Use your antibodies-online credentials, if available.
The protein encoded by PRCP is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. 再加上，我们可以发Prolylcarboxypeptidase 抗体 (67) 和 Prolylcarboxypeptidase 蛋白 (12)和数多这个蛋白质的别的产品。
Showing 10 out of 41 products:
Given the association of BMP1 (显示 BMP1 ELISA试剂盒)-related Osteogenesis Imperfecta (显示 COL1A2 ELISA试剂盒) (OI) with very high bone material density, concerns remain whether anti-resorptive therapy is indicated in this ultra-rare form of OI
Data show that the KKN1 fragment generated by BMP1 (显示 BMP1 ELISA试剂盒)-cleavage of WFIKKN1 (显示 WFIKKN1 ELISA试剂盒) protein contributes most significantly to the observed enhancer activity.
For the first time, PRCP is identified as an apelin (显示 APLN ELISA试剂盒)-cleaving enzyme.
a previously unknown O-glycosylation site and Asn-hydroxylation site, indicating a novel feature of BMP-1 (显示 BMP1 ELISA试剂盒) in the EGF (显示 EGF ELISA试剂盒) domain. The study clearly outlines the benefit of in-depth characterization of overexpressed proteins to deduce important protein modifications.
BMP-1 (显示 BMP1 ELISA试剂盒) accelerates the connective tissue growth factor (显示 CTGF ELISA试剂盒) production dependently on cellular internalization in human dental pulp cells, indicating a novel property of BMP-1 (显示 BMP1 ELISA试剂盒) which potentially enhances bone-like reparative dentin formation.
Studies indicate crosstalk between Notch receptor and Wnt protein, Hedgehog protein, hypoxia and transforming growth factor beta (TGFbeta)/bone morphogenetic protein (BMP) pathways.
study thus highlights the severe and progressive nature of BMP1 (显示 BMP1 ELISA试剂盒)-associated OI in adults and broadens insights into the functional consequences of BMP1/mTLD-deficiency on ECM (显示 MMRN1 ELISA试剂盒) organization.
Data indicate that BMP-1 (显示 BMP1 ELISA试剂盒) can simultaneously trigger matrix assembly and boost the synthesis of matrix proteins via a direct effect on growth factors in the contexts of development, growth and tissue repair. [review]
The decrease in PRCP levels in the first 24 h after stroke onset is associated with stroke severity and an unfavourable short-term stroke outcome
Two novel variants in the BMP1 (显示 BMP1 ELISA试剂盒) gene: c.808A>G and c.1297G>T care associated with osteogenesis imperfecta (显示 COL1A2 ELISA试剂盒).
This study demonistrated that PRCP gene is broadly expressed in the brain.
PRCP regulates cell growth, angiogenesis, and the response to vascular injury
ACE2 (显示 ACE2 ELISA试剂盒) metabolizes ANG II (显示 AGT ELISA试剂盒) in the kidney at neutral and basic pH, while prolylcarboxypeptidase catalyzes the same reaction at acidic pH.
PRCP is an important regulator of energy and glucose homeostasis since its deletion significantly improves metabolic parameters in mice exposed to both standard chow diet and high-fat diet
analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors
This study showed that PRCP mutant mice have a significant decrease in fat mass, although an increase in lean mass was also observed; reduced leptin (显示 LEP ELISA试剂盒) levels and increased energy expenditure were also found.
Murine prolylcarboxypeptidase depletion induces vascular dysfunction with hypertension and faster arterial thrombosis.
PRCP is an important component of melanocortin signaling and weight maintenance via control of active alpha-MSH1-13 levels.
The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
, mammalian tolloid protein
, procollagen C-endopeptidase
, procollagen C-proteinase
, lysosomal Pro-X carboxypeptidase
, proline carboxypeptidase
, angiotensinase C
, lysosomal carboxypeptidase C
, prolylcarboxypeptidase isoform 1 preproprotein