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The protein encoded by RHAG is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. 再加上，我们可以发RHAG 抗体 (11) 和 RHAG 蛋白 (5)和数多这个蛋白质的别的产品。
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novel allele in a Brazilian pregnant woman encoding the Rhnull phenotype due to a change in RHAG exon2 c.310C>T, which leads to a premature stop codon (Gln104Stop).
We characterized ammonia and ammonium (NH3/NH4 (+)) transport by the rhesus-associated (Rh) glycoproteins RhAG, Rhbg, and Rhcg expressed in Xenopus oocytes. We used ion-selective microelectrodes and two-electrode voltage clamp to measure changes in intracellular pH, surface pH, and whole cell currents induced by NH3/NH4 (+) and methyl amine/ammonium (MA/MA(+)).
A new Rh null allele (RHAG*01N.13) of the regulator type found in a consanguineous French-speaking quebecers'family.
RhAG, RhBG and RhCG (显示 RHCG ELISA试剂盒)-exhibit significant permeability to NH3 and show for the first time that RhBG and RhCG (显示 RHCG ELISA试剂盒) can conduct CO2.
Data from differentiating cultured erythroid precursor cells suggest that RhAG knockdown abolishes Rh blood group (显示 DARC ELISA试剂盒) expression (RhoD [ras homolog family member D]; ICAM4 (显示 ICAM4 ELISA试剂盒) [intercellular adhesion molecule 4 (显示 ICAM4 ELISA试剂盒)]; CD47 Rh-related antigen (显示 CD47 ELISA试剂盒)) in erythroid cells.
Substitution of GPB (显示 GYPB ELISA试剂盒) with Gp.Mur significantly reduced the expression of Rh antigen and RhAG on the Mi.III(+/+) erythrocyte membrane
Results provide new insights into the functional impact of the Phe65Ser mutation in RhAG.
that the 672C>A missense mutation in the RHAG gene could result in Rh(null) of the regulator type, and the single-amino-acid change (Ser (显示 SIGLEC1 ELISA试剂盒) to Arg) might be critical for assembly of the Rh antigen complex within the membrane
The results provide new insight into RhAG stomatocytosis mutant F65S as a combined loss-of-function/gain-of-function mutation for methylammonium/methylammonium+ transport
Cell-surface expression of RhD (显示 RHD ELISA试剂盒) blood group (显示 DARC ELISA试剂盒) polypeptide is posttranscriptionally regulated by the RhAG glycoprotein.
RhAG expression enhanced the ammonium-induced initial alkalinization (related to NH3 influx)& secondary acidification (related to NH4+ influx). Sub-millimolar NH4+ concentrations induced inward currents in voltage-clamped RhAG-expressing cells.
Review. Rhag plays a major role in the NH3 conductance of erythrocytes, but probably not in CO2 transport.
The protein encoded by this gene is erythrocyte-specific and is thought to be part of a membrane channel that transports ammonium and carbon dioxide across the blood cell membrane. The encoded protein appears to interact with Rh blood group antigens and Rh30 polypeptides. Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN), or Rh-deficiency syndrome.
Rh blood group-associated glycoprotein
, Rhesus blood group-associated glycoprotein
, ammonium transporter Rh type A
, Rhesus associated polypeptide, 50-KD
, erythrocyte membrane glycoprotein Rh50
, erythrocyte plasma membrane 50 kDa glycoprotein
, rh family type A glycoprotein
, rh type A glycoprotein
, rhesus blood group family type A glycoprotein
, rhesus blood group-associated ammonia channel
, Erythrocyte membrane glycoprotein Rh50
, Rh family type A glycoprotein
, Rh type A glycoprotein
, Rhesus blood group family type A glycoprotein
, Rhesus blood group-associated A glycoprotein
, glycoprotein 50kD
, 50 kD glycoprotein