anti-Neutral Cholesterol Ester Hydrolase 1 (NCEH1) 抗体

Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. 再加上,我们可以发NCEH1 蛋白 (10)NCEH1 试剂盒 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
NCEH1 57552 Q6PIU2
NCEH1 320024 Q8BLF1
NCEH1 294930 B2GV54

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Showing 10 out of 36 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB 100 μL Log in to see 24至29个工作日
¥3,074.65
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非结合性 ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: AADACL1 Antibody [NBP1-90294] - Immunohistochemical staining of human hippocampus shows strong cytoplasmic positivity in neuronal cells. Immunocytochemistry/Immunofluorescence: AADACL1 Antibody [NBP1-90294] - Human cell line. 0.1 mL Log in to see 28至35个工作日
¥3,591.24
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山羊 非结合性 ELISA, WB   100 μg Log in to see 24至29个工作日
¥6,589.10
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山羊 非结合性 ELISA   0.1 mg Log in to see 25至31个工作日
¥2,594.28
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Bat 非结合性 WB 50 μg Log in to see 29至35个工作日
¥5,538.93
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Bat 山羊 非结合性 ELISA   100 μg Log in to see 29至35个工作日
¥5,127.12
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小鼠 非结合性 WB Western Blot: AADACL1 Antibody [NBP1-79318] - Mouse Kidney lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 26至33个工作日
¥3,655.56
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山羊 非结合性 ELISA, WB   0.1 mg Log in to see 24至29个工作日
¥4,432.21
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非结合性 WB Aadacl1 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 28至34个工作日
¥11,910.48
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Cow 非结合性 WB   100 μL Log in to see 24至29个工作日
¥3,074.65
详细

通过反应活性、应用领域、克隆类型和共轭标记 NCEH1 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus)


引用最多的anti-NCEH1 抗体

  1. Dog (Canine) Polyclonal NCEH1 Primary Antibody for ELISA - ABIN408632 : Chiang, Niessen, Saghatelian, Cravatt: An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling. in Chemistry & biology 2006 (PubMed)

  2. Human Polyclonal NCEH1 Primary Antibody for ICC, IF - ABIN4277093 : Mei, Gu, Ward, Yang, Guo, He, Liu, Cao: p38 mitogen-activated protein kinase (MAPK) promotes cholesterol ester accumulation in macrophages through inhibition of macroautophagy. in The Journal of biological chemistry 2012 (PubMed)

更多抗NCEH1的相互作用对抗体

Human Neutral Cholesterol Ester Hydrolase 1 (NCEH1) interaction partners

  1. Psoriasis inflammation induced microRNA targets NCEH1 in underlying subcutaneous adipose tissue.

  2. Pioglitazone increases ABCA1 (显示 ABCA1 抗体) expression in an LXR (显示 NR1H3 抗体)-dependent manner and NCEH1 expression in an LXRalpha (显示 NR1H3 抗体)-independent manner.

  3. Inhibition of AADACL1 activity with a variety of agents blocked platelet aggregation in response to multiple agonists; blocked activation of the small GTPase (显示 RACGAP1 抗体) RAP1 (显示 RABGEF1 抗体) and protein kinase C (PKC (显示 PKC 抗体)).

  4. NCEH1 is expressed in human atheromatous lesions, where it plays a critical role in the hydrolysis of cholesterol ester in human macrophage foam cells, thereby contributing to the initial part of reverse cholesterol transport in human atherosclerosis.

  5. Ritonavir (at 100 mg once daily and 100 mg twice daily significantly down-regulated neutral cholesterol ester hydrolase 1 in 20 healthy individuals.

  6. NCEH is responsible for a major part of nCEH activity in macrophages and may be a potential therapeutic target for the prevention of atherosclerosis.

Mouse (Murine) Neutral Cholesterol Ester Hydrolase 1 (NCEH1) interaction partners

  1. These results suggest that Nceh1 plays a dominant role over Lipe (显示 LIPE 抗体) in the hydrolysis of CE and subsequent cholesterol efflux in MPMs

  2. reducing the cholesteryl ester content of foam cells, Nceh1 may protect against the pro-apoptotic effect of oxysterols and modulate the development of atherosclerosis.

  3. Gender difference of atherogenesis is partly accounted for activation of neutral cholesterol ester hydrolase (显示 LIPA 抗体) through estrogen-dependent translocation of A-kinase type II in macrophages.

  4. Nceh1 is involved in the adrenal cholesterol metabolism, and the cholesterol ester hydrolytic activity in adrenal glands is associated with the organ enlargement.

  5. NCEH is targeted to the ER of macrophages, where it hydrolyzes CE to deliver cholesterol for efflux out of the cells.

  6. NCEH is responsible for a major part of nCEH activity in macrophages and may be a potential therapeutic target for the prevention of atherosclerosis.

  7. Genetic ablation of Nceh1 promotes foam cell formation and the development of atherosclerosis in mice.

NCEH1 抗原简介

蛋白简介

Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (By similarity).

Gene names and symbols associated with NCEH1

  • neutral cholesterol ester hydrolase 1 (NCEH1) 抗体
  • neutral cholesterol ester hydrolase 1 (nceh1) 抗体
  • neutral cholesterol ester hydrolase 1 (Nceh1) 抗体
  • Aadacl1 抗体
  • B230106I24Rik 抗体
  • CPO-BP 抗体
  • MGC79479 抗体
  • Nceh 抗体
  • RGD1311104 抗体

Protein level used designations for NCEH1

arylacetamide deacetylase-like 1 , NCEH , neutral cholesterol ester hydrolase 1 , chlorpyrifos oxon-binding protein

GENE ID SPECIES
429158 Gallus gallus
470998 Pan troglodytes
694200 Macaca mulatta
100064432 Equus caballus
100172976 Pongo abelii
493371 Xenopus (Silurana) tropicalis
100010391 Monodelphis domestica
100101305 Xenopus laevis
100395412 Callithrix jacchus
100580453 Nomascus leucogenys
57552 Homo sapiens
488171 Canis lupus familiaris
320024 Mus musculus
294930 Rattus norvegicus
534212 Bos taurus
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