BAFF and Receptor Detection Set
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- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
- 纯化方法
- Antibodies are supplied as affinity chromatography purified IgG.
- 组件
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BAFF Antibody, (50 μg)
APRIL Antibody, (50 μg)
TACI Antibody, (50 μg)
BCMA Antibody, (50 μg)
BAFF-R Antibody, (50 μg)
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- 应用备注
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These polyclonal antibodies can be used for detection of BAFF and its receptors by Western blot at 2 μg/mL to 1 μg/mL, Immunohistochemistry, and Immunoflourescence. Whole cell lysate from HepG2 cells can be used as a positive control for each antibody except BAFF-R antibody, murine spleen lysate can be used as a positive control for that.
Optimal dilutions for each application to be determined by the researcher. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Stable at 4 °C for three months, store at -20 °C for up to one year.
- 有效期
- 12 months
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- 背景
- Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members were recently identified by several groups and designated BAFF and APRIL. Both proteins stimulate B cell proliferation, humoral immune responses, NF-κB activation, and apoptosis. Two receptors, TACI and BCMA, recognize both BAFF and APRIL, a third receptor, BAFF-R, is specific for BAFF. These ligands and their receptors are involved in the development of autoimmune diseases as well as cancer.
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