ABIN2181502 : Groh, Steinle, Bauer, Spies: Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 3 references for 2181502

  2. Human MICA Protein expressed in Human Cells - ABIN2005167 : Xiang, Liu, Zheng, Liu, Lv, Gao, Hu, Lam, Chan, Yang, Chen, Tsao, Bonneville, Lau, Tu: Targeted activation of human V?9V?2-T cells controls epstein-barr virus-induced B cell lymphoproliferative disease. in Cancer cell 2014 (PubMed)
    Show all 2 references for 2005167


Mouse (Murine) MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. Murine inhibitor of carbonic anhydrase was a glycoprotein that associated with carbonic anhydrase in a 1:1 stoichiometry.[ICA]

Human MHC Class I Polypeptide-Related Sequence A (MICA) interaction partners

  1. New truncated MICA isoforms exhibit a range of functions that may drive unexpected immune mechanisms and provide new tools for immunotherapy

  2. data reveal that MICA and PVR (显示 PVR 蛋白) are directly regulated by human cytomegalovirus immediate early (显示 JUN 蛋白) proteins, and this may be crucial for the onset of an early host antiviral response

  3. This demonstrates for the first time that MICA/B is more broadly expressed in normal tissue and that expression is mainly intracellular with only a small fraction appearing on the cell surface of some epithelia and tumour cells.

  4. selecting a MICA-matched donor significantly influences key clinical outcomes of HCT in which a marked reduction of GVHD is paramount. The tight linkage disequilibrium between MICA and HLA-B renders identifying a MICA-matched donor readily feasible in clinical practice.

  5. MICA-129 matching is relevant in unrelated hematopoietic stem cell transplantation.

  6. No evidence of an association between MICA*Del and nasopharyngeal carcinoma in the southern Chinese Han population.

  7. These findings identify the major histocompatibility complex-related MICA as an immunogenetic factor that may functionally influence anti-BK polyomavirus immune responses and infection outcomes.

  8. This study provided information on the distribution of MICA polymorphisms and linkage disequilibrium with HLA-B alleles in Brazilian renal-transplant candidates. A total of 19 MICA allele groups were identified. The most frequent allele groups were MICA*008 (21.6%), MICA*002 (17.0%) and MICA*004 (14.8%). The most common haplotypes were MICA*009-B*51 (7.8%), MICA*004-B*44 (6.06%) and MICA*002-B*35 (5.63%).

  9. MICA*A4 protects against ulcerative colitis, whereas MICA*A5.1 is associated with abscess formation and age of onset.

  10. MICA*012:05 differs from MICA*012:01 by a single synonymous C to T substitution at nucleotide position 269 in exon



MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with MICA

  • RIKEN cDNA 1300017J02 gene (1300017J02Rik)
  • MHC class I polypeptide-related sequence A (MICA)
  • FLJ60820 蛋白
  • Ica 蛋白
  • MGC111087 蛋白
  • MIC-A 蛋白
  • mICA 蛋白
  • PERB11.1 蛋白

Protein level used designations for MICA

inhibitor of carbonic anhydrase , MHC class I polypeptide-related sequence A , HLA class I antigen , Stress inducible class I homolog , MHC class I chain-related protein A , MHC class I chain-related gene A protein , stress inducible class I homolog , F10 alpha chain-like , class I histocompatibility antigen

71775 Mus musculus
4276 Homo sapiens
100507436 Homo sapiens
417067 Gallus gallus
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