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NTS encodes a common precursor for two peptides, neuromedin N and neurotensin. 再加上，我们可以发Neurotensin 试剂盒 (52) 和 Neurotensin 蛋白 (17)和数多这个蛋白质的别的产品。
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Cat (Feline) Polyclonal Neurotensin Primary Antibody for IEM, ICC - ABIN617885
Woulfe, Beaudet: Neurotensin terminals form synapses primarily with neurons lacking detectable tyrosine hydroxylase immunoreactivity in the rat substantia nigra and ventral tegmental area. in The Journal of comparative neurology 1992
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Amphibian Polyclonal Neurotensin Primary Antibody for IHC (fro), IHC (p) - ABIN113508
Larsson, Alumets, Hakanson, Simonsson, Sundler: Carcinoid granule extract contains antigenic determinants common to peptide hormone-producing cells and endocrine tumours. in Virchows Archiv. A, Pathological anatomy and histopathology 1990
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Human Polyclonal Neurotensin Primary Antibody for IF (p), IHC (p) - ABIN719126
Sakumoto, Hayashi, Saito, Kanahara, Kizaki, Iga: Comparison of the global gene expression profiles in the bovine endometrium between summer and autumn. in The Journal of reproduction and development 2015
Higher concentrations of proneurotensin are associated with a greater risk of incident cardiovascular events in the community. This association did not vary according to sex, baseline low-density lipoprotein, or sortilin (显示 SORT1 抗体) receptor 1 genotype.
sortilin (显示 SORT1 抗体) is a PIP3 binding protein with binding likely to occur at the C-terminal neurotensin binding site, and is a competitor of neurotensin
pretreatment of gastric cancer cells with NTR1 (显示 TFIP11 抗体) inhibitor SR48692 was shown to significantly inhibit the NT-mediated MMP-9 (显示 MMP9 抗体) activity, cell invasion, and migration
NTS/IL-8 (显示 IL8 抗体)/CXCR1 (显示 CXCR1 抗体)/STAT3 (显示 STAT3 抗体) signaling is crucial for the maintenance of stem-like traits in glioblastoma stem cells .
NTS/NTSR1 (显示 NTSR1 抗体) complex enhances breast tumor aggressiveness via EGFR (显示 EGFR 抗体)/HER2 (显示 ERBB2 抗体)/HER3 (显示 ERBB3 抗体) pathway.
Neurotensin and its receptor NTSR1 (显示 NTSR1 抗体) causes EGFR (显示 EGFR 抗体), HER2 (显示 ERBB2 抗体) and HER3 (显示 ERBB3 抗体) over-expression and their autocrine/paracrine activation in lung adenocarcinomas, confirming responsiveness to erlotinib.
indicate that neurotensin is a direct target of the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) pathway and may be a mediator for neuroendocrine tumor cell growth
The antimicrobial peptide (显示 cAMP 抗体) neurotensin has activity against invasive microbes.
Results show that both the neurotensin (NT) and the neurotensin 1 receptor hNTS1(321-344)fragment present a 3D structure in complex.
Neurotensin-mediated calcium signaling appears more sensitive to differentiation than ATP-mediated Ca(2 (显示 CA2 抗体)+) signaling
The pigmented cells of the ocular ciliary epithelium release neurotensin (NT) in response to inducing agents, whereas the nonpigmented cells exhibit a significantly reduced NT secretion in response to inducers, leading to accumulation of the peptide.
Data (including data from studies in transgenic mice) suggest Nts, glucagon-like peptide I (显示 GCG 抗体), and peptide YY are closely co-expressed/co-secreted within enteroendocrine cells in ileum mucosa; however, Nts is stored in distinct/separate secretory granules.
The roles of neurotensin and its receptor NTR-1 on sperm capacitation and acrosome reaction in mice are reported.
These observations suggest the importance of neurotensin in maintaining activity of orexin (显示 OX 抗体) neurons.
a lineage of mature enteroendocrine cells have the ability to coexpress members of a group of functionally related peptides: CCK (显示 CCK 抗体), secretin (显示 SECR 抗体), GIP (显示 GIP 抗体), GLP-1 (显示 GCG 抗体), PYY, and neurotensin
Neurotensin knock-out mice do not differ from their wild-type or heterozygous littermates in either baseline or acute cocaine-stimulated locomotor activity.
Neurotensin increases EGF (显示 EGF 抗体) expression in skin dendritic cells.
NT acutely regulates D2 autoreceptor function and DA neuron excitability through PKC (显示 PKC 抗体)-mediated phosphorylation of the D2R (显示 DRD2 抗体), leading to heterologous receptor desensitization.
although neurotensin neurons in the anteroventral periventricular nucleus are targets for regulation by E(2), neurotensin does not appear to play a direct role in generating the GnRH/LH surge in the mouse
neurotensin has a role in chronic mitogen-activated protein kinase (显示 MAPK1 抗体) activation and cancer progression
NT and NTR1 are part of network activated after mucosal injuries, and NT stimulates epithelial restitution, at least in part, through a COX-2 (显示 COX2 抗体) dependent pathway.
Human, pig, and frog NT and [Gln(4)]NT and [D-Tyr (显示 TYR 抗体)(11)]NT adsorbed to the silver surface via the tyrosine ring, the oxygen atom of the deprotonated phenol group of Tyr (显示 TYR 抗体)(11), and the -CH(2 (显示 Acyp1 抗体))- unit(s), most probably of Tyr (显示 TYR 抗体)(11), Arg(9), and/or Leu(13 (显示 IFITM1 抗体)).
This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.
, neurotensin/neuromedin N
, neuromedin N