Prolylcarboxypeptidase (PRCP) ELISA试剂盒

The protein encoded by PRCP is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. 再加上,我们可以发Prolylcarboxypeptidase 抗体 (67)Prolylcarboxypeptidase 蛋白 (12)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
PRCP 649 P13497
PRCP 72461 Q7TMR0
PRCP 293118  

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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
大鼠 0.28 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 7至10个工作日
¥3,587.57
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0.054 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 9至11个工作日
¥4,293.90
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小鼠 9.37 pg/mL 37.5-2400 pg/mL Typical standard curve 96 Tests Log in to see 9至12个工作日
¥3,994.38
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1.0 pg/mL 50-1000 pg/mL   96 Tests Log in to see 9至12个工作日
¥3,411.38
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豚鼠 1.0 pg/mL 50-1000 pg/mL   96 Tests Log in to see 9至12个工作日
¥3,411.38
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1.0 pg/mL 50-1000 pg/mL   96 Tests Log in to see 9至12个工作日
¥3,411.38
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Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 6至8个工作日
¥5,717.40
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小鸡 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 6至8个工作日
¥5,717.40
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1.0 pg/mL 50-1000 pg/mL   96 Tests Log in to see 9至12个工作日
¥3,411.38
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Cow
  96 Tests Log in to see 9至12个工作日
¥3,411.38
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适于 Prolylcarboxypeptidase 相互作用对的更多 ELISA 试剂盒

Human Prolylcarboxypeptidase (PRCP) interaction partners

  1. Given the association of BMP1 (显示 BMP1 ELISA试剂盒)-related Osteogenesis Imperfecta (显示 COL1A2 ELISA试剂盒) (OI) with very high bone material density, concerns remain whether anti-resorptive therapy is indicated in this ultra-rare form of OI

  2. Data show that the KKN1 fragment generated by BMP1 (显示 BMP1 ELISA试剂盒)-cleavage of WFIKKN1 (显示 WFIKKN1 ELISA试剂盒) protein contributes most significantly to the observed enhancer activity.

  3. For the first time, PRCP is identified as an apelin (显示 APLN ELISA试剂盒)-cleaving enzyme.

  4. a previously unknown O-glycosylation site and Asn-hydroxylation site, indicating a novel feature of BMP-1 (显示 BMP1 ELISA试剂盒) in the EGF (显示 EGF ELISA试剂盒) domain. The study clearly outlines the benefit of in-depth characterization of overexpressed proteins to deduce important protein modifications.

  5. BMP-1 (显示 BMP1 ELISA试剂盒) accelerates the connective tissue growth factor (显示 CTGF ELISA试剂盒) production dependently on cellular internalization in human dental pulp cells, indicating a novel property of BMP-1 (显示 BMP1 ELISA试剂盒) which potentially enhances bone-like reparative dentin formation.

  6. Studies indicate crosstalk between Notch receptor and Wnt protein, Hedgehog protein, hypoxia and transforming growth factor beta (TGFbeta)/bone morphogenetic protein (BMP) pathways.

  7. study thus highlights the severe and progressive nature of BMP1 (显示 BMP1 ELISA试剂盒)-associated OI in adults and broadens insights into the functional consequences of BMP1/mTLD-deficiency on ECM (显示 MMRN1 ELISA试剂盒) organization.

  8. Data indicate that BMP-1 (显示 BMP1 ELISA试剂盒) can simultaneously trigger matrix assembly and boost the synthesis of matrix proteins via a direct effect on growth factors in the contexts of development, growth and tissue repair. [review]

  9. The decrease in PRCP levels in the first 24 h after stroke onset is associated with stroke severity and an unfavourable short-term stroke outcome

  10. Two novel variants in the BMP1 (显示 BMP1 ELISA试剂盒) gene: c.808A>G and c.1297G>T care associated with osteogenesis imperfecta (显示 COL1A2 ELISA试剂盒).

Mouse (Murine) Prolylcarboxypeptidase (PRCP) interaction partners

  1. This study demonistrated that PRCP gene is broadly expressed in the brain.

  2. PRCP regulates cell growth, angiogenesis, and the response to vascular injury

  3. ACE2 (显示 ACE2 ELISA试剂盒) metabolizes ANG II (显示 AGT ELISA试剂盒) in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.

  4. PRCP is an important regulator of energy and glucose homeostasis since its deletion significantly improves metabolic parameters in mice exposed to both standard chow diet and high-fat diet

  5. analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors

  6. This study showed that PRCP mutant mice have a significant decrease in fat mass, although an increase in lean mass was also observed; reduced leptin (显示 LEP ELISA试剂盒) levels and increased energy expenditure were also found.

  7. Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.

  8. PRCP is an important component of melanocortin signaling and weight maintenance via control of active alpha-MSH1-13 levels.

Prolylcarboxypeptidase (PRCP) 抗原简介

Antigen Summary

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with PRCP

  • prolylcarboxypeptidase (angiotensinase C) (PRCP) 抗体
  • prolylcarboxypeptidase (angiotensinase C) (prcp) 抗体
  • prolylcarboxypeptidase (AaeL_AAEL005521) 抗体
  • prolylcarboxypeptidase (CpipJ_CPIJ006123) 抗体
  • prolylcarboxypeptidase (CpipJ_CPIJ006124) 抗体
  • bone morphogenetic protein 1 (BMP1) 抗体
  • prolylcarboxypeptidase (angiotensinase C) (Prcp) 抗体
  • 2510048K03Rik 抗体
  • 2610104A14Rik 抗体
  • AI451719 抗体
  • HUMPCP 抗体
  • MGC145178 抗体
  • OI13 抗体
  • PCOLC 抗体
  • PCP 抗体
  • PCP2 抗体
  • TLD 抗体

Protein level used designations for PRCP

prolylcarboxypeptidase , mammalian tolloid protein , procollagen C-endopeptidase , procollagen C-proteinase , lysosomal Pro-X carboxypeptidase , proline carboxypeptidase , angiotensinase C , lysosomal carboxypeptidase C , prolylcarboxypeptidase isoform 1 preproprotein

GENE ID SPECIES
100061830 Equus caballus
780095 Xenopus (Silurana) tropicalis
5579822 Aedes aegypti
6038068 Culex quinquefasciatus
6038069 Culex quinquefasciatus
649 Homo sapiens
72461 Mus musculus
5547 Homo sapiens
476788 Canis lupus familiaris
534927 Bos taurus
293118 Rattus norvegicus
100734342 Cavia porcellus
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