Peptidylprolyl Isomerase B (Cyclophilin B) 蛋白 (PPIB)

The protein encoded by PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. 再加上,我们可以发Peptidylprolyl Isomerase B (Cyclophilin B) 抗体 (123)Peptidylprolyl Isomerase B (Cyclophilin B) 试剂盒 (54)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
PPIB 19035 P24369
PPIB 64367 P24368
PPIB 5479 P23284
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大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,331.68
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大肠杆菌(E. Coli) 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
$4,331.68
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HEK-293 Cells His tag Human PPIB, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 2至3个工作日
$264.00
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人细胞 His tag 100 μg Log in to see 20至21个工作日
$382.80
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大肠杆菌(E. Coli) 非结合性 100 μg Log in to see 2至3个工作日
$270.00
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大肠杆菌(E. Coli) 非结合性 100 μg Log in to see 15至19个工作日
$242.00
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大肠杆菌(E. Coli) His tag 100 μg Log in to see 15至18个工作日
$576.00
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大肠杆菌(E. Coli) 小鼠 His tag 100 μg Log in to see 15至18个工作日
$672.00
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HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10至12个工作日
$785.40
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小麦胚 GST tag 10 μg Log in to see 11至12个工作日
$405.71
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PPIB 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Rat (Rattus) ,

Human , , , , ,
, ,

引用最多的Peptidylprolyl Isomerase B (Cyclophilin B) 蛋白

  1. Human PPIB Protein expressed in Human Cells - ABIN2003709 : Chi, Valencia, Hu, Watabe, Yamaguchi, Mangini, Huang, Canfield, Cheng, Yang, Abe, Yamagishi, Shabanowitz, Hearing, Wu, Appella, Hunt: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. in Journal of proteome research 2006 (PubMed)
    Show all 3 Pubmed References

更多Peptidylprolyl Isomerase B (Cyclophilin B) (PPIB)互动伙伴

Horse (Equine) Peptidylprolyl Isomerase B (Cyclophilin B) (PPIB) interaction partners

  1. Data indicate that the mutation in cyclophilin B (CypB) locally rearranges the flexible N-terminal end of the polypeptide chain and also makes it more rigid.

  2. Mutation in cyclophilin B that causes hyperelastosis cutis in American Quarter Horse does not affect peptidylprolyl cis-trans isomerase (显示 PPIL2 蛋白) activity but shows altered cyclophilin B-protein (显示 LEPREL2 蛋白) interactions and affects collagen folding

  3. The prevalence of a previously described mutation in cyclophilin B (a causal candidate gene for hereditary equine regional dermal asthenia) among Quarter Horses in France was determined to be 1.6%.

  4. A missense mutation in cyclophilin B (PPIB) is reported as a novel, causal candidate gene for hereditary equine regional dermal asthenia (HERDA).

Mouse (Murine) Peptidylprolyl Isomerase B (Cyclophilin B) (PPIB) interaction partners

  1. These studies demonstrate novel consequences of the indirect regulatory effect of CyPB on collagen hydroxylation, impacting collagen glycosylation, crosslinking and fibrillogenesis

  2. An additional function of the rough endoplasmic reticulum protein complex prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B: the CXXXC motif reveals disulfide isomerase activity in vitro.

  3. Cyclophilin B activity regulated secretion and activity of ADAMTS13 (显示 ADAMTS13 蛋白).

  4. These data provide significant new mechanistic insight into the pathophysiology of Osteogenesis Imperfecta (显示 COL1A2 蛋白) and reveal how the members of the P3H1 (显示 LEPRE1 蛋白)/CRTAP (显示 CRTAP 蛋白)/CypB complex interact to direct proper formation of collagen and bone.

  5. These results suggest that immunophilins are involved in the complex protein networks operating at the presynaptic level and implicate the interaction between cyclophilin B and synapsins in presynaptic function.

  6. The protein identified was cyclophilin (显示 PPIE 蛋白) (Ppib).

Human Peptidylprolyl Isomerase B (Cyclophilin B) (PPIB) interaction partners

  1. observed changes in activity of six rER-resident PPIases, cyclophilin B (encoded by the PPIB gene), FKBP13 (FKBP2 (显示 FKBP2 蛋白)), FKBP19 (FKBP11 (显示 FKBP11 蛋白)), FKBP22 (FKBP14 (显示 FKBP14 蛋白)), FKBP23 (FKBP7 (显示 FKBP7 蛋白)), and FKBP65 (FKBP10 (显示 FKBP10 蛋白)), due to posttranslational modifications of proline residues in the substrate.

  2. The data suggest that overexpressed CypB protects neuronal cells from MPP+-induced dopaminergic neuronal cell death

  3. This study enhances our knowledge about the mutational pattern of the LEPRE1 (显示 LEPRE1 蛋白), CRTAP (显示 CRTAP 蛋白), and PPIB genes. LEPRE1 (显示 LEPRE1 蛋白) should be the first gene analyzed in mutation detection studies in patients with recessive OI.

  4. Over-expression of CypB enhances HIV infection by increasing nuclear import of viral DNA.

  5. Cyclophilin B has a high diagnostic value for stomach cancer and its downregulation can effectively inhibit the growth of stomach cancer cells. Thus, cyclophilin B may be a potential therapeutic target for stomach cancer treatment

  6. The extracellular portion of cyclophilin B probably plays an important role in human diseases associated with acute or chronic inflammation

  7. Findings demonstrate that CypB prevents hypoxia-induced cell death through modulation of ubiquitin-mediated CHOP (显示 DDIT3 蛋白) protein degradation, suggesting that CypB may have an important role in the tight regulation of CHOP (显示 DDIT3 蛋白) under hypoxia.

  8. These findings establish cyclophilin C (显示 PPIC 蛋白) as an ER cyclophilin (显示 PPIA 蛋白), demonstrate the novel involvement of cyclophilins B and C in ER redox homeostasis

  9. Cyclophilin B is a novel MDM2 (显示 MDM2 蛋白) interacting partner.

  10. cyclophilin B (CypB) is a prolyl isomerase residing in the endoplasmic reticulum (ER), that provides an essential survival signal in glioblastoma multiforme cells through myc (显示 MYC 蛋白) and mutant p53 (显示 TP53 蛋白)

蛋白简介Peptidylprolyl Isomerase B (Cyclophilin B) (PPIB)

蛋白简介

The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

Gene names and symbols associated with PPIB

  • peptidylprolyl isomerase B (ppib)
  • peptidylprolyl isomerase B (PPIB)
  • peptidylprolyl isomerase B (Ppib)
  • peptidylprolyl isomerase B (CC1G_03223)
  • peptidylprolyl isomerase B (cyclophilin B) (Ppib)
  • peptidylprolyl isomerase B L homeolog (ppib.L)
  • peptidylprolyl isomerase B (cyclophilin B) (PPIB)
  • peptidylprolyl isomerase B (cyclophilin B) (ppib)
  • AA408962 蛋白
  • AA553318 蛋白
  • ACYPI004891 蛋白
  • AI844835 蛋白
  • cb87 蛋白
  • Cphn-2 蛋白
  • Cphn2 蛋白
  • CyP-20b 蛋白
  • CYP-S1 蛋白
  • CYPB 蛋白
  • OI9 蛋白
  • Ppib 蛋白
  • sb:cb87 蛋白
  • SCYLP 蛋白
  • wu:fa97f08 蛋白
  • zgc:73214 蛋白
  • zgc:86796 蛋白

Protein level used designations for PPIB

cyclophilin B , peptidylprolyl isomerase B , peptidylprolyl isomerase B (cyclophilin B) , PPIase B , peptidyl-prolyl cis-trans isomerase B , Peptidyl-prolyl cis-trans isomerase B , CYP-S1 , S-cyclophilin , SCYLP , rotamase B , S-cyclophylin , cyclophilin-like protein

GENE ID SPECIES
549817 Xenopus (Silurana) tropicalis
706757 Macaca mulatta
733019 Bombyx mori
747801 Pan troglodytes
6007130 Coprinopsis cinerea okayama7130
100066834 Equus caballus
100163834 Acyrthosiphon pisum
100195841 Salmo salar
552033 Apis mellifera
100009021 Oryctolagus cuniculus
554319 Ovis aries
19035 Mus musculus
64367 Rattus norvegicus
5479 Homo sapiens
380197 Xenopus laevis
396447 Gallus gallus
478337 Canis lupus familiaris
281419 Bos taurus
406292 Danio rerio
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