TNF Receptor-Associated Protein 1 (TRAP1) ELISA试剂盒

HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. 再加上,我们可以发TNF Receptor-Associated Protein 1 抗体 (174)TNF Receptor-Associated Protein 1 蛋白 (12)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TRAP1 10131 Q12931
TRAP1 68015 Q9CQN1
TRAP1 287069 Q5XHZ0

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适于 TNF Receptor-Associated Protein 1 相互作用对的更多 ELISA 试剂盒

Human TNF Receptor-Associated Protein 1 (TRAP1) interaction partners

  1. MFSD2B, CCL20 (显示 CCL20 ELISA试剂盒) and STAT1 (显示 STAT1 ELISA试剂盒), or STARD7 and ZNF512 (显示 ZNF512 ELISA试剂盒) genes may be risk or protect factors in prognosis of ADC (显示 ADC ELISA试剂盒); HTR2B (显示 HTR2B ELISA试剂盒), DPP4 (显示 DPP4 ELISA试剂盒), and TGFBRAP1 (显示 TGFBRAP1 ELISA试剂盒) genes may be risk factors in prognosis of SQC (显示 QPCT ELISA试剂盒).

  2. TRAP1 is often deleted in high-grade serous ovarian cancer patients.

  3. TRAP1 increases cell proliferation, reduces apoptosis, and promotes cell invasion without changes in mitochondrial bioenergetics. Therefore, TRAP1 is a driver of prostate cancer in vivo and an "actionable" therapeutic target.

  4. overexpression of TRAP1 might contribute to tumor cell local invasion of colorectal cancer

  5. Increased TRAP1 expression was significantly associated with EOC stages.

  6. Overexpression of TRAP1 in breast cancer cells causes mitochondrial fusion, triggers mitochondria to form tubular networks, and suppresses cell migration and invasion in vitro and in vivo. These data link TRAP1-regulated mitochondrial dynamics and function with tumorigenesis in breast cancer.

  7. TRAP1 is highly expressed in kidney cancer and correlates with patients prognosis

  8. TRAP1 is a downstream effector of BRAF (显示 BRAF ELISA试剂盒) cytoprotective pathway in mitochondria and TRAP1 targeting may represent a novel strategy to improve the activity of proapoptotic agents in BRAF (显示 BRAF ELISA试剂盒)-driven CRC (显示 CALR ELISA试剂盒) cells.

  9. the association of rs2679860 polymorphisms of TGFBRAP1 (显示 TGFBRAP1 ELISA试剂盒) and DBP (显示 GC ELISA试剂盒) variation as well as plasma levels of TGF-beta1 (显示 TGFB1 ELISA试剂盒)

  10. Our results indicate that GRP94 (显示 HSP90B1 ELISA试剂盒) and TRAP1 might contribute more to the carcinogenesis or biology of SCLC than HSP90alpha and HSP90beta (显示 HSP90AB1 ELISA试剂盒)

Mouse (Murine) TNF Receptor-Associated Protein 1 (TRAP1) interaction partners

  1. TRAP1 increases cell proliferation, reduces apoptosis, and promotes cell invasion without changes in mitochondrial bioenergetics. Therefore, TRAP1 is a driver of prostate cancer in vivo and an "actionable" therapeutic target.

  2. Data show that the overexpression of heat shock protein 75 (Hsp75) decreased neural stem cells (NSCs) apoptosis and preserved mitochondrial membrane potential.

  3. TRAP-1-/- mice are viable and show reduced incidence of age-associated pathologies. Loss of TRAP-1 upregulates oxidative phosphorylation and glycolysis transcriptomes.

  4. overexpression of TRAP1 leads to mitochondrial aberrations, including an increase in basal ROS (显示 ROS1 ELISA试剂盒) levels and decrease in mitochondrial biogenesis, together with a decrease in peroxisome proliferator-activated receptor gamma (显示 PPARG ELISA试剂盒) coactivator-1alpha mRNA levels

  5. Early mesangial nephritis initiates a cascade of inflammatory signals that lead to up-regulation of Trap1 and a consequent down-regulation of renal DNaseI (显示 DNASE1 ELISA试剂盒) by transcriptional interference.

  6. TRAP1 regulates a metabolic switch between oxidative phosphorylation and aerobic glycolysis in immortalized mouse fibroblasts.

  7. These data identify TRAP-1 as a novel mitochondrial survival factor differentially expressed in localized and metastatic prostate cancer compared with normal prostate.

TNF Receptor-Associated Protein 1 (TRAP1) 抗原简介

Antigen Summary

This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with TRAP1

  • TNF receptor-associated protein 1 (TRAP1) 抗体
  • TNF receptor-associated protein 1 (Trap1) 抗体
  • transforming growth factor, beta receptor associated protein 1 (TGFBRAP1) 抗体
  • 2410002K23Rik 抗体
  • HSP 75 抗体
  • HSP75 抗体
  • HSP90L 抗体
  • TRAP-1 抗体
  • TRAP1 抗体

Protein level used designations for TRAP1

TNFR-associated protein 1 , heat shock protein 75 kDa, mitochondrial , tumor necrosis factor type 1 receptor-associated protein , HSP 75 , TRAP-1 , tumor necrosis factor type 1 receptor associated protein , TGF beta receptor associated protein -1 , TGF-beta receptor-associated protein 1 , transforming growth factor-beta receptor-associated protein 1

GENE ID SPECIES
10131 Homo sapiens
416666 Gallus gallus
68015 Mus musculus
287069 Rattus norvegicus
514472 Bos taurus
490032 Canis lupus familiaris
9392 Homo sapiens
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