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Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA. 再加上，我们可以发PLAGL2 蛋白 (3)和数多这个蛋白质的别的产品。
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Our findings indicated that PLAGL2 might be a very upstream key molecule regulating Epithelial-mesenchymal transition involved in Wnt (显示 WNT2 抗体)/bcatenin signaling pathway in Colorectal adenocarcinoma
PLAGL2 expression induces lamellipodia formation and disruption of stress fiber formation.
PLAGL2 regulate cell cycle and apoptosis via activation of the p53 (显示 TP53 抗体) family member, p73 (显示 TP73 抗体), in human promonocytic U937 cells.
Transcriptome analysis revealed that these differentiation-suppressive activities are attributable in part to PLAGL2 modulation of Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling
The data identify PC2 (显示 KRT6B 抗体) as a novel PLAGL2-binding protein and important mediator of PLAGL2 transactivation.
PLAGL2 may modulate SP-C (显示 SFTPC 抗体) expression during lung development.
Plag1 (显示 PLAG1 抗体) and Plagl2 are novel leukemia oncogenes that act by expanding hematopoietic progenitors expressing CbF beta (显示 CBFB 抗体)-SMMHC (显示 MYH11 抗体).
These data clearly identify PLAGL2 as a novel regulator of NCF2/p67phox (显示 NCF2 抗体) gene expression as well as NADPH oxidase (显示 NOX1 抗体) activity and contribute to a greater understanding of the transcriptional regulation of NCF2 (显示 NCF2 抗体).
Coexpression of Tip60 (显示 KAT5 抗体) and PLAGL2 completely abolishes the sumoylation of PLAGL2.
Nuclear PLAGL2 occupied and transactivated the endogenous SP-C (显示 SFTPC 抗体) promoter in hypoxic lung cells.These results further suggest that PLAGL2 is an oxidative stress responding regulator in lung cells.
induces the expression of a proapoptotic protein Nip3, leading to cellular apoptosis.
PlagL2 regulates important aspects of dietary lipid absorption, and the PlagL2(-/-) animal model has implications for the amelioration of obesity and the metabolic syndrome.
Increased cell injury and/or death could be caused directly by the upregulation of bNip3 (显示 BNIP3 抗体), a preapoptotic molecule that dimerizes with Bcl-2 (显示 BCL2 抗体), or indirectly by the aberrant expression of SP-C (显示 SFTPC 抗体)-induced endoplasmic reticulum stress in epithelial cells.
Pleiomorphic adenoma gene-like 2 is a zinc-finger protein that recognizes DNA and/or RNA.
zinc finger protein PLAGL2
, pleiomorphic adenoma gene-like 2
, zinc finger protein PLAGL2-like
, C2H2-type zinc finger protein
, pleiomorphic adenoma-like protein 2
, pleomorphic adenoma gene like 2