anti-Tubulin Folding Cofactor E (TBCE) 抗体

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. 再加上,我们可以发TBCE 蛋白 (6)TBCE 试剂盒 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TBCE 70430 Q8CIV8
TBCE 6905 Q15813
TBCE 361255 Q5FVQ9

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Showing 10 out of 50 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 EIA, WB TBCE Antibody (Center) western blot analysis in CEM,K562 cell line lysates (35µg/lane).This demonstrates the TBCE antibody detected the TBCE protein (arrow). 0.4 mL Log in to see 29至35个工作日
¥4,086.26
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非结合性 WB TBCE Antibody (Center) (ABIN653623) western blot analysis in CEM,K562 cell line lysates (35 µg/lane).This demonstrates the TBCE antibody detected the TBCE protein (arrow). 400 μL Log in to see 5至8个工作日
¥2,325.14
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Cow 非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
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小鼠 非结合性 WB Western Blot analysis of TBCE expression in transfected 293T cell line by TBCE MaxPab polyclonal antibody.Lane 1: TBCE transfected lysate(57.97 KDa).Lane 2: Non-transfected lysate. TBCE MaxPab polyclonal antibody. Western Blot analysis of TBCE expression in human spleen. 50 μg Log in to see 29至34个工作日
¥3,169.73
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非结合性 ICC, IF, IHC, IHC (p), WB   0.1 mL Log in to see 28至35个工作日
¥3,591.24
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小鼠 非结合性 IHC, WB Immunohistochemistry: PAC2 Antibody (1E8) [NBP2-45438] - Analysis of Carcinoma of Human thyroid tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) Immunohistochemistry: PAC2 Antibody (1E8) [NBP2-45438] - Analysis of Human Kidney tissue. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120C for 3 min) 0.1 mL Log in to see 26至33个工作日
¥3,655.56
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非结合性 IHC, WB Western blot analysis of extracts of various cell lines, using TBCE antibody. 100 μL Log in to see 34至38个工作日
¥2,882.69
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非结合性 IP, WB Immunoprecipitation of TBCE transfected lysate using anti-TBCE MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with TBCE purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of TBCE expression in transfected 293T cell line by TBCE MaxPab polyclonal antibody.Lane 1: TBCE transfected lysate(59.30 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 29至34个工作日
¥3,073.67
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非结合性 IHC, IHC (p) Immunohistochemistry: PAC2 Antibody [NBP2-30576] - Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in cells in tubules. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
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非结合性 ICC, IF, IHC, IHC (p) Immunohistochemistry: PAC2 Antibody [NBP2-30574] - Immunohistochemical staining of human kidney shows strong luminal membranous positivity in renal tubules. Immunocytochemistry/Immunofluorescence: PAC2 Antibody [NBP2-30574] - Staining of human cell line U-251 MG shows positivity in nucleus. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
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通过反应活性、应用领域、克隆类型和共轭标记 TBCE 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-TBCE 抗体

  1. Human Polyclonal TBCE Primary Antibody for WB - ABIN653623 : Biernacki, Marina, Zhang, Liu, Bruns, Cai, Neuberg, Canning, Alyea, Soiffer, Brusic, Ritz, Wu: Efficacious immune therapy in chronic myelogenous leukemia (CML) recognizes antigens that are expressed on CML progenitor cells. in Cancer research 2010 (PubMed)
    Show all 5 references for 653623

  2. Human Polyclonal TBCE Primary Antibody for EIA, WB - ABIN955104 : Padidela, Kelberman, Press, Al-Khawari, Hindmarsh, Dattani: Mutation in the TBCE gene is associated with hypoparathyroidism-retardation-dysmorphism syndrome featuring pituitary hormone deficiencies and hypoplasia of the anterior pituitary and the corpus callosum. in The Journal of clinical endocrinology and metabolism 2009 (PubMed)
    Show all 3 references for 955104

  3. Human Polyclonal TBCE Primary Antibody for WB - ABIN520724 : Bellouze, Schäfer, Buttigieg, Baillat, Rabouille, Haase: Golgi fragmentation in pmn mice is due to a defective ARF1/TBCE cross-talk that coordinates COPI vesicle formation and tubulin polymerization. in Human molecular genetics 2014 (PubMed)

  4. Human Polyclonal TBCE Primary Antibody for ICC, IF - ABIN4358010 : Sferra, Baillat, Rizza, Barresi, Flex, Tasca, DAmico, Bellacchio, Ciolfi, Caputo, Cecchetti, Torella, Zanni, Diodato, Piermarini, Niceta, Coppola, Tedeschi, Martinelli, Dionisi-Vici, Nigro et al.: TBCE Mutations Cause Early-Onset Progressive Encephalopathy with Distal Spinal Muscular Atrophy. ... in American journal of human genetics 2016 (PubMed)

更多抗TBCE的相互作用对抗体

Human Tubulin Folding Cofactor E (TBCE) interaction partners

  1. Although loss of function of TBCE has been documented to impact multiple developmental processes, the present findings provide evidence that hypomorphic TBCE mutations primarily drive neurodegeneration

  2. Sanjad-Sakati syndrome molecular pathology has been shown to be due to mutations in the TBCE gene on chromosome 1q42-q43.

  3. the role of the human TBCE and TBCB (显示 TBCB 抗体) chaperones in alpha-tubulin (显示 TUBA4A 抗体)-beta-tubulin (显示 TUBB 抗体) dissociation, was investigated.

  4. tudies confirmed elevated expression of three target antigens RAB38, TBCE, and DUSP12 in CML.

  5. TBCE has a role in membrane trafficking in the Golgi and late endosomal compartments, tubulin (显示 TUBB 抗体) assembly, and the development of the parathyroid

  6. Tbce is critical for the maintenance of microtubules in mouse motor axons

  7. The tubulin-specific chaperone E (Tbce) mutation described here suggests that alterations in tubulin (显示 TUBB 抗体) assembly lead to retrograde degeneration of motor axons, ultimately resulting in motoneuron cell death.

  8. Reviews recent findings on the molecular mechanisms of the development of the parathyroid glands, with special emphasis on the possible role of tubulin chaperone E (TBCE), implicated in the hypopathyroidism, retardation and dysmorphism (HRD) syndrome.

  9. TBCE, TBCB (显示 TBCB 抗体) and alpha-tubulin (显示 TUBA4A 抗体) form a ternary complex after heterodimer dissociation. These complexes might serve to escort alpha-tubulin (显示 TUBA4A 抗体) towards degradation or recycling, depending on the cell requirements.

  10. Depletion of Op18 (显示 STMN1 抗体) by means of RNA interference increased the susceptibility of tubulin (显示 TUBB 抗体) to TBCE or E-like (显示 TBCEL 抗体) mediated disruption, while overexpressed Op18 (显示 STMN1 抗体) exerted a tubulin (显示 TUBB 抗体)-protective effect.

Mouse (Murine) Tubulin Folding Cofactor E (TBCE) interaction partners

  1. ARF1 (显示 ARF1 抗体)/TBCE-mediated cross-talk that coordinates COPI formation and tubulin (显示 TUBB 抗体) polymerization at the Golgi.

  2. We conclude from our study that the mutation of the TBCE gene affects the auditory nerve and the cochlear hair cells simultaneously, leading to progressive hearing loss

  3. Tbce is critical for the maintenance of microtubules in mouse motor axons

TBCE 抗原简介

蛋白简介

Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex\; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with TBCE

  • tubulin-specific chaperone E (Tbce) 抗体
  • tubulin folding cofactor E (TBCE) 抗体
  • tubulin folding cofactor E (Tbce) 抗体
  • 2610206D02Rik 抗体
  • C530005D02Rik 抗体
  • HRD 抗体
  • KCS 抗体
  • KCS1 抗体
  • pac2 抗体
  • pmn 抗体

Protein level used designations for TBCE

progressive motor neuropathy , tubulin-folding cofactor E , Kenny-Caffey syndrome , tubulin-specific chaperone E , beta-tubulin cofactor E

GENE ID SPECIES
70430 Mus musculus
6905 Homo sapiens
361255 Rattus norvegicus
505066 Bos taurus
100172438 Pongo abelii
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