Gly-Arg-Cys3-Cys4-His-Pro-Ala-Cys8-Gly-Lys-Asn-Tyr-Ser-Cys14-NH2Disulfide bonds between Cys3-Cys8 and Cys4-Cys14
限制
仅限研究用
抗原
alpha-conotoxin MI
背景
Alpha-conotoxin MI has been isolated from the venom of the cone snail Conus magus. This conotoxin acts on postsynaptic membranes. It binds onto and blocks nicotinic acetylcholine receptors (nAChR). alpha-conotoxin MI blocks mammalian nAChR composed of alpha1/delta subunits with high potency and alpha1/gamma with low potency.